AC T14315
XX
ID T14315
XX
DT 10.03.2005 (created); nvo.
DT 16.06.2016 (updated); mom.
CO Copyright (C), QIAGEN.
XX
FA AML1
XX
SY Acute Myeloid Leukemia 1.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T15601 AR; Mammalia.
IN T10346 c-Fos; Mammalia.
IN T08664 C/EBPalpha; Mammalia.
IN T00305 GATA-1; mouse, Mus musculus.
IN T10217 GATA-1; Mammalia.
IN T06585 gfi1b; mouse, Mus musculus.
IN T11323 Myef2; mouse, Mus musculus.
IN T01427 p300; human, Homo sapiens.
IN T21984 p300; human, Homo sapiens.
IN T10303 Pax-5; Mammalia.
IN T01064 PEBP2beta; mouse, Mus musculus.
IN T23072 PEBP2beta; Mammalia.
IN T16151 Tal-1; mouse, Mus musculus.
IN T08482 VDR-isoform1; human, Homo sapiens.
IN T22878 YAP-isoform3; human, Homo sapiens.
XX
MX M00271 V$AML1_01.
MX M01658 V$AML1_Q4.
MX M07242 V$AML1_Q4_01.
MX M08865 V$AML1_Q4_02.
MX M02084 V$AML1_Q5.
MX M00751 V$AML1_Q6.
MX M08866 V$AML_Q4.
MX M00769 V$AML_Q6.
MX M00984 V$PEBP_Q6.
XX
BS R23967.
BS R35403.
BS R23963.
BS R23964.
BS R41295.
BS R37986.
BS R37987.
BS R37988.
BS R31620.
BS R71799.
BS R41297.
BS R42042.
BS R64807.
BS R63243.
BS R63245.
BS R63246.
BS R37602.
BS R37603.
BS R37604.
BS R37991.
BS R37992.
BS R37606.
BS R37608.
BS R73872.
BS R19732.
BS R63247.
BS R63248.
BS R63249.
XX
DR TRANSPATH: MO000047768.
DR TRANSCOMPEL: C00020.
XX
RN [1]; RE0006054.
RX PUBMED: 9106660.
RA Mayall T. P., Sheridan P. L., Montminy M. R., Jones K. A.
RT Distinct roles for P-CREB and LEF-1 in TCRalpha enhancer assembly and activation on chromatin templates in vitro
RL Genes Dev. 11:887-899 (1997).
RN [2]; RE0013411.
RX PUBMED: 9751710.
RA Levanon D., Goldstein R. E., Bernstein Y., Tang H., Goldenberg D., Stifani S., Paroush Z., Groner Y.
RT Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors
RL Proc. Natl. Acad. Sci. USA 95:11590-11595 (1998).
RN [3]; RE0016671.
RX PUBMED: 9632776.
RA Petrovick M. S., Hiebert S. W., Friedman A. D., Hetherington C. J., Tenen D. G., Zhang D.-E.
RT Multiple functional domains of AML1: PU.1 and C/EBPalpha synergize with different regions of AML1.
RL Mol. Cell. Biol. 18:3915-3925 (1998).
RN [4]; RE0023220.
RX PUBMED: 11274169.
RA Hess J., Porte D., Munz C., Angel P.
RT AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite element.
RL J. Biol. Chem. 276:20029-20038 (2001).
RN [5]; RE0030245.
RX PUBMED: 12576332.
RA Elagib K. E., Racke F. K., Mogass M., Khetawat R., Delehanty L. L., Goldfarb A. N.
RT RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation.
RL Blood 101:4333-41 (2003).
RN [6]; RE0031869.
RX PUBMED: 15051730.
RA Bertrand-Philippe M., Ruddell R. G., Arthur M. J., Thomas J., Mungalsingh N., Mann D. A.
RT Regulation of tissue inhibitor of metalloproteinase 1 gene transcription by RUNX1 and RUNX2.
RL J. Biol. Chem. 279:24530-9 (2004).
RN [7]; RE0034431.
RX PUBMED: 12771199.
RA Bristow C. A., Shore P.
RT Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ.
