AC T10308
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ID T10308
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DT 08.03.2007 (created); nta.
DT 07.03.2012 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA ZNF76-isoform1
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SY zinc finger protein 76.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G002942 ZNF76; HGNC: znf76.
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CL C0001; CH; 2.3.3.28.1.1.
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SZ 515 AA; 56.3 kDa (calc.).
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SQ MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQ
SQ PVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLE
SQ DLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAH
SQ HLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSG
SQ DLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSAT
SQ NYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYNDHVVHTHCKPYTCSTCGKTYRQTSTL
SQ AMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQ
SQ VAMVTEEDGAPQVALITQDGAQQVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAV
SQ QLEEQQTLEEAINVATAAMQQGAVTLETTVSESGC
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SC translated from EMBL #M91592
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FT 78 505 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 164 372 
zinc finger domain [1].
FT 165 189 
PF00096; zf-C2H2.
FT 165 189 
SM00355; c2h2final6.
FT 165 194 
PS50157; ZINC_FINGER_C2H2_2.
FT 195 219 
PF00096; zf-C2H2.
FT 195 219 
SM00355; c2h2final6.
FT 195 224 
PS50157; ZINC_FINGER_C2H2_2.
FT 225 249 
PF00096; zf-C2H2.
FT 225 249 
SM00355; c2h2final6.
FT 225 254 PS50157; ZINC_FINGER_C2H2_2.
FT 255 279 PF00096; zf-C2H2.
FT 255 279 SM00355; c2h2final6.
FT 255 284 PS50157; ZINC_FINGER_C2H2_2.
FT 285 309 PF00096; zf-C2H2.
FT 285 309 SM00355; c2h2final6.
FT 285 314 PS50157; ZINC_FINGER_C2H2_2.
FT 315 341 SM00355; c2h2final6.
FT 315 344 PS50157; ZINC_FINGER_C2H2_2.
FT 345 368 PF00096; zf-C2H2.
FT 345 368 SM00355; c2h2final6.
FT 345 373 PS50157; ZINC_FINGER_C2H2_2.
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IN T14175 TBP; Mammalia.
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BS R11769.
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DR TRANSPATH: MO000102305.
DR EMBL: M91592;
DR UniProtKB: P36508-2;
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RN [1]; RE0017375.
RX PUBMED: 9705341.
RA Myslinski E., Krol A., Carbon P.
RT ZNF76 and ZNF143 are two human homologs of the transcriptional activator Staf.
RL J. Biol. Chem. 273:21998-22006 (1998).
RN [2]; RE0017376.
RX PUBMED: 1427894.
RA Ragoussis J., Senger G., Mockridge I., Sanseau P., Ruddy S., Dudley K., Sheer D., Trowsdale J.
RT A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the t-complex gene tcp-11.
RL Genomics 14:673-679 (1992).
RN [3]; RE0050020.
RX PUBMED: 16337145.
RA Zheng G., Yang Y. C.
RT Acetylation and alternative splicing regulate ZNF76-mediated transcription.
RL Biochem. Biophys. Res. Commun. 339:1069-1075 (2006).
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