AC T08574
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ID T08574
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DT 16.02.2006 (created); sou.
DT 30.09.2015 (updated); sup.
CO Copyright (C), QIAGEN.
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FA C/EBPalpha
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SY BPc; C/EBP; C/EBP alpha; C/EBPalpha; CBP; CCAAT/enhancer binding protein alpha; CEBPA; EBP20; LF-H3beta.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G001192 Cebpa.
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CL C0008; bZIP; 1.1.8.1.1.
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CP stellate cells [14].
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IN T09335 ATF-2-isoform2; rat, Rattus norvegicus.
IN T01382 ATF-2; rat, Rattus norvegicus.
IN T00308 GATA-2; human, Homo sapiens.
IN T09048 HNF-1alpha; mouse, Mus musculus.
IN T00890 HNF-1beta; mouse, Mus musculus.
IN T00707 Pit-1; rat, Rattus norvegicus.
IN T10429 PU.1; mouse, Mus musculus.
IN T00818 TFIIB; human, Homo sapiens.
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MX M00116 V$CEBPA_01.
MX M07412 V$CEBPA_04.
MX M07037 V$CEBPA_Q4.
MX M01866 V$CEBPA_Q6.
MX M00159 V$CEBP_01.
MX M00201 V$CEBP_C.
MX M00190 V$CEBP_Q2.
MX M00912 V$CEBP_Q2_01.
MX M00770 V$CEBP_Q3.
MX M00249 V$CHOP_01.
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BS R00207.
BS R16635.
BS R69689.
BS R56143.
BS R56146.
BS R19618.
BS R21124.
BS R25910.
BS R25911.
BS R34357.
BS R20304.
BS R20305.
BS R20306.
BS R21707.
BS R26364.
BS R23185.
BS R28354.
BS R37306.
BS R58214.
BS R58216.
BS R58217.
BS R58218.
BS R58222.
BS R58225.
BS R58226.
BS R58229.
BS R58230.
BS R58231.
BS R01817.
BS R21634.
BS R08130.
BS R23215.
BS R21609.
BS R31314.
BS R31318.
BS R34373.
BS R00096.
BS R00097.
BS R61587.
BS R18561.
BS R18589.
BS R20485.
BS R38355.
BS R21782.
BS R34536.
BS R34686.
BS R73120.
BS R31189.
BS R21384.
BS R65360.
BS R41901.
BS R35688.
BS R29469.
BS R23201.
BS R23202.
BS R23205.
BS R23206.
BS R23207.
BS R23208.
BS R23209.
BS R23210.
BS R23212.
BS R23213.
BS R23214.
BS R26746.
BS R26977.
BS R63984.
BS R01688.
BS R37816.
BS R39325.
BS R39331.
BS R16332.
BS R20458.
BS R28513.
BS R28514.
BS R25899.
BS R25887.
BS R25888.
BS R25890.
BS R25896.
BS R34926.
BS R65273.
BS R65274.
BS R65275.
BS R36358.
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DR TRANSPATH: MO000074568.
DR TRANSCOMPEL: C00554.
DR TRANSCOMPEL: C00573.
DR TRANSCOMPEL: C00631.
DR UniProtKB: P05554;
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RN [1]; RE0006251.
RX PUBMED: 7556073.
RA Nerlov C., Ziff E. B.
RT CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells
RL EMBO J. 14:4318-4328 (1995).
RN [2]; RE0030288.
RX PUBMED: 12695546.
RA Rodriguez-Antona C., Bort R., Jover R., Tindberg N., Ingelman-Sundberg M., Gomez-Lechon M. J., Castell J. V.
RT Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.
RL Mol. Pharmacol. 63:1180-9 (2003).
RN [3]; RE0036169.
RX PUBMED: 15632071.
RA Tong Q., Tsai J., Tan G., Dalgin G., Hotamisligil G. S.
RT Interaction between GATA and the C/EBP family of transcription factors is critical in GATA-mediated suppression of adipocyte differentiation.
RL Mol. Cell. Biol. 25:706-715 (2005).
RN [4]; RE0042688.
RX PUBMED: 11684017.
RA Wang H., Iakova P., Wilde M., Welm A., Goode T., Roesler W. J., Timchenko N. A.