RL Nucleic Acids Res. 31:2735-44 (2003).
RN [8]; RE0035828.
RX PUBMED: 10521447.
RA Ning Y. M., Robins D. M.
RT AML3/CBFalpha1 is required for androgen-specific activation of the enhancer of the mouse sex-limited protein (Slp) gene.
RL J. Biol. Chem. 274:30624-30630 (1999).
RN [9]; RE0036612.
RX PUBMED: 14617032.
RA Nielsen C., Hansen D., Husby S., Jacobsen B. B., Lillevang S. T.
RT Association of a putative regulatory polymorphism in the PD-1 gene with susceptibility to type 1 diabetes
RL Tissue Antigens 62:492-7 (2003).
RN [10]; RE0038828.
RX PUBMED: 14623259.
RA Lennartsson A., Pieters K., Ullmark T., Vidovic K., Gullberg U.
RT AML-1, PU.1, and Sp3 regulate expression of human bactericidal/permeability-increasing protein
RL Biochem. Biophys. Res. Commun. 311:853-63 (2003).
RN [11]; RE0039427.
RX PUBMED: 9606182.
RA Kitabayashi I., Yokoyama A., Shimizu K., Ohki M.
RT Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation
RL EMBO J. 17:2994-3004 (1998).
RN [12]; RE0039432.
RX PUBMED: 12172539.
RA Lukasik S. M., Zhang L., Corpora T., Tomanicek S., Li Y., Kundu M., Hartman K., Liu P. P., Laue T. M., Biltonen R. L., Speck N. A., Bushweller J. H.
RT Altered affinity of CBF beta-SMMHC for Runx1 explains its role in leukemogenesis
RL Nat. Struct. Biol. 9:674-9 (2002).
RN [13]; RE0039433.
RX PUBMED: 11742995.
RA Kitabayashi I., Aikawa Y., Nguyen L. A., Yokoyama A., Ohki M.
RT Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein
RL EMBO J. 20:7184-96 (2001).
RN [14]; RE0039456.
RX PUBMED: 12917624.
RA Chakraborty S., Sinha K. K., Senyuk V., Nucifora G.
RT SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo
RL Oncogene 22:5229-37 (2003).
RN [15]; RE0039457.
RX PUBMED: 14608356.
RA Tokuhiro S., Yamada R., Chang X., Suzuki A., Kochi Y., Sawada T., Suzuki M., Nagasaki M., Ohtsuki M., Ono M., Furukawa H., Nagashima M., Yoshino S., Mabuchi A., Sekine A., Saito S., Takahashi A., Tsunoda T., Nakamura Y., Yamamoto K.
RT An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
RL Nat. Genet. 35:341-8 (2003).
RN [16]; RE0039460.
RX PUBMED: 10617663.
RA Lutterbach B., Westendorf J. J., Linggi B., Isaac S., Seto E., Hiebert S. W.
RT A mechanism of repression by acute myeloid leukemia-1, the target of multiple chromosomal translocations in acute leukemia
RL J. Biol. Chem. 275:651-6 (2000).
RN [17]; RE0042557.
RX PUBMED: 15138260.
RA Jin Y. H., Jeon E. J., Li Q. L., Lee Y. H., Choi J. K., Kim W. J., Lee K. Y., Bae S. C.
RT Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation
RL J. Biol. Chem. 279:29409-17 (2004).
RN [18]; RE0044364.
RX PUBMED: 12933821.
RA Rehli M., Niller H. H., Ammon C., Langmann S., Schwarzfischer L., Andreesen R., Krause S. W.
RT Transcriptional regulation of CHI3L1, a marker gene for late stages of macrophage differentiation
RL J. Biol. Chem. 278:44058-67 (2003).
RN [19]; RE0047451.
RX PUBMED: 12460926.
RA Puccetti E., Obradovic D., Beissert T., Bianchini A., Washburn B., Chiaradonna F., Boehrer S., Hoelzer D., Ottmann O. G., Pelicci P. G., Nervi C., Ruthardt M.
RT AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.
RL Cancer Res. 62:7050-7058 (2002).
XX
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