TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T27798 XX ID T27798 XX DT 10.03.2005 (created); nvo. DT 08.05.2015 (updated); jmh. CO Copyright (C), QIAGEN. XX FA Tal-1 XX SY SCL; TAL1. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T00207 E47; human, Homo sapiens. IN T10212 E47; Mammalia. IN T10217 GATA-1; Mammalia. IN T17995 GATA-2; Mammalia. IN T13822 GATA-3; Mammalia. IN T09513 HTF4; mouse, Mus musculus. IN T10018 Lyl-1; human, Homo sapiens. IN T23091 p300; Mammalia. IN T14264 RBTN2; Mammalia. IN T19337 RFP-alpha; human, Homo sapiens. IN T14622 sin3a; human, Homo sapiens. IN T08326 Sp1; Mammalia. XX MX M01034 V$EBOX_Q6_01. MX M00066 V$TAL1ALPHAE47_01. MX M00065 V$TAL1BETAE47_01. MX M00070 V$TAL1BETAITF2_01. MX M01591 V$TAL1_01. MX M00993 V$TAL1_Q6. MX M03804 V$TAL1_Q6_01. MX M07469 V$TALLIKE_Q6. XX BS R55983. XX DR TRANSPATH: MO000046495. XX RN [1]; RE0002932. RX PUBMED: 8289805. RA Hsu H.-L., Huang L., Tsan J. T., Funk W., Wright W. E., Hu J.-S., Kingston R. E., Baer R. RT Preferred sequences for DNA recognition by the TAL1 helix-loop-helix proteins RL Mol. Cell. Biol. 14:1256-1265 (1994). RN [2]; RE0021446. RX PUBMED: 10866689. RA Vitelli L., Condorelli G., Lulli V., Hoang T., Luchetti L., Croce C. M., Peschle C. RT A pentamer transcriptional complex including tal-1 and retinoblastoma protein downmodulates c-kit expression in normal erythroblasts RL Mol. Cell. Biol. 20:5330-5342 (2000). RN [3]; RE0025985. RX PUBMED: 9819382. RA Ono Y., Fukuhara N., Yoshie O. RT TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3. RL Mol. Cell. Biol. 18:6939-50 (1998). RN [4]; RE0027330. RX PUBMED: 11118214. RA Huang S., Qiu Y., Shi Y., Xu Z., Brandt S. J. RT P/CAF-mediated acetylation regulates the function of the basic helix-loop-helix transcription factor TAL1/SCL. RL EMBO J. 19:6792-6803 (2000). RN [5]; RE0034433. RX PUBMED: 12867998. RA Zeuner A., Eramo A., Testa U., Felli N., Pelosi E., Mariani G., Srinivasula S. M., Alnemri E. S., Condorelli G., Peschle C., De Maria R. RT Control of erythroid cell production via caspase-mediated cleavage of transcription factor SCL/Tal-1. RL Cell Death Differ. 10:905-13 (2003). RN [6]; RE0035566. RX PUBMED: 10688671. RA Huang S., Brandt S. J. RT mSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factor. RL Mol. Cell. Biol. 20:2248-2259 (2000). RN [7]; RE0035584. RX PUBMED: 10490830. RA Huang S., Qiu Y., Stein R. W., Brandt S. J. RT p300 functions as a transcriptional coactivator for the TAL1/SCL oncoprotein. RL Oncogene 18:4958-4967 (1999). RN [8]; RE0036544. RX PUBMED: 14749362. RA Lahlil R., Lecuyer E., Herblot S., Hoang T. RT SCL assembles a multifactorial complex that determines glycophorin A expression RL Mol. Cell. Biol. 24:1439-52 (2004). RN [9]; RE0038824. RX PUBMED: 7811994. RA Tanigawa T., Nicola N., McArthur G. A., Strasser A., Begley C. G. RT Differential regulation of macrophage differentiation in response to leukemia inhibitory factor/oncostatin-M/interleukin-6: the effect of enforced expression of the SCL transcription factor RL Blood 85:379-90 (1995). RN [10]; RE0039512. RX PUBMED: 9572395. RA Lister J. A., Baron M. H. RT Induction of basic helix-loop-helix protein-containing complexes during erythroid differentiation RL Gene Expr. 7:25-38 (1998). RN [11]; RE0042981. RX PUBMED: 9020185. RA Ono Y., Fukuhara N., Yoshie O. RT Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia (T-ALL) requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL RL J. Biol. Chem. 272:4576-81 (1997). RN [12]; RE0043453. RX PUBMED: 12569129. RA Ema M., Faloon P., Zhang W. J., Hirashima M., Reid T., Stanford W. L., Orkin S., Choi K., Rossant J. RT Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse RL Genes Dev. 17:380-93 (2003). RN [13]; RE0044219. RX PUBMED: 8265595. RA Chiba T., Nagata Y., Kishi A., Sakamaki K., Miyajima A., Yamamoto M., Engel J. D., Todokoro K. RT Induction of erythroid-specific gene expression in lymphoid cells RL Proc. Natl. Acad. Sci. USA 90:11593-7 (1993). RN [14]; RE0045778. RX PUBMED: 11209091. RA Caceres-Cortes J. R., Krosl G., Tessier N., Hugo P., Hoang T. RT Steel factor sustains SCL expression and the survival of purified CD34+ bone marrow cells in the absence of detectable cell differentiation RL Stem Cells 19:59-70 (2001). RN [15]; RE0045808. RX PUBMED: 7970731. RA Wadman I. A., Hsu H. L., Cobb M. H., Baer R. RT The MAP kinase phosphorylation site of TAL1 occurs within a transcriptional activation domain RL Oncogene 9:3713-6 (1994). RN [16]; RE0045848. RX PUBMED: 10751181. RA Faloon P., Arentson E., Kazarov A., Deng C. X., Porcher C., Orkin S., Choi K. RT Basic fibroblast growth factor positively regulates hematopoietic development RL Development 127:1931-41 (2000). RN [17]; RE0048230. RX PUBMED: 16007160. RA Bloor A. J., Kotsopoulou E., Hayward P., Champion B. R., Green A. R. RT RFP represses transcriptional activation by bHLH transcription factors. RL Oncogene 24:6729-6736 (2005). RN [18]; RE0049149. RX PUBMED: 14729962. RA Smith E. D., Xu Y., Tomson B. N., Leung C. G., Fujiwara Y., Orkin S. H., Crispino J. D. RT More than blood, a novel gene required for mammalian postimplantation development. RL Mol. Cell. Biol. 24:1168-1173 (2004). RN [19]; RE0049168. RX PUBMED: 15677454. RA Wen J., Huang S., Pack S. D., Yu X., Brandt S. J., Noguchi C. T. RT Tal1/SCL binding to pericentromeric DNA represses transcription. RL J. Biol. Chem. 280:12956-12966 (2005). XX //