AC T02252
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ID T02252
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DT 29.10.1997 (created); ewi.
DT 20.08.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA CLIM2
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SY carboxy terminal LIM domain protein 2; Ldb1; LIM domain binding protein 1; NLI.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006357 Ldb1.
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HO Chip T04201 (Drosophila).
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SF physical interaction with Lhx9 T04192 [5] [6];
SF physical interaction with Lhx6.1 T04187 T04188 [4];
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FF Expression decreased by DMSO treatment in MEL cells [7];
FF may modulate the regulatory function of LIM-homeo domain transcription factors [4];
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IN T10217 GATA-1; Mammalia.
IN T04187 lhx6.1-isoform1; mouse, Mus musculus.
IN T04188 lhx6.1-isoform2; mouse, Mus musculus.
IN T04192 Lhx9-isoform1; mouse, Mus musculus.
IN T01961 Lim-1; mouse, Mus musculus.
IN T02249 LMO1; human, Homo sapiens.
IN T06090 Lmo4; mouse, Mus musculus.
IN T02250 RBTN2-isoform1; human, Homo sapiens.
IN T02251 RBTN2; mouse, Mus musculus.
IN T16151 Tal-1; mouse, Mus musculus.
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DR TRANSPATH: MO000026259.
DR UniProtKB: P70662;
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RN [1]; RE0006080.
RX PUBMED: 8876198.
RA Jurata L. W., Kenny D. A., Gill G. N.
RT Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development
RL Proc. Natl. Acad. Sci. USA 93:11693-11698 (1996).
RN [2]; RE0006081.
RX PUBMED: 8918878.
RA Agulnick A. D., Taira M., Breen J. J., Tanaka T., Dawid I. B., Westphal H.
RT Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins
RL Nature 384:270-272 (1996).
RN [3]; RE0013512.
RX PUBMED: 9192866.
RA Bach I., Carriere C., Ostendorff H. P., Andersen B., Rosenfeld M. G.
RT A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins.
RL Genes Dev. 11:1370-1380 (1997).
RN [4]; RE0015585.
RX PUBMED: 10393337.
RA Kimura N., Ueno M., Nakashima K., Taga T.
RT A brain region-specific gene product Lhx6.1 interacts with Ldb1 through tandem LIM-domains
RL J. Biochem. 126:180-187 (1999).
RN [5]; RE0015590.
RX PUBMED: 9880598.
RA Retaux S., Rogard M., Bach I., Failli V., Besson M. J.
RT Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain
RL J. Neurosci. 19:783-793 (1999).
RN [6]; RE0015591.
RX PUBMED: 10330499.
RA Bertuzzi S., Porter F. D., Pitts A., Kumar M., Agulnick A., Wassif C., Westphal H.
RT Characterization of Lhx9, a novel LIM/homeobox gene expressed by the pioneer neurons in the mouse cerebral cortex
RL Mech. Dev. 81:193-198 (1999).
RN [7]; RE0046270.
RX PUBMED: 14560005.
RA Xu Z., Huang S., Chang L. S., Agulnick A. D., Brandt S. J.
RT Identification of a TAL1 target gene reveals a positive role for the LIM domain-binding protein Ldb1 in erythroid gene expression and differentiation
RL Mol. Cell. Biol. 23:7585-99 (2003).
RN [8]; RE0049146.
RX PUBMED: 16287841.
RA Schuh A. H., Tipping A. J., Clark A. J., Hamlett I., Guyot B., Iborra F. J., Rodriguez P., Strouboulis J., Enver T., Vyas P., Porcher C.
RT ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.
RL Mol. Cell. Biol. 25:10235-10250 (2005).
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