TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T16474 XX ID T16474 XX DT 10.03.2005 (created); nvo. DT 11.09.2009 (updated); apk. CO Copyright (C), QIAGEN. XX FA HMGB1 XX SY high-mobility group box 1; HMG1; HMG3; HMGB1; SBP-1. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10890 Oct3; Mammalia. IN T16759 p73; Mammalia. IN T24182 PR; Mammalia. IN T14175 TBP; Mammalia. XX DR TRANSPATH: MO000046600. XX RN [1]; RE0009292. RX PUBMED: 8006019. RA Ge H., Roeder R. G. RT The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein RL J. Biol. Chem. 269:17136-17140 (1994). RN [2]; RE0024867. RX PUBMED: 11748232. RA Stros M., Ozaki T., Bacikova A., Kageyama H., Nakagawara A. RT HMGB1 and HMGB2 cell-specifically down-regulate the p53- and p73-dependent sequence-specific transactivation from the human Bax gene promoter. RL J. Biol. Chem. 277:7157-7164 (2002). RN [3]; RE0030139. RX PUBMED: 12456506. RA Fiuza C., Bustin M., Talwar S., Tropea M., Gerstenberger E., Shelhamer J. H., Suffredini A. F. RT Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells. RL Blood 101:2652-60 (2003). RN [4]; RE0030590. RX PUBMED: 12517784. RA Krynetski E. Y., Krynetskaia N. F., Bianchi M. E., Evans W. E. RT A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nucleoside analogues. RL Cancer Res. 63:100-6 (2003). RN [5]; RE0032612. RX PUBMED: 14660645. RA Park J. S., Svetkauskaite D., He Q., Kim J. Y., Strassheim D., Ishizaka A., Abraham E. RT Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. RL J. Biol. Chem. 279:7370-7 (2004). RN [6]; RE0034191. RX PUBMED: 15143181. RA Sorci G., Riuzzi F., Arcuri C., Giambanco I., Donato R. RT Amphoterin stimulates myogenesis and counteracts the antimyogenic factors basic fibroblast growth factor and S100B via RAGE binding. RL Mol. Cell. Biol. 24:4880-94 (2004). RN [7]; RE0040748. RX PUBMED: 10666467. RA Mo X., Bailin T., Noggle S., Sadofsky M. J. RT A highly ordered structure in V(D)J recombination cleavage complexes is facilitated by HMG1 RL Nucleic Acids Res. 28:1228-36 (2000). RN [8]; RE0041234. RX PUBMED: 14739282. RA Melvin V. S., Harrell C., Adelman J. S., Kraus W. L., Churchill M., Edwards D. P. RT The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB RL J. Biol. Chem. 279:14763-71 (2004). RN [9]; RE0044260. RX PUBMED: 9671457. RA Boonyaratanakornkit V., Melvin V., Prendergast P., Altmann M., Ronfani L., Bianchi M. E., Taraseviciene L., Nordeen S. K., Allegretto E. A., Edwards D. P. RT High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells RL Mol. Cell. Biol. 18:4471-87 (1998). RN [10]; RE0046445. RX PUBMED: 12665595. RA Poser I., Golob M., Buettner R., Bosserhoff A. K. RT Upregulation of HMG1 leads to melanoma inhibitory activity expression in malignant melanoma cells and contributes to their malignancy phenotype RL Mol. Cell. Biol. 23:2991-8 (2003). RN [11]; RE0046628. RX PUBMED: 15331624. RA Chen G., Li J., Ochani M., Rendon-Mitchell B., Qiang X., Susarla S., Ulloa L., Yang H., Fan S., Goyert S. M., Wang P., Tracey K. J., Sama A. E., Wang H. RT Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms RL J. Leukoc. Biol. 76:994-1001 (2004). RN [12]; RE0051888. RX PUBMED: 17268551. RA Orlova V. V., Choi E. Y., Xie C., Chavakis E., Bierhaus A., Ihanus E., Ballantyne C. M., Gahmberg C. G., Bianchi M. E., Nawroth P. P., Chavakis T. RT A novel pathway of HMGB1-mediated inflammatory cell recruitment that requires Mac-1-integrin. RL EMBO J. 26:1129-1139 (2007). XX //