AC T17532
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ID T17532
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DT 10.03.2005 (created); nvo.
DT 08.04.2014 (updated); prb.
CO Copyright (C), QIAGEN.
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FA Bcl-3
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SY B-cell leukemia/lymphoma 3; BCL3.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T10346 c-Fos; Mammalia.
IN T09446 c-Jun; Mammalia.
IN T11261 c-Rel; Mammalia.
IN T15118 CBP; Mammalia.
IN T05222 CtBP1; human, Homo sapiens.
IN T14760 ERR1; Mammalia.
IN T34270 LSD1; human, Homo sapiens.
IN T17520 NF-kappaB1; Mammalia.
IN T00394 NF-kappaB2-p52; human, Homo sapiens.
IN T09956 PPARalpha; Mammalia.
IN T21552 SRC-1; Mammalia.
IN T28757 TBLR1; human, Homo sapiens.
IN T28776 TBLR1; human, Homo sapiens.
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BS R30628.
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DR TRANSPATH: MO000047807.
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RN [1]; RE0004533.
RX PUBMED: 8453667.
RA Bours V., Franzoso G., Azarenko V., Park S., Kanno T., Brown K., Siebenlist U.
RT The oncoprotein Bcl-3 directly transactivates through kappaB motifs via association with DNA-binding p50B homodimers
RL Cell 72:729-739 (1993).
RN [2]; RE0027787.
RX PUBMED: 10497212.
RA Na S. Y., Choi J. E., Kim H. J., Jhun B. H., Lee Y. C., Lee J. W.
RT Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.
RL J. Biol. Chem. 274:28491-6 (1999).
RN [3]; RE0028144.
RX PUBMED: 10362352.
RA Dechend R., Hirano F., Lehmann K., Heissmeyer V., Ansieau S., Wulczyn F. G., Scheidereit C., Leutz A.
RT The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators.
RL Oncogene 18:3316-23 (1999).
RN [4]; RE0030177.
RX PUBMED: 12730195.
RA Watanabe N., Wachi S., Fujita T.
RT Identification and characterization of BCL-3-binding protein: implications for transcription and DNA repair or recombination.
RL J. Biol. Chem. 278:26102-10 (2003).
RN [5]; RE0032451.
RX PUBMED: 9885253.
RA Pabla R., Weyrich A. S., Dixon D. A., Bray P. F., McIntyre T. M., Prescott S. M., Zimmerman G. A.
RT Integrin-dependent control of translation: engagement of integrin alphaIIbbeta3 regulates synthesis of proteins in activated human platelets.
RL J. Cell Biol. 144:175-84 (1999).
RN [6]; RE0070618.
RX PUBMED: 20547759.
RA Keutgens A., Shostak K., Close P., Zhang X., Hennuy B., Aussems M., Chapelle J. P., Viatour P., Gothot A., Fillet M., Chariot A.
RT The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.
RL Mol. Cell. Biol. 30:4006-4021 (2010).
RN [7]; RE0072505.
RX PUBMED: 19433446.
RA Morel C., Carlson S. M., White F. M., Davis R. J.
RT Mcl-1 integrates the opposing actions of signaling pathways that mediate survival and apoptosis.
RL Mol. Cell. Biol. 29:3845-3852 (2009).
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