TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T09447 XX ID T09447 XX DT 10.03.2005 (created); nvo. DT 23.05.2014 (updated); vad. CO Copyright (C), QIAGEN. XX FA JunD XX SY AP-1; jun D proto-oncogene; TRANSCRIPTION FACTOR JUN-D. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T16043 BCL-6; Mammalia. IN T04074 brca1; human, Homo sapiens. IN T15204 brca1; Mammalia. IN T10346 c-Fos; Mammalia. IN T09446 c-Jun; Mammalia. IN T23077 CHOP-10; Mammalia. IN T00261 ER-alpha; human, Homo sapiens. IN T30386 Fra-1; Mammalia. IN T30385 Fra-2; Mammalia. IN T09354 Hex; mouse, Mus musculus. IN T14353 HOXC-8; mouse, Mus musculus. IN T06578 jdp2; rat, Rattus norvegicus. IN T10510 JunB; Mammalia. IN T11025 NFATc1; Mammalia. IN T13730 Nrf2; Mammalia. IN T09963 PPARgamma; Mammalia. IN T10783 Smad1; Mammalia. IN T09538 Smad3; Mammalia. IN T13998 Smad4; Mammalia. IN T14175 TBP; Mammalia. XX MX M00517 V$AP1_01. MX M00924 V$AP1_Q2_01. MX M00926 V$AP1_Q4_01. MX M00925 V$AP1_Q6_01. MX M03552 V$JUND_Q6. XX BS R61970. BS R24701. BS R19598. BS R72456. XX DR TRANSPATH: MO000047201. DR TRANSCOMPEL: C00195. DR TRANSCOMPEL: C00629. XX RN [1]; RE0011961. RX PUBMED: 7759510. RA Welter J. F., Crish J. F., Agarwal C., Eckert R. L. RT Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity RL J. Biol. Chem. 270:12614-12622 (1995). RN [2]; RE0025071. RX PUBMED: 10657527. RA Yukimasa N., Isobe K., Nagai H., Takuwa Y., Nakai T. RT Successive occupancy by immediate early transcriptional factors of the tyrosine hydroxylase gene TRE and CRE sites in PACAP-stimulated PC12 pheochromocytoma cells. RL Neuropeptides 33:475-482 (1999). RN [3]; RE0026769. RX PUBMED: 10934195. RA Sharma S. C., Richards J. S. RT Regulation of AP1 (Jun/Fos) factor expression and activation in ovarian granulosa cells. Relation of JunD and Fra2 to terminal differentiation. RL J. Biol. Chem. 275:33718-28 (2000). RN [4]; RE0027756. RX PUBMED: 10559251. RA Wild A. C., Moinova H. R., Mulcahy R. T. RT Regulation of gamma-glutamylcysteine synthetase subunit gene expression by the transcription factor Nrf2. RL J. Biol. Chem. 274:33627-36 (1999). RN [5]; RE0029294. RX PUBMED: 11698415. RA Balasubramanian S., Efimova T., Eckert R. L. RT Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes. RL J. Biol. Chem. 277:1828-36 (2002). RN [6]; RE0031549. RX PUBMED: 11477071. RA Teyssier C., Belguise K., Galtier F., Chalbos D. RT Characterization of the physical interaction between estrogen receptor alpha and JUN proteins. RL J. Biol. Chem. 276:36361-9 (2001). RN [7]; RE0031869. RX PUBMED: 15051730. RA Bertrand-Philippe M., Ruddell R. G., Arthur M. J., Thomas J., Mungalsingh N., Mann D. A. RT Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2. RL J. Biol. Chem. 279:24530-9 (2004). RN [8]; RE0032053. RX PUBMED: 10749670. RA Olsen J., Lefebvre O., Fritsch C., Troelsen J. T., Orian-Rousseau V., Kedinger M., Simon-Assmann P. RT Involvement of activator protein 1 complexes in the epithelium-specific activation of the laminin gamma2-chain gene promoter by hepatocyte growth factor (scatter factor). RL Biochem. J. 347:407-17 (2000). RN [9]; RE0032082. RX PUBMED: 11841562. RA Jha N., Kumar M. J., Boonplueang R., Andersen J. K. RT Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease? RL J. Neurochem 80:555-61 (2002). RN [10]; RE0038287. RX PUBMED: 9651314. RA Virolle T., Monthouel M. N., Djabari Z., Ortonne J. P., Meneguzzi G., Aberdam D. RT Three activator protein-1-binding sites bound by the Fra-2.JunD complex cooperate for the regulation of murine laminin alpha3A (lama3A) promoter activity by transforming growth factor-beta RL J. Biol. Chem. 273:17318-25 (1998). RN [11]; RE0038477. RX PUBMED: 11057875. RA Ishii H., Takada K., Higuchi T., Sugiyama J. RT Verotoxin-1 induces tissue factor expression in human umbilical vein endothelial cells through activation of NF-kappaB/Rel and AP-1 RL Thromb. Haemost. 