TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10217 XX ID T10217 XX DT 10.03.2005 (created); nvo. DT 11.12.2014 (updated); asv. CO Copyright (C), QIAGEN. XX FA GATA-1 XX SY EF1 (chick); EFgammaa; Eryf1 (chick); GATA-1; GF-1; NF-E1. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T14315 AML1; Mammalia. IN T17679 c-Myb; Mammalia. IN T09410 C/EBPbeta; Mammalia. IN T10891 C/EBPepsilon; Mammalia. IN T02252 CLIM2; mouse, Mus musculus. IN T10058 Fli-1; mouse, Mus musculus. IN T02334 FOG; mouse, Mus musculus. IN T14726 FOG; mouse, Mus musculus. IN T06585 gfi1b; mouse, Mus musculus. IN T10446 GR; Mammalia. IN T23418 HDAC1; mouse, Mus musculus. IN T13841 HES-1; Mammalia. IN T00479 Ikaros; mouse, Mus musculus. IN T17042 MBD2; mouse, Mus musculus. IN T05115 MTA1L1; human, Homo sapiens. IN T09976 PU.1; human, Homo sapiens. IN T10037 PU.1; Mammalia. IN T14264 RBTN2; Mammalia. IN T10783 Smad1; Mammalia. IN T08326 Sp1; Mammalia. IN T01574 STAT3; mouse, Mus musculus. IN T14458 STAT3; Mammalia. IN T16151 Tal-1; mouse, Mus musculus. IN T27798 Tal-1; Mammalia. XX MX M00075 V$GATA1_01. MX M00126 V$GATA1_02. MX M00127 V$GATA1_03. MX M00128 V$GATA1_04. MX M00346 V$GATA1_05. MX M00347 V$GATA1_06. MX M02004 V$GATA1_Q6. MX M00203 V$GATA_C. MX M00789 V$GATA_Q6. XX BS R28280. BS R36562. BS R32565. BS R41039. BS R41045. BS R21050. BS R32526. BS R41619. BS R20602. BS R39832. BS R39835. BS R69967. BS R61872. BS R61884. BS R61890. BS R61418. BS R61420. BS R61421. BS R65244. BS R56101. BS R41960. BS R03213. BS R31332. BS R33241. BS R33242. BS R36848. BS R32625. BS R32626. XX DR TRANSPATH: MO000046981. XX RN [1]; RE0000452. RX PUBMED: 2050118. RA Joulin V., Bouries D., Eleouet J.-F., Labastie M.-C., Chretien S., Mattei M.-G., Romeo P.-H. RT A t-cell specific TCR delta DNA binding protein is a member of the human GATA family RL EMBO J. 10:1809-1816 (1991). RN [2]; RE0001005. RX PUBMED: 2050690. RA McDonagh K. T., Lin H. J., Lowrey C. H., Bodine D. M., Nienhuis A. W. RT The upstream region of the human gamma-globin gene promoter RL J. Biol. Chem. 266:11965-11974 (1991). RN [3]; RE0010167. RX PUBMED: 7983009. RA tugores A., Magness S. T., Brenner D. A. RT A single promoter directs both housekeeping and erythroid preferential expression of the human ferrochelatase gene RL J. Biol. Chem. 269:30789-30797 (1994). RN [4]; RE0023129. RX PUBMED: 10644678. RA Aizencang G. I., Bishop D. F., Forrest D., Astrin K. H., Desnick R. J. RT Uroporphyrinogen III synthase. An alternative promoter controls erythroid-specific expression in the murine gene. RL J. Biol. Chem. 275:2295-2304 (2000). RN [5]; RE0023179. RX PUBMED: 12202480. RA Du J., Stankiewicz M. J., Liu Y., Xi Q., Schmitz J. E., Lekstrom-Himes J. A., Ackerman S. J. RT Novel combinatorial interactions of GATA-1, PU.1, and C/EBPepsilon isoforms regulate transcription of the gene encoding eosinophil granule major basic protein. RL J. Biol. Chem. 277:43481-43494 (2002). RN [6]; RE0030245. RX PUBMED: 12576332. RA Elagib K. E., Racke F. K., Mogass M., Khetawat R., Delehanty L. L., Goldfarb A. N. RT RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation. RL Blood 101:4333-41 (2003). RN [7]; RE0031242. RX PUBMED: 11544260. RA Ingley E., Chappell D., Poon S. Y., Sarna M. K., Beaumont J. G., Williams J. H., Stillitano J. P., Tsai S., Leedman P. J., Tilbrook P. A., Klinken S. P. RT Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells. RL J. Biol. Chem. 276:43428-34 (2001). RN [8]; RE0031520. RX PUBMED: 10666199. RA Tanaka H., Matsumura I., Nakajima K., Daino H., Sonoyama J., Yoshida H., Oritani K., Machii T., Yamamoto M., Hirano