AC T10058
XX
ID T10058
XX
DT 30.12.2006 (created); sou.
DT 15.12.2014 (updated); ros.
CO Copyright (C), QIAGEN.
XX
FA Fli-1
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SY Erg-B; Fli-1.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009821 Fli1.
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CL C0016; ETS; 3.5.2.1.5.1.
XX
SZ 452 AA; 51.0 kDa (cDNA) (calc.), 51, 48 kDa (SDS)
XX
SQ MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ
SQ PVRVNVKREYDHMNGSRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNGPPPPNMTTN
SQ ERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATS
SQ AYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLNVKEDPSYDSVRRGAWNNNMNSGLNK
SQ SPLLGGSQTMGKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI
SQ TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF
SQ DFHGIAQALQPHPTETSMYKYPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAAS
SQ QYWTSPTAGIYPNPSVPRHPNTHVPSHLGSYY
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SC Swiss-Prot#P26323
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FT 114 198 
PF02198; Sterile alpha motif (SAM)/Pointed domain.
FT 114 198 
SM00251; SAM2_3.
FT 129 196 
POINTED domain of homology [4].
FT 280 363 
PF00178; Ets-domain.
FT 280 365 
SM00413; etsneu2.
FT 281 361 
PS50061; ETS_DOMAIN_3.
FT 283 351 
PS50140; HSF_ETS.
XX
IN T06598 AML-1; mouse, Mus musculus.
IN T08294 EKLF; mouse, Mus musculus.
IN T08988 Elf-1-isoform1; human, Homo sapiens.
IN T00305 GATA-1; mouse, Mus musculus.
IN T10217 GATA-1; Mammalia.
IN T08571 GATA-2-isoform1; human, Homo sapiens.
IN T02235 PEBP2alphaB1; mouse, Mus musculus.
XX
MX M08881 V$ETSLIKE_Q4.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
MX M02038 V$FLI1_01.
MX M07382 V$FLI1_Q5.
MX M01208 V$FLI1_Q6.
XX
BS R25964.
BS R19681.
BS R12965.
XX
DR TRANSPATH: MO000095468.
DR EMBL: X59421; MMFLI1.
DR UniProtKB: P26323; FLI1_MOUSE.
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RN [1]; RE0000282.
RX PUBMED: 8168137.
RA Golub T. R., Barker G. F., Lovett M., Gilliland D. G.
RT Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
RL Cell 77:307-316 (1994).
RN [2]; RE0000803.
RX PUBMED: 2044959.
RA Ben-David Y., Giddens E. B., Letwin K., Bernstein A.
RT Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1
RL Genes Dev. 5:908-918 (1991).
RN [3]; RE0002249.
RX PUBMED: 8502483.
RA Zhang L., Lemarchandel V., Romeo P.-H., Ben-David Y., Greer P., Bernstein A.
RT The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing`s sarcoma, encodes a transcriptional activator with DNA-binding specifities distinct from other Ets family members
RL Oncogene 8:1621-1630 (1993).
RN [4]; RE0005316.
RX PUBMED: 8223245.
RA Klaembt C.
RT The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells
RL Development 117:163-176 (1993).
RN [5]; RE0023642.
RX PUBMED: 12065417.
RA Gottgens B., Nastos A., Kinston S., Piltz S., Delabesse E. C., Stanley M., Sanchez M. J., Ciau-Uitz A., Patient R., Green A. R.
RT Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
RL EMBO J. 21:3039-3050 (2002).
RN [6]; RE0045775.
RX PUBMED: 12556498.
RA Starck J., Cohet N., Gonnet C., Sarrazin S., Doubeikovskaia Z., Doubeikovski A., Verger A., Duterque-Coquillaud M., Morle F.
RT Functional cross-antagonism between transcription factors FLI-1 and EKLF
RL Mol. Cell. Biol. 23:1390-402 (2003).
RN [7]; RE0049116.
RX PUBMED: 12379474.
RA Sarrazin S., Bonod-Bidaud C., Remy P., Mehlen P., Morle F.
RT Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death.
RL Biochim. Biophys. Acta 1592:123-127 (2002).
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