RT C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4
RL Mol. Cell 8:817-28 (2001).
RN [5]; RE0047928.
RX PUBMED: 12554785.
RA Day R. N., Voss T. C., Enwright JF 3. r. d., Booker C. F., Periasamy A., Schaufele F.
RT Imaging the localized protein interactions between Pit-1 and the CCAAT/enhancer binding protein alpha in the living pituitary cell nucleus.
RL Mol. Endocrinol. 17:333-345 (2003).
RN [6]; RE0047993.
RX PUBMED: 12873812.
RA Tinel M., Berson A., Elkahwaji J., Cresteil T., Beaune P., Pessayre D.
RT Downregulation of cytochromes P450 in growth-stimulated rat hepatocytes: role of c-Myc induction and impaired C/EBP binding to DNA.
RL J. Hepatology 39:171-178 (2003).
RN [7]; RE0048324.
RX PUBMED: 9139739.
RA Shuman J. D., Cheong J., Coligan J. E.
RT ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation.
RL J. Biol. Chem. 272:12793-12800 (1997).
RN [8]; RE0048349.
RX PUBMED: 11356826.
RA Hong S., Park S. J., Kong H. J., Shuman J. D., Cheong J.
RT Functional interaction of bZIP proteins and the large subunit of replication factor C in liver and adipose cells.
RL J. Biol. Chem. 276:28098-28105 (2001).
RN [9]; RE0048459.
RX PUBMED: 12091339.
RA Reddy V. A., Iwama A., Iotzova G., Schulz M., Elsasser A., Vangala R. K., Tenen D. G., Hiddemann W., Behre G.
RT Granulocyte inducer C/EBPalpha inactivates the myeloid master regulator PU.1: possible role in lineage commitment decisions.
RL Blood 100:483-490 (2002).
RN [10]; RE0048507.
RX PUBMED: 16908544.
RA Demarco I. A., Voss T. C., Booker C. F., Day R. N.
RT Dynamic Interactions between Pit-1 and C/EBP alpha in the Pituitary Cell Nucleus.
RL Mol. Cell. Biol. 26:8087-8098 (2006).
RN [11]; RE0048551.
RX PUBMED: 16254192.
RA Paz-Priel I., Cai D. H., Wang D., Kowalski J., Blackford A., Liu H., Heckman C. A., Gombart A. F., Koeffler H. P., Boxer L. M., Friedman A. D.
RT CCAAT/enhancer binding protein alpha (C/EBPalpha) and C/EBPalpha myeloid oncoproteins induce bcl-2 via interaction of their basic regions with nuclear factor-kappaB p50.
RL Mol. Cancer Res. 3:585-596 (2005).
RN [12]; RE0048565.
RX PUBMED: 16735515.
RA Sato Y., Miyake K., Kaneoka H., Iijima S.
RT Sumoylation of CCAAT/enhancer-binding protein alpha and its functional roles in hepatocyte differentiation.
RL J. Biol. Chem. 281:21629-21639 (2006).
RN [13]; RE0048826.
RX PUBMED: 16321657.
RA Staloch L. J., Divine J. K., Witten J. T., Simon T. C.
RT C/EBP and Cdx family factors regulate liver fatty acid binding protein transgene expression in the small intestinal epithelium.
RL Biochim. Biophys. Acta 1731:168-178 (2005).
RN [14]; RE0050467.
RX PUBMED: 10871045.
RA Attard F. A., Wang L., Potter J. J., Rennie-Tankersley L., Mezey E.
RT CCAAT/enhancer binding protein beta mediates the activation of the murine alpha1(I) collagen promoter by acetaldehyde.
RL Arch. Biochem. Biophys. 378:57-64 (2000).
RN [15]; RE0053527.
RX PUBMED: 17094771.
RA Park M. J., Kong H. J., Kim H. Y., Kim H. H., Kim J. H., Cheong J. H.
RT Transcriptional repression of the gluconeogenic gene PEPCK by the orphan nuclear receptor SHP through inhibitory interaction with C/EBPalpha.
RL Biochem. J. 402:567-574 (2007).
RN [16]; RE0053554.
RX PUBMED: 16807249.
RA Qiao L., MacDougald O. A., Shao J.
RT CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase.
RL J. Biol. Chem. 281:24390-24397 (2006).
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