AC T04106
XX
ID T04106
XX
DT 12.12.2000 (created); rio.
DT 05.02.2015 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA HDAC1
XX
SY HD1; HDAC-1; histone deacetylase 1; RPD3L1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G003819 HDAC1; HGNC: HDAC1.
XX
SF interaction with YY1 T00915 [4];
SF forms a transcriptional corepressor complex with TGIF T04076 and SMAD T04095 T04096 [2] [3];
XX
CP ubiquitous; T47D, MCF-7 [10].
EX blood,basophil granulocyte,Circulatory System & Hematopoietic System,adult; medium; Northern blot; mRNA (poly-A); [4].
EX blood,eosinophil granulocyte,Circulatory System & Hematopoietic System,adult; medium; Northern blot; mRNA (poly-A); [4].
EX blood,lymphocyte,Circulatory System & Hematopoietic System,adult; medium; Northern blot; mRNA (poly-A); [4].
EX blood,monocyte,Circulatory System & Hematopoietic System,adult; medium; Northern blot; mRNA (poly-A); [4].
EX blood,neutrophil granulocyte,Circulatory System & Hematopoietic System,adult; medium; Northern blot; mRNA (poly-A); [4].
EX brain,,,adult; very low; Northern blot; mRNA (poly-A); [4].
EX heart,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX kidney (right and left),,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX liver,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX lung (right and left),,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX mucosa of colon,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX muscles,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX ovary (right and left),,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX pancreas,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX placenta,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX prostate gland,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX small intestine,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX spleen,,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX testis (right and left),,,adult; medium; Northern blot; mRNA (poly-A); [4].
EX thymus,,,adult; medium; Northern blot; mRNA (poly-A); [4].
XX
FF Binds to the PS2 G000373 promoter both in presence and absence of E2 [46];
FF transcriptional repressor [4];
XX
IN T19483 Apak; human, Homo sapiens.
IN T08487 AR-isoform1; human, Homo sapiens.
IN T00040 AR; human, Homo sapiens.
IN T05452 BAF155; human, Homo sapiens.
IN T05453 BAF60A; human, Homo sapiens.
IN T18773 BCAA-isoform1; human, Homo sapiens.
IN T21924 BCL-11A; human, Homo sapiens.
IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T08887 brca1-isoform1; human, Homo sapiens.
IN T17201 BTEB2; Mammalia.
IN T00137 c-Myb; human, Homo sapiens.
IN T10398 C/EBPdelta; Mammalia.
IN T08519 C2TA-isoform1; human, Homo sapiens.
IN T00100 CDP; human, Homo sapiens.
IN T08505 COUP-TF1; human, Homo sapiens.
IN T02944 Daxx; human, Homo sapiens.
IN T27198 DNA (cytosine-5)-methyltransferase 3B; human, Homo sapiens.
IN T34272 EED; human, Homo sapiens.
IN T00261 ER-alpha; human, Homo sapiens.
IN T25772 ESET-isoform1; mouse, Mus musculus.
IN T05220 Evi-1; human, Homo sapiens.
IN T10210 Evi-1; human, Homo sapiens.
IN T04888 EZH2; human, Homo sapiens.
IN T01462 Fra-1; human, Homo sapiens.
IN T34364 G9A; human, Homo sapiens.
IN T27302 GATAD2A; human, Homo sapiens.
IN T01686 GCN5; human, Homo sapiens.
IN T14242 GKLF-isoform1; human, Homo sapiens.
IN T14243 GKLF; human, Homo sapiens.
IN T00331 gli3; human, Homo sapiens.
IN T03225 Grg-4; clawed frog, Xenopus laevis.
IN T25625 hdac2; human, Homo sapiens.
IN T23099 Hey1; Mammalia.
IN T09068 Hey2; mouse, Mus musculus.
IN T00950 IkappaB-alpha; human, Homo sapiens.
IN T25685 ING1a; human, Homo sapiens.
IN T34270 LSD1; human, Homo sapiens.
IN T00490 MAZ-isoform1; human, Homo sapiens.
