AC T00310
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ID T00310
XX
DT 26.01.1993 (created); hse.
DT 14.06.2016 (updated); vis.
CO Copyright (C), QIAGEN.
XX
FA GATA-3
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SY GATA-3; GATA3.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G004546 Gata3.
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CL C0004; CC; 2.2.1.1.3.
XX
SF 2 zinc finger motifs;
SF pI 9.89;
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CP BW5147.3 and C1300 cells [5]; E9.5 cells [8].
EX adrenal cortex,,,Theiler Stage 23; none; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX adrenal medulla,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX adrenal medulla,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX blood vessel,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX blood vessel,red blood cell,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX brain,,,adult; none; Northern blot; total RNA; [4].
EX brain,,,fetal; detectable; Northern blot; total RNA; [4].
EX collecting tubules,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX diencephalon,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX diencephalon,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX diencephalon,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX dorsal root ganglion,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX dorsal root ganglion,,,Theiler Stage 20; none; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX ectoplacental cone,,,Theiler Stage 12; high; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX epidermis,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX epidermis,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX epidermis,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX epidermis,,,Theiler Stage 25; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX epithelium of cochlear duct,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX epithelium of cochlear duct,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX eye and related structures (right and left),,,Theiler Stage 16; low; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX facio-acoustic complex [VII VIII],,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX future pons,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX future pons,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX ganglion of sympathetic trunk,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX ganglion of sympathetic trunk,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX glomerulus,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX heart,,,adult; none; Northern blot; total RNA; [4].
EX heart,red blood cell,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX inner root sheath,pluripotent cell,,Theiler Stage 25; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX lens fibers,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX lens fibers,,,Theiler Stage 23; none; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX liver,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX liver,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX liver,,,adult; none; Northern blot; total RNA; [4].
EX mesencephalon,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX mesencephalon,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX mesencephalon,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX mesencephalon,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX mesenchyme of periorbital region,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX mesonephros,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX mouse, Mus musculus,,,Theiler Stage 16; none; Northern blot; total RNA; [4].
EX mouse, Mus musculus,B-lymphocyte,,adult; none; Northern blot; total RNA; [4].
EX mouse, Mus musculus,T-lymphocyte,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX mouse, Mus musculus,undifferentiated embryonic stem cell,,fetal; none; Northern blot; total RNA; [4].
EX neural crest of otocyst,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX ovary,,,adult; none; Northern blot; total RNA; [4].
EX periorbital region,mesenchyme cell,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX periorbital region,mesenchyme cell,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX periorbital region,mesenchyme cell,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX placenta,,,adult; detectable; Northern blot; total RNA; [4].
EX pons,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX pons,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX primary palate,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX retina,pigmented cell,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX rhombencephalon,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX skin,,,Theiler Stage 24; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX somite,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX spinal cord,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX spinal cord,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX spinal cord,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX spinal cord,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX spinal cord,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX spinal cord,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX telencephalon,,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX testis (right and left),,,adult; none; Northern blot; total RNA; [4].
EX thymus,,,Theiler Stage 20; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX thymus,,,Theiler Stage 23; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX trigeminal ganglion [V],,,Theiler Stage 16; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX trophectoderm,trophoblast cell,,Theiler Stage 12; high; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX uterus,,,adult; none; Northern blot; total RNA; [4].
EX vibrissae,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [6].
EX vitelline vein,,,Theiler Stage 19; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX vomeronasal organ,,,Theiler Stage 22; detectable; RNA-in situ hybridization (not further specified); RNA (undefined); [11].
EX whisker follicle,,,Theiler Stage 20; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
EX whisker follicle,,,Theiler Stage 23; high; RNA-in situ hybridization (not further specified); RNA (undefined); [10].
XX
IN T08664 C/EBPalpha; Mammalia.
IN T09410 C/EBPbeta; Mammalia.
IN T00305 GATA-1; mouse, Mus musculus.
IN T01412 IRF-4; mouse, Mus musculus.
IN T01947 NFATc1; mouse, Mus musculus.
IN T15616 NFATc2; mouse, Mus musculus.
IN T00702 PU.1; mouse, Mus musculus.
IN T10429 PU.1; mouse, Mus musculus.
IN T04210 Smad3; mouse, Mus musculus.
