AC T08571
XX
ID T08571
XX
DT 16.02.2006 (created); sou.
DT 30.11.2011 (updated); mka.
CO Copyright (C), QIAGEN.
XX
FA GATA-2-isoform1
XX
SY GATA-2; GATA-box binding factor 2; GATA2; NF-E1b (chick).
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004497 GATA2; HGNC: GATA2.
XX
CL C0003; CC (g).
XX
SZ 480 AA; 50.3 kDa (cDNA) (calc.).
XX
SQ MEVAPEQPGWMAHPAVLNAHDPDSHHPGLAHNYMEPAHVLPPDEVDVFFNHLDSQGNPYY
SQ ANPAHARAAVSYSPAHARLTGSQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSP
SQ FSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKE
SQ VSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQP
SQ ATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
SQ TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLW
SQ RRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKC
SQ MQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
XX
SC translated from EMBL:M68891
XX
FT 289 339 SM00401; ZnF_GATA.
FT 289 343 PS50114; GATA_ZN_FINGER_2.
FT 295 329 PF00320; GATA zinc finger.
FT 343 393 SM00401; ZnF_GATA.
FT 343 396 PS50114; GATA_ZN_FINGER_2.
FT 349 383 PF00320; GATA zinc finger.
XX
IN T08988 Elf-1-isoform1; human, Homo sapiens.
IN T10058 Fli-1; mouse, Mus musculus.
IN T08453 Hex; human, Homo sapiens.
IN T01516 Pit-1B; rat, Rattus norvegicus.
IN T09976 PU.1; human, Homo sapiens.
XX
MX M00076 V$GATA2_01.
MX M00348 V$GATA2_02.
MX M00349 V$GATA2_03.
MX M01877 V$GATA2_Q5.
MX M00203 V$GATA_C.
MX M00789 V$GATA_Q6.
XX
BS R20887.
BS R02797.
BS R20913.
BS R22479.
BS R20599.
BS R08261.
BS R21076.
BS R20583.
BS R31081.
XX
DR TRANSPATH: MO000074549.
DR EMBL: M68891; HSGATA.
DR UniProtKB: P23769;
XX
RN [1]; RE0023642.
RX PUBMED: 12065417.
RA Gottgens B., Nastos A., Kinston S., Piltz S., Delabesse E. C., Stanley M., Sanchez M. J., Ciau-Uitz A., Patient R., Green A. R.
RT Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.
RL EMBO J. 21:3039-3050 (2002).
RN [2]; RE0048127.
RX PUBMED: 10411939.
RA Zhang P., Behre G., Pan J., Iwama A., Wara-Aswapati N., Radomska H. S., Auron P. E., Tenen D. G., Sun Z.
RT Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.
RL Proc. Natl. Acad. Sci. USA 96:8705-8710 (1999).
RN [3]; RE0052827.
RX PUBMED: 15016828.
RA Minami T., Murakami T., Horiuchi K., Miura M., Noguchi T., Miyazaki J., Hamakubo T., Aird W. C., Kodama T.
RT Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling.
RL J. Biol. Chem. 279:20626-20635 (2004).
XX
//