IN T16406 MBD2; human, Homo sapiens.
IN T04936 MECP-2; human, Homo sapiens.
IN T09508 Mef-2a; human, Homo sapiens.
IN T09260 MEF-2D; human, Homo sapiens.
IN T18835 Mi2-alpha; human, Homo sapiens.
IN T34374 Mi2-BETA; human, Homo sapiens.
IN T25722 MIER1-isoform1; human, Homo sapiens.
IN T26379 MIER1-isoform5; human, Homo sapiens.
IN T10759 MTA-1; human, Homo sapiens.
IN T05115 MTA1L1; human, Homo sapiens.
IN T25701 MTG8B; human, Homo sapiens.
IN T09420 neurofibromin1; human, Homo sapiens.
IN T00593 NF-kappaB1-p50; human, Homo sapiens.
IN T06148 p/CAF; human, Homo sapiens.
IN T01486 p107; human, Homo sapiens.
IN T21984 p300; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
IN T09500 p53; Mammalia.
IN T06377 PML; human, Homo sapiens.
IN T00722 pRb; human, Homo sapiens.
IN T08171 PSF; human, Homo sapiens.
IN T25623 Rad9a; human, Homo sapiens.
IN T27214 RBBP1; human, Homo sapiens.
IN T22425 RCOR1; human, Homo sapiens.
IN T22433 RCOR1; human, Homo sapiens.
IN T08711 RelA-p65; human, Homo sapiens.
IN T17026 RNF96; human, Homo sapiens.
IN T34689 SAP130-isoform1; human, Homo sapiens.
IN T28755 SAP30; human, Homo sapiens.
IN T10594 SHP; human, Homo sapiens.
IN T14622 sin3a; human, Homo sapiens.
IN T04096 Smad3-isoform1; human, Homo sapiens.
IN T04217 Smad7; human, Homo sapiens.
IN T15704 SNA; Mammalia.
IN T22463 SNF2H; human, Homo sapiens.
IN T00759 Sp1; human, Homo sapiens.
IN T02338 Sp3; human, Homo sapiens.
IN T01494 STAT2; human, Homo sapiens.
IN T08580 STAT3-isoform1; human, Homo sapiens.
IN T11420 Tbx3; human, Homo sapiens.
IN T04076 TGIF; human, Homo sapiens.
IN T31844 topoisomerase-II-alpha; human, Homo sapiens.
IN T02900 UBF; human, Homo sapiens.
IN T26870 uhrf1-isoform2; human, Homo sapiens.
IN T00915 YY1; human, Homo sapiens.
IN T08660 YY1; human, Homo sapiens.
XX
MX M07041 V$HDAC1_Q3.
XX
BS R31240.
BS R31243.
BS R56354.
BS R56347.
BS R56348.
BS R62325.
BS R62052.
BS R62055.
BS R62056.
XX
DR TRANSPATH: MO000023575.
DR SMARTDB: SB000107.
DR UniProtKB: Q13547; HDA1_HUMAN.
XX
RN [1]; RE0014872.
RX PUBMED: 9150135.
RA Zhang Y., Iratni R., Erdjument-Bromage H., Tempst P., Reinberg D.
RT Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex
RL Cell 89:357-364 (1997).
RN [2]; RE0015455.
RX PUBMED: 10601270.
RA Wotton D., Lo R. S., Swaby L. A., Massague J.
RT Multiple modes of repression by the Smad transcriptional corepressor TGIF
RL J. Biol. Chem. 274:37105-37110 (1999).
RN [3]; RE0015456.
RX PUBMED: 10199400.
RA Wotton D., Lo R. S., Lee S., Massague J.
RT A Smad transcriptional corepressor
RL Cell 97:29-39 (1999).
RN [4]; RE0015512.
RX PUBMED: 9346952.
RA Yang W. M., Yao Y. L., Sun J. M., Davie J. R., Seto E.
RT Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family
RL J. Biol. Chem. 272:28001-28007 (1997).
RN [5]; RE0024625.
RX PUBMED: 9620804.
