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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T10058 XX ID T10058 XX DT 30.12.2006 (created); sou. DT 15.12.2014 (updated); ros. CO Copyright (C), QIAGEN. XX FA Fli-1 XX SY Erg-B; Fli-1. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G009821 Fli1. XX CL C0016; ETS; 3.5.2.1.5.1. XX SZ 452 AA; 51.0 kDa (cDNA) (calc.), 51, 48 kDa (SDS) XX SQ MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ SQ PVRVNVKREYDHMNGSRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNGPPPPNMTTN SQ ERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATS SQ AYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLNVKEDPSYDSVRRGAWNNNMNSGLNK SQ SPLLGGSQTMGKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI SQ TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF SQ DFHGIAQALQPHPTETSMYKYPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAAS SQ QYWTSPTAGIYPNPSVPRHPNTHVPSHLGSYY XX SC Swiss-Prot#P26323 XX FT 114 198 PF02198; Sterile alpha motif (SAM)/Pointed domain. FT 114 198 SM00251; SAM2_3. FT 129 196 POINTED domain of homology [4]. FT 280 363 PF00178; Ets-domain. FT 280 365 SM00413; etsneu2. FT 281 361 PS50061; ETS_DOMAIN_3. FT 283 351 PS50140; HSF_ETS. XX IN T06598 AML-1; mouse, Mus musculus. IN T08294 EKLF; mouse, Mus musculus. IN T08988 Elf-1-isoform1; human, Homo sapiens. IN T00305 GATA-1; mouse, Mus musculus. IN T10217 GATA-1; Mammalia. IN T08571 GATA-2-isoform1; human, Homo sapiens. IN T02235 PEBP2alphaB1; mouse, Mus musculus. XX MX M08881 V$ETSLIKE_Q4. MX M00771 V$ETS_Q4. MX M00971 V$ETS_Q6. MX M02038 V$FLI1_01. MX M07382 V$FLI1_Q5. MX M01208 V$FLI1_Q6. XX BS R25964. BS R19681. BS R12965. XX DR TRANSPATH: MO000095468. DR EMBL: X59421; MMFLI1. DR UniProtKB: P26323; FLI1_MOUSE. XX RN [1]; RE0000282. RX PUBMED: 8168137. RA Golub T. R., Barker G. F., Lovett M., Gilliland D. G. RT Fusion of PDGf receptor beta to a novel ets-like gene, tel, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation RL Cell 77:307-316 (1994). RN [2]; RE0000803. RX PUBMED: 2044959. RA Ben-David Y., Giddens E. B., Letwin K., Bernstein A. RT Erythroleukemia induction by Friend murine leukemia virus: insertional activation of a new member of the ets gene family, Fli-1, closely linked to c-ets-1 RL Genes Dev. 5:908-918 (1991). RN [3]; RE0002249. RX PUBMED: 8502483. RA Zhang L., Lemarchandel V., Romeo P.-H., Ben-David Y., Greer P., Bernstein A. RT The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing`s sarcoma, encodes a transcriptional activator with DNA-binding specifities distinct from other Ets family members RL Oncogene 8:1621-1630 (1993). RN [4]; RE0005316. RX PUBMED: 8223245. RA Klaembt C. RT The Drosophila gene pointed encodes two ETS-like proteins which are involved in the development of the midline glial cells RL Development 117:163-176 (1993). RN [5]; RE0023642. RX PUBMED: 12065417. RA Gottgens B., Nastos A., Kinston S., Piltz S., Delabesse E. C., Stanley M., Sanchez M. J., Ciau-Uitz A., Patient R., Green A. R. RT Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors. RL EMBO J. 21:3039-3050 (2002). RN [6]; RE0045775. RX PUBMED: 12556498. RA Starck J., Cohet N., Gonnet C., Sarrazin S., Doubeikovskaia Z., Doubeikovski A., Verger A., Duterque-Coquillaud M., Morle F. RT Functional cross-antagonism between transcription factors FLI-1 and EKLF RL Mol. Cell. Biol. 23:1390-402 (2003). RN [7]; RE0049116. RX PUBMED: 12379474. RA Sarrazin S., Bonod-Bidaud C., Remy P., Mehlen P., Morle F. RT Caspase cleavage of the transcription factor FLI-1 during preB leukemic cell death. RL Biochim. Biophys. Acta 1592:123-127 (2002). XX //