TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T11024 XX ID T11024 XX DT 10.03.2005 (created); nvo. DT 15.01.2016 (updated); mkl. CO Copyright (C), QIAGEN. XX FA NFATc2 XX SY NF-AT1; NFATC2; Nuclear Factor of Activated T-cells p. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10346 c-Fos; Mammalia. IN T09446 c-Jun; Mammalia. IN T11261 c-Rel; Mammalia. IN T00241 Egr-1; human, Homo sapiens. IN T09462 Egr-1; human, Homo sapiens. IN T05190 Egr-4; human, Homo sapiens. IN T08705 Egr-4; human, Homo sapiens. IN T10659 Elf-1; Mammalia. IN T30868 IRF-4; Mammalia. IN T11025 NFATc1; Mammalia. IN T23091 p300; Mammalia. IN T08326 Sp1; Mammalia. XX MX M03555 V$NFAT1_Q4. MX M07365 V$NFAT1_Q5. MX M01281 V$NFAT1_Q6. MX M07608 V$NFAT_Q3. MX M00935 V$NFAT_Q4_01. MX M00302 V$NFAT_Q6. XX BS R41541. BS R41543. BS R41545. BS R69777. BS R05071. BS R08170. BS R39585. BS R08188. BS R14422. BS R21079. BS R21082. BS R30080. BS R24087. BS R65783. BS R65786. BS R65787. BS R05081. BS R38404. BS R38405. BS R38406. BS R68499. XX DR TRANSPATH: MO000047016. DR TRANSCOMPEL: C00159. DR TRANSCOMPEL: C00160. DR TRANSCOMPEL: C00163. DR TRANSCOMPEL: C00520. XX RN [1]; RE0016682. RX PUBMED: 9094628. RA Bassuk A. G., Anandappa R. T., Leiden J. M. RT Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells. RL J. Virol. 71:3563-3573 (1997). RN [2]; RE0022702. RX PUBMED: 12021260. RA San-Antonio B., Iniguez M. A., Fresno M. RT Protein kinase Czeta phosphorylates nuclear factor of activated T cells and regulates its transactivating activity. RL J. Biol. Chem. 277:27073-27080 (2002). RN [3]; RE0024034. RX PUBMED: 11313476. RA Kim L. J., Seto A. G., Nguyen T. N., Goodrich J. A. RT Human Taf(II)130 is a coactivator for NFATp. RL Mol. Cell. Biol. 21:3503-3513 (2001). RN [4]; RE0029434. RX PUBMED: 11956291. RA Rengarajan J., Mowen K. A., McBride K. D., Smith E. D., Singh H., Glimcher L. H. RT Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression. RL J. Exp. Med. 195:1003-12 (2002). RN [5]; RE0029679. RX PUBMED: 12195013. RA Diehn M., Alizadeh A. A., Rando O. J., Liu C. L., Stankunas K., Botstein D., Crabtree G. R., Brown P. O. RT Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. RL Proc. Natl. Acad. Sci. USA 99:11796-801 (2002). RN [6]; RE0030092. RX PUBMED: 12560487. RA Decker E. L., Nehmann N., Kampen E., Eibel H., Zipfel P. F., Skerka C. RT Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. RL Nucleic Acids Res. 31:911-21 (2003). RN [7]; RE0032250. RX PUBMED: 11493684. RA Santini M. P., Talora C., Seki T., Bolgan L., Dotto G. P. RT Cross talk among calcineurin, Sp1/Sp3, and NFAT in control of p21(WAF1/CIP1) expression in keratinocyte differentiation. RL Proc. Natl. Acad. Sci. USA 98:9575-80 (2001). RN [8]; RE0033399. RX PUBMED: 15314684. RA Ikeda F., Nishimura R., Matsubara T., Tanaka S., Inoue J., Reddy S. V., Hata K., Yamashita K., Hiraga T., Watanabe T., Kukita T., Yoshioka K., Rao A., Yoneda T. RT Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. RL J. Clin. Invest. 114:475-84 (2004). RN [9]; RE0033797. RX PUBMED: 15121840. RA Okamura H., Garcia-Rodriguez C., Martinson H., Qin J., Virshup D. M., Rao A. RT A conserved docking motif for CK1 binding controls the nuclear localization of NFAT1. RL Mol. Cell. Biol. 24:4184-95 (2004). RN [10]; RE0040292. RX PUBMED: 10788511. RA Gomez del Arco P., Martinez-Martinez S., Maldonado J. L., Ortega-Perez I., Redondo J. M. RT A role for the p38 MAP kinase pathway in the nuclear shuttling of NFATp RL J. Biol. Chem. 275:13872-8 (2000). RN [11]; RE0043112. RX PUBMED: 7650486. RA Aramburu J., Azzoni L., Rao A., Perussia B. RT Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding RL J. Exp. Med. 182:801-10 (1995). RN [12]; RE0043264. RX PUBMED: 12093869. RA Diehl S., Chow C. W., Weiss L., Palmetshofer A., Twardzik T., Rounds L., Serfling E., Davis R. J., Anguita J., Rincon M. RT Induction of NFATc2 expression by interleukin 6 promotes T helper type 2 differentiation RL J. Exp. Med. 196:39-49 (2002). RN [13]; RE0043457. RX PUBMED: 15031636. RA Kadereit S., Junge G. R., Kleen T., Kozik M. M., Kaminski B. A., Daum-Woods K., Fu P., Tary-Lehmann M., Laughlin M. J. RT Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression RL J. Clin. Immunol. 23:485-97 (2003). RN [14]; RE0047284. RX PUBMED: 12226086. RA van Rooij E., Doevendans P. A., de Theije C. C., Babiker F. A., Molkentin J. D., De Windt L. J. RT Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy RL J. Biol. Chem. 277:48617-26 (2002). RN [15]; RE0071979. RX PUBMED: 17398070. RA Gomez-Casero E., San-Antonio B., Iniguez M. A., Fresno M. RT Cot/Tpl2 and PKCzeta cooperate in the regulation of the transcriptional activity of NFATc2 through the phosphorylation of its amino-terminal domain. RL Cell. Signal. 19:1652-1661 (2007). XX //