AC T08705
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ID T08705
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DT 16.03.2006 (created); sou.
DT 10.06.2016 (updated); smt.
CO Copyright (C), QIAGEN.
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FA Egr-4
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SY AT133; early growth response protein 4; EGR4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004598 EGR4; HGNC: EGR4.
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CL C0001; CH.
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SZ 486 AA; 50.9 kDa (cDNA) (calc.).
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SQ MLHLSEFSEPDALLVKSTEGCCAEPSAELPRLPARDAPAATGYPGAGDFLSWALNSCGAS
SQ GDLADSCFLEGPAPTPPPGLSYSGSFFIQAVPEHPHDPEALFNLMSGVLGLAPFPGPEAA
SQ ASRSPLDAPFPAGSDALLPGPPDLYSPDLGAAPFPEAFWEASPCAGAPSQCLYEPQLSPP
SQ DVKPGLRRPPASPALDAVSAFKGPYAPWELLSVGAPGNCGSQGDYQAAPEARFPVIGTKI
SQ EDLLSISCPAELPAVPANRLYPSGAYDAFPLAPGDLGEGAEGLPGLLTPPSGEGGSSGDG
SQ GEFLASTQPQLSPLGLRSAAAADFPKPLVADIPGSSGVAAPPVPPPPPTPFPQAKARRKG
SQ RRGGKCSTRCFCPRPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFS
SQ RSDHLTSHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLG
SQ LSFASL
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SC translated from EMBL #X60104
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FT 380 404 
PF00096; zf-C2H2.
FT 380 404 
SM00355; c2h2final6.
FT 380 409 
PS50157; ZINC_FINGER_C2H2_2.
FT 410 432 
PF00096; zf-C2H2.
FT 410 432 
SM00355; c2h2final6.
FT 410 437 
PS50157; ZINC_FINGER_C2H2_2.
FT 438 460 
PF00096; zf-C2H2.
FT 438 460 
SM00355; c2h2final6.
FT 438 465 
PS50157; ZINC_FINGER_C2H2_2.
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IN T00593 NF-kappaB1-p50; human, Homo sapiens.
IN T10399 NF-kappaB1-p50; Mammalia.
IN T11025 NFATc1; Mammalia.
IN T11024 NFATc2; Mammalia.
IN T00594 RelA-p65-isoform1; human, Homo sapiens.
IN T14321 RelA-p65; Mammalia.
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MX M08878 V$EGR_Q3.
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BS R65031.
BS R65032.
BS R13412.
BS R65019.
BS R65026.
BS R65028.
BS R65023.
BS R65024.
BS R65030.
BS R14632.
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DR TRANSPATH: MO000079294.
DR TRANSCOMPEL: C00647.
DR TRANSCOMPEL: C00648.
DR EMBL: X60104;
DR EMBL: X69438;
DR UniProtKB: Q05215;
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RN [1]; RE0030092.
RX PUBMED: 12560487.
RA Decker E. L., Nehmann N., Kampen E., Eibel H., Zipfel P. F., Skerka C.
RT Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
RL Nucleic Acids Res. 31:911-21 (2003).
RN [2]; RE0047425.
RX PUBMED: 16014385.
RA Wieland G. D., Nehmann N., Muller D., Eibel H., Siebenlist U., Suhnel J., Zipfel P. F., Skerka C.
RT Early growth response proteins EGR-4 and EGR-3 interact with immune inflammatory mediators NF-kappaB p50 and p65.
RL J. Cell Sci. 118:3203-3212 (2005).
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