RA Nan X., Ng H.-H., Johnson C. A., Laherty C. D., Turner B. M., Eisenman R. N., Bird A.
RT Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
RL Nature 393:386-389 (1998).
RN [6]; RE0025559.
RX PUBMED: 10846170.
RA Cai R. L., Yan-Neale Y., Cueto M. A., Xu H., Cohen D.
RT HDAC1, a histone deacetylase, forms a complex with Hus1 and Rad9, two G2/M checkpoint Rad proteins.
RL J. Biol. Chem. 275:27909-16 (2000).
RN [7]; RE0027552.
RX PUBMED: 10640275.
RA Huang E. Y., Zhang J., Miska E. A., Guenther M. G., Kouzarides T., Lazar M. A.
RT Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway.
RL Genes Dev. 14:45-54 (2000).
RN [8]; RE0028247.
RX PUBMED: 11430826.
RA Khan M. M., Nomura T., Kim H., Kaul S. C., Wadhwa R., Shinagawa T., Ichikawa-Iwata E., Zhong S., Pandolfi P. P., Ishii S.
RT Role of PML and PML-RARalpha in Mad-mediated transcriptional repression.
RL Mol. Cell 7:1233-43 (2001).
RN [9]; RE0028372.
RX PUBMED: 11486036.
RA Yao Y. L., Yang W. M., Seto E.
RT Regulation of transcription factor YY1 by acetylation and deacetylation.
RL Mol. Cell. Biol. 21:5979-91 (2001).
RN [10]; RE0029152.
RX PUBMED: 11896613.
RA Singh J., Murata K., Itahana Y., Desprez P. Y.
RT Constitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complex.
RL Oncogene 21:1812-22 (2002).
RN [11]; RE0029628.
RX PUBMED: 11994312.
RA Gaughan L., Logan I. R., Cook S., Neal D. E., Robson C. N.
RT Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor.
RL J. Biol. Chem. 277:25904-13 (2002).
RN [12]; RE0029643.
RX PUBMED: 12015309.
RA Vieyra D., Loewith R., Scott M., Bonnefin P., Boisvert F. M., Cheema P., Pastyryeva S., Meijer M., Johnston R. N., Bazett-Jones D. P., McMahon S., Cole M. D., Young D., Riabowol K.
RT Human ING1 proteins differentially regulate histone acetylation.
RL J. Biol. Chem. 277:29832-9 (2002).
RN [13]; RE0029969.
RX PUBMED: 12724404.
RA Fleischer T. C., Yun U. J., Ayer D. E.
RT Identification and Characterization of Three New Components of the mSin3A Corepressor Complex.
RL Mol. Cell. Biol. 23:3456-67 (2003).
RN [14]; RE0031419.
RX PUBMED: 12972430.
RA Viatour P., Legrand-Poels S., van Lint C., Warnier M., Merville M. P., Gielen J., Piette J., Bours V., Chariot A.
RT Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3.
RL J. Biol. Chem. 278:46541-8 (2003).
RN [15]; RE0032276.
RX PUBMED: 14612411.
RA Kim D. W., Lassar A. B.
RT Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2.
RL Mol. Cell. Biol. 23:8704-17 (2003).
RN [16]; RE0033178.
RX PUBMED: 14645718.
RA Nusinzon I., Horvath C. M.
RT Interferon-stimulated transcription and innate antiviral immunity require deacetylase activity and histone deacetylase 1.
RL Proc. Natl. Acad. Sci. USA 100:14742-7 (2003).
RN [17]; RE0037668.
RX PUBMED: 15120635.
RA Geiman T. M., Sankpal U. T., Robertson A. K., Zhao Y., Zhao Y., Robertson K. D.
RT DNMT3B interacts with hSNF2H chromatin remodeling enzyme, HDACs 1 and 2, and components of the histone methylation system
RL Biochem. Biophys. Res. Commun. 318:544-55 (2004).
RN [18]; RE0037672.
RX PUBMED: 15148359.
