AC T10429
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ID T10429
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DT 17.04.2006 (created); kau.
DT 29.09.2015 (updated); mka.
CO Copyright (C), QIAGEN.
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FA PU.1
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SY 31 kDa transforming protein; Dis1; protooncogene pu.1; PU.1; SFFV proviral integration 1; SFFV proviral integration 1 protein; Sfpi-1; Sfpi1; Spi-1; Tcfpu.1; Tcfpu1; Tfpu.1; Transcription factor PU.1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G005728 Spi1.
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CL C0016; ETS; 3.5.2.5.1.1.
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SZ 272 AA; 31.3 kDa (cDNA) (calc.).
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SQ MLQACKMEGFSLTAPPSDDLVTYDSELYQRPMHDYYSFVGSDGESHSDHYWDFSAHHVHN
SQ NEFENFPENHFTELQSVQPPQLQQLYRHMELEQMHVLDTPMVPPHTGLSHQVSYMPRMCF
SQ PYQTLSPAHQQSSDEEEGERQSPPLEVSDGEADGLEPGPGLLHGETGSKKKIRLYQFLLD
SQ LLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYQKMARALRNYGKT
SQ GEVKKVKKKLTYQFSGEVLGRGGLAERRLPPH
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SC translated from EMBL:M32370
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IN T08461 c-Jun; human, Homo sapiens.
IN T09446 c-Jun; Mammalia.
IN T08574 C/EBPalpha; rat, Rattus norvegicus.
IN T09410 C/EBPbeta; Mammalia.
IN T10398 C/EBPdelta; Mammalia.
IN T00310 GATA-3; mouse, Mus musculus.
IN T08572 GATA-3; mouse, Mus musculus.
IN T09278 IRF-4-isoform1; mouse, Mus musculus.
IN T25008 pRb; Mammalia.
IN T10037 PU.1; Mammalia.
IN T14175 TBP; Mammalia.
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MX M00971 V$ETS_Q6.
MX M01172 V$PU1_Q4.
MX M00658 V$PU1_Q6.
MX M02896 V$SFPI1_04.
MX M01203 V$SPI1_01.
MX M02043 V$SPI1_02.
MX M02031 V$SPI1_Q5.
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BS R26043.
BS R26044.
BS R26045.
BS R26046.
BS R26047.
BS R26048.
BS R26049.
BS R26050.
BS R26051.
BS R26052.
BS R26053.
BS R26054.
BS R26055.
BS R26056.
BS R26057.
BS R26058.
BS R26059.
BS R26060.
BS R26061.
BS R26062.
BS R26063.
BS R26064.
BS R26065.
BS R26066.
BS R26067.
BS R26068.
BS R26069.
BS R26070.
BS R26071.
BS R26072.
BS R26073.
BS R26074.
BS R26075.
BS R26076.
BS R26077.
BS R26078.
BS R26079.
BS R26080.
BS R26081.
BS R26082.
BS R26083.
BS R26084.
BS R26085.
BS R26086.
BS R26087.
BS R26088.
BS R26089.
BS R26090.
BS R26091.
BS R26092.
BS R26093.
BS R26094.
BS R26095.
BS R26096.
BS R26097.
BS R26098.
BS R26099.
BS R25964.
BS R33634.
BS R22316.
BS R21103.
BS R21108.
BS R20444.
BS R21097.
BS R14489.
BS R28115.
BS R28116.
BS R21112.
BS R22548.
BS R27495.
BS R27496.
BS R27497.
BS R27500.
BS R27501.
BS R26037.
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DR TRANSPATH: MO000080087.
DR TRANSCOMPEL: C00562.
DR EMBL: M32370; MMPU1.
DR UniProtKB: P17433; PU1_MOUSE.
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RN [1]; RE0016555.
RX PUBMED: 9551977.
RA Perkel J. M., Atchison M. L.
RT A two-step mechanism for recruitment of Pip by PU.1
RL J. Immunol. 160:241-252 (1998).
RN [2]; RE0023165.
RX PUBMED: 10801783.
RA Yang Z., Wara-Aswapati N., Chen C., Tsukada J., Auron P. E.
RT NF-IL6 (C/EBPbeta ) vigorously activates il1b gene expression via a Spi-1 (PU.1) protein-protein tether.
RL J. Biol. Chem. 275:21272-21277 (2000).
RN [3]; RE0048134.
RX PUBMED: 10196196.
RA Rao S., Matsumura A., Yoon J., Simon M. C.
RT SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1.
RL J. Biol. Chem. 274:11115-11124 (1999).
RN [4]; RE0048140.
RX PUBMED: 14592421.
RA Hirose S., Nishizumi H., Sakano H.
RT Pub, a novel PU.1 binding protein, regulates the transcriptional activity of PU.1.
RL Biochem. Biophys. Res. Commun. 311:351-360 (2003).
RN [5]; RE0048146.
RX PUBMED: 15963784.
RA Chang H. C., Zhang S., Thieu V. T., Slee R. B., Bruns H. A., Laribee R. N., Klemsz M. J., Kaplan M. H.
RT PU.1 expression delineates heterogeneity in primary Th2 cells.
RL Immunity 22:693-703 (2005).
RN [6]; RE0048459.
RX PUBMED: 12091339.
RA Reddy V. A., Iwama A., Iotzova G., Schulz M., Elsasser A., Vangala R. K., Tenen D. G., Hiddemann W., Behre G.
RT Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions.
RL Blood 100:483-490 (2002).
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