84:712-21 (2000). RN [12]; RE0039865. RX PUBMED: 12021209. RA Sayo Y., Murao K., Imachi H., Cao W. M., Sato M., Dobashi H., Wong N. C., Ishida T. RT The multiple endocrine neoplasia type 1 gene product, menin, inhibits insulin production in rat insulinoma cells RL Endocrinology 143:2437-40 (2002). RN [13]; RE0039867. RX PUBMED: 14767471. RA Shen Q., Singh P. RT Identification of a novel SP3 binding site in the promoter of human IGFBP4 gene: role of SP3 and AP-1 in regulating promoter activity in CaCo2 cells RL Oncogene 23:2454-64 (2004). RN [14]; RE0039869. RX PUBMED: 12177049. RA Kannan-Thulasiraman P., Shapiro D. J. RT Modulators of inflammation use nuclear factor-kappa B and activator protein-1 sites to induce the caspase-1 and granzyme B inhibitor, proteinase inhibitor 9 RL J. Biol. Chem. 277:41230-9 (2002). RN [15]; RE0039871. RX PUBMED: 11689285. RA Hayes J. D., McMahon M. RT Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention RL Cancer Lett. 174:103-13 (2001). RN [16]; RE0039877. RX PUBMED: 9651321. RA Takahashi H., Asano K., Kinouchi M., Ishida-Yamamoto A., Wuepper K. D., Iizuka H. RT Structure and transcriptional regulation of the human cystatin A gene. The 12-O-tetradecanoylphorbol-13-acetate (TPA) responsive element-2 site (-272 to -278) on cystatin A gene is critical for TPA-dependent regulation RL J. Biol. Chem. 273:17375-80 (1998). RN [17]; RE0039879. RX PUBMED: 11382925. RA David J. P., Rincon M., Neff L., Horne W. C., Baron R. RT Carbonic anhydrase II is an AP-1 target gene in osteoclasts RL J. Cell. Physiol. 188:89-97 (2001). RN [18]; RE0039880. RX PUBMED: 12622720. RA Wu L., Tanimoto A., Murata Y., Sasaguri T., Fan J., Sasaguri Y., Watanabe T. RT Matrix metalloproteinase-12 gene expression in human vascular smooth muscle cells RL Genes Cells 8:225-34 (2003). RN [19]; RE0041027. RX PUBMED: 8750873. RA Pennypacker K. R., Lennard D. E., Hudson P. M., Hong J. S., McMillian M. K. RT Basal expression of 35 kDa fos-related antigen in olfactory bulb RL Mol. Brain Res. 34:161-5 (1995). RN [20]; RE0042992. RX PUBMED: 12445671. RA Poisson A., Zablewska B., Gaudray P. RT Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1 RL Cancer Lett. 189:1-10 (2003). RN [21]; RE0043685. RX PUBMED: 12054733. RA Gunthert A. R., Grundker C., Hollmann K., Emons G. RT Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells RL Biochem. Biophys. Res. Commun. 294:11-5 (2002). RN [22]; RE0043687. RX PUBMED: 14702344. RA Hazra S., Xiong S., Wang J., Rippe R. A., Krishna V., Chatterjee K., Tsukamoto H. RT Peroxisome proliferator-activated receptor gamma induces a phenotypic switch from activated to quiescent hepatic stellate cells RL J. Biol. Chem. 279:11392-401 (2004). RN [23]; RE0043769. RX PUBMED: 8114760. RA Kimura E., Sonobe M. H., Armelin M. C., Armelin H. A. RT Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives RL Mol. Endocrinol. 7:1463-71 (1993). RN [24]; RE0045718. RX PUBMED: 10974538. RA Jessen B. A., Qin Q., Rice R. H. RT Functional AP1 and CRE response elements in the human keratinocyte transglutaminase promoter mediating Whn suppression RL Gene 254:77-85 (2000). RN [25]; RE0047040. RX PUBMED: 15087382. RA Brellier F., Marionnet C., Chevallier-Lagente O., Toftgard R., Mauviel A., Sarasin A., Magnaldo T. RT Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process RL Cancer Res. 64:2699-704 (2004). RN [26]; RE0047533. RX PUBMED: 10523647. RA Ubeda M., Vallejo M., Habener J. F. RT CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins. RL Mol. Cell. Biol. 19:7589-7599 (1999). RN [27]; RE0048037. RX PUBMED: 12080089. RA Hu Y. F., Li R. RT JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction. RL Genes Dev. 16:1509-1517 (2002). RN [28]; RE0048088. RX PUBMED: 8945519. RA Kallunki T., Deng T., Hibi M., Karin M. RT c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. RL Cell 87:929-939 (1996). RN [29]; RE0052694. RX PUBMED: 11551904. RA Schaefer L. K., Wang S., Schaefer T. S. RT Functional interaction of Jun and homeodomain proteins. RL J. Biol. Chem. 276:43074-43082 (2001). RN [30]; RE0070404. RX PUBMED: 20516211. RA Da Costa C. R., Villadiego J., Sancho R., Fontana X., Packham G., Nateri A. S., Behrens A. RT Bag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis. RL Mol. Cell. Biol. 30:3842-3852 (2010). XX //