AC T09269
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ID T09269
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DT 25.08.2006 (created); jag.
DT 11.10.2011 (updated); sla.
CO Copyright (C), QIAGEN.
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FA Spi-B-isoform1
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SY Spi-B.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003952 SPIB; HGNC: SPIB.
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CL C0016; ETS; 3.5.2.5.2.1.
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SZ 262 AA; 28.8 kDa (cDNA) (calc.).
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SQ MLALEAAQLDGPHFSCLYPDGVFYDLDSCKHSSYPDSEGAPDSLWDWTVAPPVPATPYEA
SQ FDPAAAAFSHPQAAQLCYEPPTYSPAGNLELAPSLEAPGPGLPAYPTENFASQTLVPPAY
SQ APYPSPVLSEEEDLPLDSPALEVSDSESDEALVAGPEGKGSEAGTRKKLRLYQFLLGLLT
SQ RGDMRECVWWVEPGAGVFQFSSKHKELLARRWGQQKGNRKRMTYQKLARALRNYAKTGEI
SQ RKVKRKLTYQFDSALLPAVRRA
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SC Swiss-Prot#Q01892-1
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FT 168 254 
PF00178; Ets-domain.
FT 168 256 
SM00413; etsneu2.
FT 169 252 
PS50061; ETS_DOMAIN_3.
FT 171 243 
PS50140; HSF_ETS.
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IN T09446 c-Jun; Mammalia.
IN T08499 CBP; mouse, Mus musculus.
IN T21984 p300; human, Homo sapiens.
IN T10037 PU.1; Mammalia.
IN T19590 Spi-B; Mammalia.
IN T14175 TBP; Mammalia.
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MX M00971 V$ETS_Q6.
MX M02076 V$SPIB_03.
MX M03851 V$SPIB_Q3.
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BS R03675.
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DR TRANSPATH: MO000085714.
DR EMBL: X66079; HSSPIBMR.
DR UniProtKB: Q01892-1;
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RN [1]; RE0001748.
RX PUBMED: 1406622.
RA Ray D., Bosselut R., Ghysdael J., Mattel M.-G., Tavitian A., Moreau-Gachelin F.
RT Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1
RL Mol. Cell. Biol. 12:4297-4304 (1992).
RN [2]; RE0023723.
RX PUBMED: 11864910.
RA Yamamoto H., Kihara-Negishi F., Yamada T., Suzuki M., Nakano T., Oikawa T.
RT Interaction between the hematopoietic Ets transcription factor Spi-B and the coactivator CREB-binding protein associated with negative cross-talk with c-Myb.
RL Cell Growth Differ. 13:69-75 (2002).
RN [3]; RE0048134.
RX PUBMED: 10196196.
RA Rao S., Matsumura A., Yoon J., Simon M. C.
RT SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1.
RL J. Biol. Chem. 274:11115-11124 (1999).
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