AC T02334
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ID T02334
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DT 22.01.1998 (created); ili.
DT 28.08.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA FOG
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SY FOG; Fog1; Friend of GATA-1; Zfpm1; zinc finger protein, multitype 1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004485 Zfpm1.
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CL C0071; C2HC; 2.3.4.0.62.7.2.0.1.
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SF putative zinc fingers of C2H2-type [1];
SF P-rich regions, acidic regions [1];
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CN primary mast cells or macrophages (cell lines) grown from bone marrow [1].
EX allantois,red blood cell,,Theiler Stage 13; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX blood islands,red blood cell,,Theiler Stage 13; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX liver,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [1].
EX mouse, Mus musculus,erythroblast,,adult; detectable; immunohistochemistry / immunocytochemistry; protein; [1].
EX mouse, Mus musculus,megakaryocyte,,adult; detectable; immunohistochemistry / immunocytochemistry; protein; [1].
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FF acts as a cofactor for GATA-1 in erythroid and megakaryocytic differentiation [1];
FF interact specifically with the N-terminal zinc finger of GATA-1 to form a ternary complex on DNA [1];
FF activates transcription together with GATA-1 in synergistic fashion [1];
FF might influence the specificity and/or function of DNA binding by GATA-1 [1];
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IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T00305 GATA-1; mouse, Mus musculus.
IN T10217 GATA-1; Mammalia.
IN T06585 gfi1b; mouse, Mus musculus.
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MX M06755 V$FOG_01.
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BS R31712.
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DR TRANSPATH: MO000026331.
DR UniProtKB: O35615;
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RN [1]; RE0006528.
RX PUBMED: 9230307.
RA Tsang A. P., Visvader J. E., Turner C. A., Fujiwara Y., Yu C., Weiss M. J., Crossley M., Orkin S. H.
RT FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
RL Cell 90:109-119 (1997).
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