AC T09327
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ID T09327
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DT 19.09.2006 (created); jay.
DT 25.08.2014 (updated); jmh.
CO Copyright (C), QIAGEN.
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FA Cdx-2
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SY caudal homolog homeobox protein 2; Cdx-2; Cdx-3; CDX3; IPF-1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002226 CDX2; HGNC: CDX2.
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CL C0006; homeo.
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SZ 313 AA; 33.5 kDa (cDNA) (calc.), 37 kDa (SDS) [1]
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SQ MYVSYLLDKDVSMYPSSVRHSGGLNLAPQNFVSPPQYPDYGGYHVAAAAAAAANLDSAQS
SQ PGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHPH
SQ HHPHHPAAAPSCASGLLQTLNPGPPGPAATAAAEQLSPGGQRRNLCEWMRKPAQQSLGSQ
SQ VKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAK
SQ ERKINKKKLQQQQQQQPPQPPPPPPQPPQPQPGPLRSVPEPLSPVSSLQASVSGSVPGVL
SQ GPTGGVLNPTVTQ
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SC translated from EMBL:U51096
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FT 13 180 
PF04731; Caudal_act.
FT 184 244 
PS50071; HOMEOBOX_2.
FT 186 248 
SM00389; HOX_1.
FT 187 243 
PF00046; Homeobox.
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IN T09048 HNF-1alpha; mouse, Mus musculus.
IN T00890 HNF-1beta; mouse, Mus musculus.
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MX M01449 V$CDX2_01.
MX M00729 V$CDX2_Q5.
MX M01659 V$CDX2_Q5_01.
MX M02087 V$CDX2_Q5_02.
MX M07416 V$CDX2_Q6.
MX M07378 V$CDX_Q4.
MX M00991 V$CDX_Q5.
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BS R32349.
BS R36201.
BS R32350.
BS R36255.
BS R28996.
BS R08886.
BS R59396.
BS R59401.
BS R14709.
BS R23671.
BS R63581.
BS R04239.
BS R40020.
BS R40022.
BS R40023.
BS R40024.
BS R40025.
BS R40027.
BS R18914.
BS R18910.
BS R39301.
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DR TRANSPATH: MO000087495.
DR EMBL: AF007884;
DR EMBL: AF007885;
DR EMBL: AF007886;
DR EMBL: U51096;
DR UniProtKB: Q99626;
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RN [1]; RE0014403.
RX PUBMED: 9148757.
RA Troelsen J. T., Mitchelmore C., Spodsberg N., Jensen A. M., Noren O., Sjoestroem H.
RT Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2
RL Biochem. J. 322:833-838 (1997).
RN [2]; RE0014425.
RX PUBMED: 10070050.
RA Swenson E. S., Mann E. A., Jump M. L., Giannella R. A.
RT Hepatocyte nuclear factor-4 regulates intestinal expression of the guanylin/heat-stable toxin receptor
RL Am. J. Physiol. 276:G728-G736 (1999).
RN [3]; RE0015723.
RX PUBMED: 7698771.
RA German M. S., Wang J., Fernald A.A., Espinosa R., Le Beau M. M., Bell G.I.
RT Localization of the genes encoding two transcription factors, LMX1 and CDX3, regulating insulin gene expression to human chromosomes 1 and 13
RL Genomics 24:403-404 (1994).
RN [4]; RE0038781.
RX PUBMED: 12855703.
RA Isshiki S., Kudo T., Nishihara S., Ikehara Y., Togayachi A., Furuya A., Shitara K., Kubota T., Watanabe M., Kitajima M., Narimatsu H.
RT Lewis type 1 antigen synthase (beta3Gal-T5) is transcriptionally regulated by homeoproteins
RL J. Biol. Chem. 278:36611-20 (2003).
RN [5]; RE0048826.
RX PUBMED: 16321657.
RA Staloch L. J., Divine J. K., Witten J. T., Simon T. C.
RT C/EBP and Cdx family factors regulate liver fatty acid binding protein transgene expression in the small intestinal epithelium.
RL Biochim. Biophys. Acta 1731:168-178 (2005).
RN [6]; RE0052419.
RX PUBMED: 17468517.
RA Saegusa M., Hashimura M., Kuwata T., Hamano M., Wani Y., Okayasu I.
RT A functional role of Cdx2 in beta-catenin signaling during transdifferentiation in endometrial carcinomas.
RL Carcinogenesis 28:1885-1892 (2007).
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