RA Geiman T. M., Sankpal U. T., Robertson A. K., Chen Y., Mazumdar M., Heale J. T., Schmiesing J. A., Kim W., Yokomori K., Zhao Y., Robertson K. D.
RT Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery
RL Nucleic Acids Res. 32:2716-29 (2004).
RN [19]; RE0038054.
RX PUBMED: 11777905.
RA Johnson C. A., White D. A., Lavender J. S., O Neill L. P., Turner B. M.
RT Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70
RL J. Biol. Chem. 277:9590-7 (2002).
RN [20]; RE0038073.
RX PUBMED: 11533236.
RA Amann J. M., Nip J., Strom D. K., Lutterbach B., Harada H., Lenny N., Downing J. R., Meyers S., Hiebert S. W.
RT ETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domain
RL Mol. Cell. Biol. 21:6470-83 (2001).
RN [21]; RE0038125.
RX PUBMED: 11532945.
RA Yang W. M., Yao Y. L., Seto E.
RT The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1
RL EMBO J. 20:4814-25 (2001).
RN [22]; RE0038632.
RX PUBMED: 11585818.
RA Satou A., Taira T., Iguchi-Ariga S. M., Ariga H.
RT A novel transrepression pathway of c-Myc. Recruitment of a transcriptional corepressor complex to c-Myc by MM-1, a c-Myc-binding protein
RL J. Biol. Chem. 276:46562-7 (2001).
RN [23]; RE0040744.
RX PUBMED: 11171972.
RA You A., Tong J. K., Grozinger C. M., Schreiber S. L.
RT CoREST is an integral component of the CoREST- human histone deacetylase complex
RL Proc. Natl. Acad. Sci. USA 98:1454-8 (2001).
RN [24]; RE0041634.
RX PUBMED: 11571228.
RA Wotton D., Knoepfler P. S., Laherty C. D., Eisenman R. N., Massague J.
RT The Smad transcriptional corepressor TGIF recruits mSin3
RL Cell Growth Differ. 12:457-63 (2001).
RN [25]; RE0041859.
RX PUBMED: 11306568.
RA Liberati N. T., Moniwa M., Borton A. J., Davie J. R., Wang X. F.
RT An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*
RL J. Biol. Chem. 276:22595-603 (2001).
RN [26]; RE0044860.
RX PUBMED: 10581039.
RA van der Vlag J., Otte A. P.
RT Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation
RL Nat. Genet. 23:474-8 (1999).
RN [27]; RE0047249.
RX PUBMED: 12398767.
RA Yang L., Mei Q., Zielinska-Kwiatkowska A., Matsui Y., Blackburn M. L., Benedetti D., Krumm A. A., Taborsky G. J. Jr, Chansky H. A.
RT An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B
RL Biochem. J. 369:651-7 (2003).
RN [28]; RE0047257.
RX PUBMED: 12032298.
RA Hakimi M. A., Bochar D. A., Chenoweth J., Lane W. S., Mandel G., Shiekhattar R.
RT A core-BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes
RL Proc. Natl. Acad. Sci. USA 99:7420-5 (2002).
RN [29]; RE0047295.
RX PUBMED: 11062478.
RA Tsai S. C., Valkov N., Yang W. M., Gump J., Sullivan D., Seto E.
RT Histone deacetylase interacts directly with DNA topoisomerase II
RL Nat. Genet. 26:349-53 (2000).
RN [30]; RE0047460.
RX PUBMED: 15713663.
RA Fu M., Rao M., Bouras T., Wang C., Wu K., Zhang X., Li Z., Yao T. P., Pestell R. G.
RT Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment.
RL J. Biol. Chem. 280:16934-16941 (2005).
RN [31]; RE0047547.
RX PUBMED: 11146623.
RA Mazumdar A., Wang R. A., Mishra S. K., Adam L., Bagheri-Yarmand R., Mandal M., Vadlamudi R. K., Kumar R.
RT Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor.
RL Nat. Cell Biol. 3:30-37 (2001).
RN [32]; RE0047553.
RX PUBMED: 11929879.
RA Milutinovic S., Zhuang Q., Szyf M.