T., Kanakura Y. RT GATA-1 blocks IL-6-induced macrophage differentiation and apoptosis through the sustained expression of cyclin D1 and bcl-2 in a murine myeloid cell line M1. RL Blood 95:1264-73 (2000). RN [9]; RE0031699. RX PUBMED: 10438731. RA Yamaguchi Y., Nishio H., Kishi K., Ackerman S. J., Suda T. RT C/EBPbeta and GATA-1 synergistically regulate activity of the eosinophil granule major basic protein promoter: implication for C/EBPbeta activity in eosinophil gene expression. RL Blood 94:1429-39 (1999). RN [10]; RE0032945. RX PUBMED: 7649975. RA Nagata Y., Nagahisa H., Aida Y., Okutomi K., Nagasawa T., Todokoro K. RT Thrombopoietin induces megakaryocyte differentiation in hematopoietic progenitor FDC-P2 cells. RL J. Biol. Chem. 270:19673-5 (1995). RN [11]; RE0035546. RX PUBMED: 9859997. RA Boyes J., Byfield P., Nakatani Y., Ogryzko V. RT Regulation of activity of the transcription factor GATA-1 by acetylation. RL Nature 396:594-598 (1998). RN [12]; RE0036313. RX PUBMED: 10037687. RA Gallagher P. G., Sabatino D. E., Romana M., Cline A. P., Garrett L. J., Bodine D. M., Forget B. G. RT A human beta-spectrin gene promoter directs high level expression in erythroid but not muscle or neural cells RL J. Biol. Chem. 274:6062-73 (1999). RN [13]; RE0036544. RX PUBMED: 14749362. RA Lahlil R., Lecuyer E., Herblot S., Hoang T. RT SCL assembles a multifactorial complex that determines glycophorin A expression RL Mol. Cell. Biol. 24:1439-52 (2004). RN [14]; RE0037433. RX PUBMED: 12724402. RA Eisbacher M., Holmes M. L., Newton A., Hogg P. J., Khachigian L. M., Crossley M., Chong B. H. RT Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding RL Mol. Cell. Biol. 23:3427-41 (2003). RN [15]; RE0037434. RX PUBMED: 11418466. RA Freson K., Devriendt K., Matthijs G., Van Hoof A., De Vos R., Thys C., Minner K., Hoylaerts M. F., Vermylen J., Van Geet C. RT Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation RL Blood 98:85-92 (2001). RN [16]; RE0037957. RX PUBMED: 11283251. RA Ranganath S., Murphy K. M. RT Structure and specificity of GATA proteins in Th2 development RL Mol. Cell. Biol. 21:2716-25 (2001). RN [17]; RE0041111. RX PUBMED: 10395650. RA Nishiyama C., Yokota T., Okumura K., Ra C. RT The transcription factors Elf-1 and GATA-1 bind to cell-specific enhancer elements of human high-affinity IgE receptor alpha-chain gene RL J. Immunol. 163:623-30 (1999). RN [18]; RE0042219. RX PUBMED: 10037697. RA Kida M., Souri M., Yamamoto M., Saito H., Ichinose A. RT Transcriptional regulation of cell type-specific expression of the TATA-less A subunit gene for human coagulation factor XIII RL J. Biol. Chem. 274:6138-47 (1999). RN [19]; RE0043062. RX PUBMED: 11322887. RA Cook M., Caswell R. C., Richards R. J., Kay J., Tatnell P. J. RT Regulation of human and mouse procathepsin E gene expression RL Eur. J. Biochem. 268:2658-68 (2001). RN [20]; RE0044020. RX PUBMED: 9651486. RA Masaki S., Kamachi Y., Quinlan R. A., Yonezawa S., Kondoh H. RT Identification and functional analysis of the mouse lens filensin gene promoter RL Gene 214:77-86 (1998). RN [21]; RE0044219. RX PUBMED: 8265595. RA Chiba T., Nagata Y., Kishi A., Sakamaki K., Miyajima A., Yamamoto M., Engel J. D., Todokoro K. RT Induction of erythroid-specific gene expression in lymphoid cells RL Proc. Natl. Acad. Sci. USA 90:11593-7 (1993). RN [22]; RE0044242. RX PUBMED: 10835348. RA Shirihai O. S., Gregory T., Yu C., Orkin S. H., Weiss M. J. RT ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation RL EMBO J. 19:2492-502 (2000). RN [23]; RE0045305. RX PUBMED: 8502237. RA Chang T. J., Scher B. M., Waxman S., Scher W. RT Inhibition of mouse GATA-1 function by the glucocorticoid receptor: possible mechanism of steroid inhibition of erythroleukemia cell differentiation RL Mol. Endocrinol. 