XX
MX M00077 V$GATA3_01.
MX M00350 V$GATA3_02.
MX M00351 V$GATA3_03.
MX M02859 V$GATA3_05.
MX M08997 V$GATA3_12.
MX M01878 V$GATA3_Q4.
MX M00203 V$GATA_C.
MX M00789 V$GATA_Q6.
XX
BS R02158.
BS R39832.
BS R30290.
BS R22878.
BS R73150.
BS R14572.
BS R40045.
BS R30629.
BS R08264.
BS R73616.
BS R08270.
BS R08271.
BS R08272.
BS R08276.
XX
DR TRANSPATH: MO000005570.
DR UniProtKB: P23772;
XX
RN [1]; RE0000167.
RX PUBMED: 2225071.
RA Orkin S. H.
RT Globin gene regulation and switching: Circa 1990
RL Cell 63:665-672 (1990).
RN [2]; RE0000451.
RX PUBMED: 1827068.
RA Ho I.-C., Vorhees P., Marin N., Oakley B. K., Tsai S.-F., Orkin S. H., Leiden J. M.
RT Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene
RL EMBO J. 10:1187-1192 (1991).
RN [3]; RE0000452.
RX PUBMED: 2050118.
RA Joulin V., Bouries D., Eleouet J.-F., Labastie M.-C., Chretien S., Mattei M.-G., Romeo P.-H.
RT A t-cell specific TCR delta DNA binding protein is a member of the human GATA family
RL EMBO J. 10:1809-1816 (1991).
RN [4]; RE0001473.
RX PUBMED: 2017177.
RA Ko L. J., Yamamoto M., Leonard M. W., George K. M., Ting P., Engel J. D.
RT Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer
RL Mol. Cell. Biol. 11:2778-2784 (1991).
RN [5]; RE0007082.
RX PUBMED: 8114750.
RA Yang Z., Gu L., Romeo P.-H., Bories D., Motohashi H., Yamamoto M., Engel J. D.
RT Human GATA-3 trans-activation, DNA-binding, and nuclear localization activities are organized into distinct structural domains
RL Mol. Cell. Biol. 14:2201-2212 (1994).
RN [6]; RE0023529.
RX PUBMED: 12923059.
RA Kaufman C. K., Zhou P., Pasolli H. A., Rendl M., Bolotin D., Lim K. C., Dai X., Alegre M. L., Fuchs E.
RT GATA-3: an unexpected regulator of cell lineage determination in skin.
RL Genes Dev. 17:2108-2122 (2003).
RN [7]; RE0036169.
RX PUBMED: 15632071.
RA Tong Q., Tsai J., Tan G., Dalgin G., Hotamisligil G. S.
RT Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation.
RL Mol. Cell. Biol. 25:706-715 (2005).
RN [8]; RE0051927.
RX PUBMED: 17213386.
RA Sher N., Yivgi-Ohana N., Orly J.
RT Transcriptional regulation of the cholesterol side chain cleavage cytochrome P450 gene (CYP11A1) revisited: binding of GATA, cyclic adenosine 3',5'-monophosphate response element-binding protein and activating protein (AP)-1 proteins to a distal novel cluster of cis-regulatory elements potentiates AP-2 and steroidogenic factor-1-dependent gene expression in the rodent placenta and ovary.
RL Mol. Endocrinol. 21:948-962 (2007).
RN [9]; RE0063363.
RX PUBMED: 18454155.
RA Krishnamoorthy N., Oriss T. B., Paglia M., Fei M., Yarlagadda M., Vanhaesebroeck B., Ray A., Ray P.
RT Activation of c-Kit in dendritic cells regulates T helper cell differentiation and allergic asthma.
RL Nat. Med. 14:565-573 (2008).
RN [10]; RE0017663.
RX PUBMED: 1343100.
RA Oosterwegel M., Timmerman J., Leiden J., Clevers H.
RT Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis.
RL Dev. Immunol. 3:1-11 (1992).
RN [11]; RE0017638.
RX PUBMED: 7956841.
RA George K. M., Leonard M. W., Roth M. E., Lieuw K. H., Kioussis D., Grosveld F., Engel J. D.
RT Embryonic expression and cloning of the murine GATA-3 gene.
RL Development 120:2673-2686 (1994).
XX
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