RT Proliferating cell nuclear antigen associates with histone deacetylase activity, integrating DNA replication and chromatin modification.
RL J. Biol. Chem. 277:20974-20978 (2002).
RN [33]; RE0047766.
RX PUBMED: 11788710.
RA Vaute O., Nicolas E., Vandel L., Trouche D.
RT Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.
RL Nucleic Acids Res. 30:475-481 (2002).
RN [34]; RE0047781.
RX PUBMED: 12697811.
RA Zika E., Greer S. F., Zhu X. S., Ting J. P.
RT Histone deacetylase 1/mSin3A disrupts gamma interferon-induced CIITA function and major histocompatibility complex class II enhanceosome formation.
RL Mol. Cell. Biol. 23:3091-3102 (2003).
RN [35]; RE0047839.
RX PUBMED: 11136718.
RA Johnson C. A., Padget K., Austin C. A., Turner B. M.
RT Deacetylase activity associates with topoisomerase II and is necessary for etoposide-induced apoptosis.
RL J. Biol. Chem. 276:4539-4542 (2001).
RN [36]; RE0047858.
RX PUBMED: 12198164.
RA Vietor I., Vadivelu S. K., Wick N., Hoffman R., Cotten M., Seiser C., Fialka I., Wunderlich W., Haase A., Korinkova G., Brosch G., Huber L. A.
RT TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells.
RL EMBO J. 21:4621-4631 (2002).
RN [37]; RE0047878.
RX PUBMED: 12045192.
RA Anderson L. A., Perkins N. D.
RT The large subunit of replication factor C interacts with the histone deacetylase, HDAC1.
RL J. Biol. Chem. 277:29550-29554 (2002).
RN [38]; RE0047881.
RX PUBMED: 15451426.
RA Nikolaev A. Y., Papanikolaou N. A., Li M., Qin J., Gu W.
RT Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex.
RL Biochem. Biophys. Res. Commun. 323:1216-1222 (2004).
RN [39]; RE0047901.
RX PUBMED: 15640443.
RA Gaughan L., Logan I. R., Neal D. E., Robson C. N.
RT Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation.
RL Nucleic Acids Res. 33:13-26 (2005).
RN [40]; RE0047909.
RX PUBMED: 12482978.
RA Ding Z., Gillespie L. L., Paterno G. D.
RT Human MI-ER1 alpha and beta function as transcriptional repressors by recruitment of histone deacetylase 1 to their conserved ELM2 domain.
RL Mol. Cell. Biol. 23:250-258 (2003).
RN [41]; RE0047936.
RX PUBMED: 10669754.
RA Li H., Leo C., Zhu J., Wu X., O'Neil J., Park E. J., Chen J. D.
RT Sequestration and inhibition of Daxx-mediated transcriptional repression by PML.
RL Mol. Cell. Biol. 20:1784-1796 (2000).
RN [42]; RE0048072.
RX PUBMED: 12529406.
RA Yamagoe S., Kanno T., Kanno Y., Sasaki S., Siegel R. M., Lenardo M. J., Humphrey G., Wang Y., Nakatani Y., Howard B. H., Ozato K.
RT Interaction of histone acetylases and deacetylases in vivo.
RL Mol. Cell. Biol. 23:1025-1033 (2003).
RN [43]; RE0048154.
RX PUBMED: 10984530.
RA Downes M., Ordentlich P., Kao H. Y., Alvarez J. G., Evans R. M.
RT Identification of a nuclear domain with deacetylase activity.
RL Proc. Natl. Acad. Sci. USA 97:10330-10335 (2000).
RN [44]; RE0048205.
RX PUBMED: 10220405.
RA Yarden R. I., Brody L. C.
RT BRCA1 interacts with components of the histone deacetylase complex.
RL Proc. Natl. Acad. Sci. USA 96:4983-4988 (1999).
RN [45]; RE0048494.
RX PUBMED: 9819404.
RA Lutterbach B., Westendorf J. J., Linggi B., Patten A., Moniwa M., Davie J. R., Huynh K. D., Bardwell V. J., Lavinsky R. M., Rosenfeld M. G., Glass C., Seto E., Hiebert S. W.