7:528-42 (1993). RN [24]; RE0045775. RX PUBMED: 12556498. RA Starck J., Cohet N., Gonnet C., Sarrazin S., Doubeikovskaia Z., Doubeikovski A., Verger A., Duterque-Coquillaud M., Morle F. RT Functional cross-antagonism between transcription factors FLI-1 and EKLF RL Mol. Cell. Biol. 23:1390-402 (2003). RN [25]; RE0046270. RX PUBMED: 14560005. RA Xu Z., Huang S., Chang L. S., Agulnick A. D., Brandt S. J. RT Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation RL Mol. Cell. Biol. 23:7585-99 (2003). RN [26]; RE0046273. RX PUBMED: 12377757. RA Furihata K., Kunicki T. J. RT Characterization of human glycoprotein VI gene 5' regulatory and promoter regions RL Arterioscler. Thromb. Vasc. Biol. 22:1733-9 (2002). RN [27]; RE0046278. RX PUBMED: 12359731. RA Holmes M. L., Bartle N., Eisbacher M., Chong B. H. RT Cloning and analysis of the thrombopoietin-induced megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1 RL J. Biol. Chem. 277:48333-41 (2002). RN [28]; RE0046341. RX PUBMED: 11001896. RA Matsumura I., Kawasaki A., Tanaka H., Sonoyama J., Ezoe S., Minegishi N., Nakajima K., Yamamoto M., Kanakura Y. RT Biologic significance of GATA-1 activities in Ras-mediated megakaryocytic differentiation of hematopoietic cell lines RL Blood 96:2440-50 (2000). RN [29]; RE0047322. RX PUBMED: 15673499. RA Ezoe S., Matsumura I., Gale K., Satoh Y., Ishikawa J., Mizuki M., Takahashi S., Minegishi N., Nakajima K., Yamamoto M., Enver T., Kanakura Y. RT GATA transcription factors inhibit cytokine-dependent growth and survival of a hematopoietic cell line through the inhibition of STAT3 activity. RL J. Biol. Chem. 280:13163-13170 (2005). RN [30]; RE0048127. RX PUBMED: 10411939. RA Zhang P., Behre G., Pan J., Iwama A., Wara-Aswapati N., Radomska H. S., Auron P. E., Tenen D. G., Sun Z. RT Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1. RL Proc. Natl. Acad. Sci. USA 96:8705-8710 (1999). RN [31]; RE0048895. RX PUBMED: 15563463. RA Ishiko E., Matsumura I., Ezoe S., Gale K., Ishiko J., Satoh Y., Tanaka H., Shibayama H., Mizuki M., Era T., Enver T., Kanakura Y. RT Notch signals inhibit the development of erythroid/megakaryocytic cells by suppressing GATA-1 activity through the induction of HES1. RL J. Biol. Chem. 280:4929-4939 (2005). RN [32]; RE0049701. RX PUBMED: 17167422. RA Ribeil J. A., Zermati Y., Vandekerckhove J., Cathelin S., Kersual J., Dussiot M., Coulon S., Moura I. C., Zeuner A., Kirkegaard-Sorensen T., Varet B., Solary E., Garrido C., Hermine O. RT Hsp70 regulates erythropoiesis by preventing caspase-3-mediated cleavage of GATA-1. RL Nature 445:102-105 (2007). RN [33]; RE0054660. RX PUBMED: 15537384. RA Roger T., Miconnet I., Schiesser A. L., Kai H., Miyake K., Calandra T. RT Critical role for Ets, AP-1 and GATA-like transcription factors in regulating mouse Toll-like receptor 4 (Tlr4) gene expression. RL Biochem. J. 387:355-365 (2005). RN [34]; RE0065122. RX PUBMED: 15467009. RA Mura C., Le Gac G., Jacolot S., Ferec C. RT Transcriptional regulation of the human HFE gene indicates high liver expression and erythropoiesis coregulation. RL FASEB J. 18:1922-1924 (2004). RN [35]; RE0070563. RX PUBMED: 21689417. RA Shackleford T. J., Zhang Q., Tian L., Vu T. T., Korapati A. L., Baumgartner A., Le X. F., Liao W. S., Claret F. X. RT Stat3 and CCAAT/enhancer binding protein beta (C/EBP-beta) regulate Jab1/CSN5 expression in mammary carcinoma cells. RL Breast Cancer Res. 13:R65 (2011). XX //