AC T34270
XX
ID T34270
XX
DT 11.08.2006 (created); rad.
DT 05.11.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA LSD1
XX
SY amine oxidase (flavin containing) domain 2; AOF2; BHC110; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; KIAA0601; LSD1; Lysine-specific histone demethylase 1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G033410 KDM1A; HGNC: KDM1A.
XX
IN T05452 BAF155; human, Homo sapiens.
IN T21924 BCL-11A; human, Homo sapiens.
IN T17532 Bcl-3; Mammalia.
IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T00929 Blimp-1; human, Homo sapiens.
IN T17923 Blimp-1; Mammalia.
IN T00207 E47; human, Homo sapiens.
IN T04106 HDAC1; human, Homo sapiens.
IN T08343 HDAC1; human, Homo sapiens.
IN T04109 hdac2-isoform1; human, Homo sapiens.
IN T10759 MTA-1; human, Homo sapiens.
IN T33892 MTA-1; Mammalia.
IN T22425 RCOR1; human, Homo sapiens.
IN T15704 SNA; Mammalia.
IN T01493 STAT3; human, Homo sapiens.
XX
DR TRANSPATH: MO000084915.
DR UniProtKB: O60341; LSD1_HUMAN.
XX
RN [1]; RE0040744.
RX PUBMED: 11171972.
RA You A., Tong J. K., Grozinger C. M., Schreiber S. L.
RT CoREST is an integral component of the CoREST- human histone deacetylase complex
RL Proc. Natl. Acad. Sci. USA 98:1454-8 (2001).
RN [2]; RE0047257.
RX PUBMED: 12032298.
RA Hakimi M. A., Bochar D. A., Chenoweth J., Lane W. S., Mandel G., Shiekhattar R.
RT A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes
RL Proc. Natl. Acad. Sci. USA 99:7420-5 (2002).
RN [3]; RE0048562.
RX PUBMED: 16603237.
RA Yamane K., Toumazou C., Tsukada Y., Erdjument-Bromage H., Tempst P., Wong J., Zhang Y.
RT JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.
RL Cell 125:483-495 (2006).
RN [4]; RE0055166.
RX PUBMED: 15620353.
RA Shi Y., Lan F., Matson C., Mulligan P., Whetstine J. R., Cole P. A., Casero R. A., Shi Y.
RT Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.
RL Cell 119:941-953 (2004).
RN [5]; RE0063261.
RX PUBMED: 16169070.
RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E.
RT A human protein-protein interaction network: a resource for annotating the proteome.
RL Cell 122:957-968 (2005).
RN [6]; RE0063432.
RX PUBMED: 16987819.
RA Forneris F., Binda C., Dall'Aglio A., Fraaije M. W., Battaglioli E., Mattevi A.
RT A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1.
RL J. Biol. Chem. 281:35289-35295 (2006).
RN [7]; RE0070618.
RX PUBMED: 20547759.
RA Keutgens A., Shostak K., Close P., Zhang X., Hennuy B., Aussems M., Chapelle J. P., Viatour P., Gothot A., Fillet M., Chariot A.
RT The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.
RL Mol. Cell. Biol. 30:4006-4021 (2010).
XX
//