RT ETO, a target of t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors.
RL Mol. Cell. Biol. 18:7176-7184 (1998).
RN [46]; RE0048550.
RX PUBMED: 15541729.
RA Sun J. M., Spencer V. A., Li L., Yu Chen H., Yu J., Davie J. R.
RT Estrogen regulation of trefoil factor 1 expression by estrogen receptor alpha and Sp proteins.
RL Exp. Cell Res. 302:96-107 (2005).
RN [47]; RE0048851.
RX PUBMED: 11486045.
RA Iso T., Sartorelli V., Poizat C., Iezzi S., Wu H. Y., Chung G., Kedes L., Hamamori Y.
RT HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling.
RL Mol. Cell. Biol. 21:6080-6089 (2001).
RN [48]; RE0048880.
RX PUBMED: 12529400.
RA Ecsedy J. A., Michaelson J. S., Leder P.
RT Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.
RL Mol. Cell. Biol. 23:950-960 (2003).
RN [49]; RE0048921.
RX PUBMED: 15961388.
RA Zeng L., Hu Y., Li B.
RT Identification of TopBP1 as a c-Abl-interacting protein and a repressor for c-Abl expression.
RL J. Biol. Chem. 280:29374-29380 (2005).
RN [50]; RE0051082.
RX PUBMED: 17895379.
RA Sanyal S., Bavner A., Haroniti A., Nilsson L. M., Lundasen T., Rehnmark S., Witt M. R., Einarsson C., Talianidis I., Gustafsson J. A., Treuter E.
RT Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.
RL Proc. Natl. Acad. Sci. USA 104:15665-15670 (2007).
RN [51]; RE0051864.
RX PUBMED: 17000776.
RA Liu Y., Smith P. W., Jones D. R.
RT Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis.
RL Mol. Cell. Biol. 26:8683-8696 (2006).
RN [52]; RE0052156.
RX PUBMED: 12176973.
RA Sun J. M., Chen H. Y., Moniwa M., Litchfield D. W., Seto E., Davie J. R.
RT The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2.
RL J. Biol. Chem. 277:35783-35786 (2002).
RN [53]; RE0052206.
RX PUBMED: 12082111.
RA Tsai S. C., Seto E.
RT Regulation of histone deacetylase 2 by protein kinase CK2.
RL J. Biol. Chem. 277:31826-31833 (2002).
RN [54]; RE0052309.
RX PUBMED: 10490602.
RA Lai A., Lee J. M., Yang W. M., DeCaprio J. A., Kaelin WG J. r., Seto E., Branton P. E.
RT RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteins.
RL Mol. Cell. Biol. 19:6632-6641 (1999).
RN [55]; RE0052392.
RX PUBMED: 15298701.
RA Wilson B. J., Bates G. J., Nicol S. M., Gregory D. J., Perkins N. D., Fuller-Pace F. V.
RT The p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific manner.
RL BMC Mol. Biol. 5:11 (2004).
RN [56]; RE0052535.
RX PUBMED: 10471499.
RA Ng H. H., Zhang Y., Hendrich B., Johnson C. A., Turner B. M., Erdjument-Bromage H., Tempst P., Reinberg D., Bird A.
RT MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.
RL Nat. Genet. 23:58-61 (1999).
RN [57]; RE0052627.
RX PUBMED: 12634383.
RA Knight J. S., Lan K., Subramanian C., Robertson E. S.
RT Epstein-Barr virus nuclear antigen 3C recruits histone deacetylase activity and associates with the corepressors mSin3A and NCoR in human B-cell lines.
RL J. Virol. 77:4261-4272 (2003).
RN [58]; RE0052675.
RX PUBMED: 11259576.
RA Wu W. S., Vallian S., Seto E., Yang W. M., Edmondson D., Roth S., Chang K. S.
RT The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases.
RL Mol. Cell. Biol. 21:2259-2268 (2001).
RN [59]; RE0053042.
RX PUBMED: 10888886.
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