AC T10018
XX
ID T10018
XX
DT 14.12.2006 (created); kau.
DT 19.07.2013 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA Lyl-1
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SY LYL1; lymphoblastic leukemia derived sequence 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003961 LYL1; HGNC: LYL1.
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CL C0010; bHLH.
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SZ 267 AA; 28.7 kDa (cDNA) (calc.).
XX
SQ MTEKAEMVCAPSPAPAPPPKPASPGPPQVEEVGHRGGSSPPRLPPGVPVISLGHSRPPGV
SQ AMPTTELGTLRPPLLQLSTLGTAPPTLALHYHPHPFLNSVYIGPAGPFSIFPSSRLKRRP
SQ SHCELDLAEGHQPQKVARRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLR
SQ LAMKYIGFLVRLLRDQAAALAAGPTPPGPRKRPVHRVPDDGPRRGSGRRAEAAARSQPAP
SQ PADPDGSPGGAARPIKMEQTALSPEVR
XX
SC Swiss-Prot#P12980
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FT 135 190 PS50888; HLH.
FT 138 190 PF00010; Helix-loop-helix DNA-binding domain.
FT 143 195 SM00353; finulus.
XX
IN T09920 CREB1; Mammalia.
IN T00204 E12; human, Homo sapiens.
IN T00207 E47; human, Homo sapiens.
IN T10212 E47; Mammalia.
IN T00432 ITF-1; human, Homo sapiens.
IN T14264 RBTN2; Mammalia.
IN T27798 Tal-1; Mammalia.
XX
MX M07469 V$TALLIKE_Q6.
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BS R24166.
XX
DR TRANSPATH: MO000094822.
DR EMBL: M22637;
DR EMBL: M22638;
DR UniProtKB: P12980;
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RN [1]; RE0003640.
RX PUBMED: 7957052.
RA Wadman I., Li J., Bash R. O., Forster A., Osada H., Rabbitts T. H., Baer R.
RT Specific in vivo association between the bHLH and LIM proteins implicated in human T cell leukemia
RL EMBO J. 13:4831-4839 (1994).
RN [2]; RE0003641.
RX PUBMED: 2752424.
RA Mellentin J. D., Smith S. D., Cleary M. L.
RT lyl-1, a novel gene involved by chromosomal translocation in T-cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif
RL Cell 58:77-83 (1989).
RN [3]; RE0003644.
RX PUBMED: 3162254.
RA Cleary M. L., Mellentin J. D., Spies J., Smith S. D.
RT Chromosomal translocation involving the beta T cell receptor gene in acute leukemia
RL J. Exp. Med. 167:682-687 (1988).
RN [4]; RE0012731.
RX PUBMED: 8628307.
RA Miyamoto A., Cui X., Naumovski L., Cleary M. L.
RT Helix-loop-helix proteins LYL1 and E2a form heterodimeric complexes with distinctive DNA-binding properties in hematolymphoid cells
RL Mol. Cell. Biol. 16:2394-2401 (1996).
XX
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