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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T00890 XX ID T00890 XX DT 26.01.1993 (created); hse. DT 05.07.2013 (updated); uat. CO Copyright (C), QIAGEN. XX FA HNF-1beta XX SY HNF-1B; LF-B3; LFB3; TCF-2; vHNF-1; vHNF1. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G013738 Hnf1b. XX CL C0007; POU; 3.1.10.7.2. XX CP kidney, lung, (liver, ovary, intestine, stomach: weak mRNA-signal), epithel of endo- and mesodermal origin. CN spleen, brain, heart, thymus. XX FF induced in F9 cells by retinoic acid, max. after 24 hours [2]; XX IN T08574 C/EBPalpha; rat, Rattus norvegicus. IN T09410 C/EBPbeta; Mammalia. IN T23083 Cdx-1; Mammalia. IN T09327 Cdx-2; human, Homo sapiens. IN T00368 HNF-1alpha-A; human, Homo sapiens. IN T00369 HNF-1alpha; rat, Rattus norvegicus. IN T01211 HNF-1alpha; mouse, Mus musculus. XX MX M01425 V$HNF1B_01. MX M03826 V$HNF1B_Q6. MX M03872 V$HNF1B_Q6_01. MX M00790 V$HNF1_Q6. MX M01011 V$HNF1_Q6_01. MX M00646 V$LFA1_Q6. XX BS R02193. BS R38656. BS R38657. BS R32185. BS R33016. BS R32896. BS R40124. BS R40127. BS R00439. BS R72324. BS R02175. XX DR TRANSPATH: MO000045338. DR UniProtKB: P27889; XX RN [1]; RE0000456. RX PUBMED: 1673925. RA de Simone V., de Magistris L., Lazzaro D., Gerstner J., Monaci P., Nicosia A., Cortese R. RT LFB3, a heterodimer-forming homeoprotein of the LFB1 family, is expressed in specialized epithelia RL EMBO J. 10:1435-1443 (1991). RN [2]; RE0000510. RX PUBMED: 2065662. RA Kuo C. J., Mendel D. B., Hansen L. P., Crabtree G. R. RT Independent regulation of HNF-1alpha and HNF-1beta by retinoic acid in F9 teratocarcinoma cells RL EMBO J. 10:2231-2236 (1991). RN [3]; RE0000675. RX PUBMED: 2044952. RA Mendel D. B., Hansen L. P., Graves M. K., Conley P. B., Crabtree G. R. RT HNF-1alpha and HNF-1beta (vHNF-1) share dimerization and homeo domains, but not activation domains, and form heterodimers in vitro RL Genes Dev. 5:1042-1056 (1991). RN [4]; RE0004755. RX PUBMED: 8388098. RA Menoud P.-A., Matthies R., Hofsteenge J., Nagamine Y. RT Purification and cDNA cloning of a transcription factor which functionally cooperates within a cAMP regulatory unit in the porcine uPA gene RL Nucleic Acids Res. 21:1845-1852 (1993). RN [5]; RE0048826. RX PUBMED: 16321657. RA Staloch L. J., Divine J. K., Witten J. T., Simon T. C. RT C/EBP and Cdx family factors regulate liver fatty acid binding protein transgene expression in the small intestinal epithelium. RL Biochim. Biophys. Acta 1731:168-178 (2005). XX //