TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T08711 XX ID T08711 XX DT 17.03.2006 (created); sou. DT 26.05.2016 (updated); vis. CO Copyright (C), QIAGEN. XX FA RelA-p65 XX SY NF-kappaB (p65); NFKB3; Nuclear Factor kappa B p65; Rel-A; RelA; Transcription factor p65. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004622 RELA; HGNC: RELA. XX CL C0020; Rel; XX CP K562 cells treated with t-BHQ (tert-butylhydroquinone) and PMA(Phorbol 12-myristate 13-acetate) [22]; HUVEC [43]. XX FF TNF-alpha induction is abrogated by DOX (doxorubicin) [41]; XX IN T04074 brca1; human, Homo sapiens. IN T30638 BRD4; human, Homo sapiens. IN T15118 CBP; Mammalia. IN T18378 CBP; human, Homo sapiens. IN T00100 CDP; human, Homo sapiens. IN T18364 Clock; Mammalia. IN T06040 CtBP2; human, Homo sapiens. IN T05839 DEC2; human, Homo sapiens. IN T06570 Dnmt1; human, Homo sapiens. IN T22508 dpf2-isoform1; human, Homo sapiens. IN T33762 DRIP205; human, Homo sapiens. IN T01542 E2F-1; human, Homo sapiens. IN T09570 E2F-1; Mammalia. IN T17403 E2F-2; Mammalia. IN T17404 E2F-3; Mammalia. IN T09462 Egr-1; human, Homo sapiens. IN T00261 ER-alpha; human, Homo sapiens. IN T05220 Evi-1; human, Homo sapiens. IN T04956 FKLF; human, Homo sapiens. IN T06587 Gfi1; human, Homo sapiens. IN T27186 GILZ-isoform1; human, Homo sapiens. IN T19182 GLEA2; human, Homo sapiens. IN T04106 HDAC1; human, Homo sapiens. IN T28193 HES6; Mammalia. IN T01610 HIF-1alpha; human, Homo sapiens. IN T14419 Id1; human, Homo sapiens. IN T00950 IkappaB-alpha; human, Homo sapiens. IN T08767 IkappaB-alpha; human, Homo sapiens. IN T18455 IkappaB-alpha; Mammalia. IN T00414 IkappaB-beta; human, Homo sapiens. IN T22412 IkappaB-epsilon; human, Homo sapiens. IN T17890 ing4-isoform1; human, Homo sapiens. IN T17025 ing4; human, Homo sapiens. IN T00593 NF-kappaB1-p50; human, Homo sapiens. IN T01925 NF-kappaB1; human, Homo sapiens. IN T15707 NF-kappaB2-p52; human, Homo sapiens. IN T21984 p300; human, Homo sapiens. IN T14055 PARP; human, Homo sapiens. IN T02726 PPARalpha; human, Homo sapiens. IN T16551 RBTN2; human, Homo sapiens. IN T17026 RNF96; human, Homo sapiens. IN T29717 SIRT1; human, Homo sapiens. IN T30703 SIRT1; Mammalia. IN T08326 Sp1; Mammalia. IN T22422 SRC3-xbb2; human, Homo sapiens. IN T00857 TTF-1; human, Homo sapiens. IN T00878 USF2; human, Homo sapiens. IN T08660 YY1; human, Homo sapiens. IN T19456 ZNF277; human, Homo sapiens. XX MX M00052 V$NFKAPPAB65_01. MX M00054 V$NFKAPPAB_01. MX M00774 V$NFKB_Q6_01. MX M04706 V$RELA_02. MX M04811 V$RELA_03. MX M04814 V$RELA_04. MX M04849 V$RELA_05. MX M03563 V$RELA_Q6. XX BS R20825. BS R02921. BS R26202. BS R19592. BS R61153. BS R56830. BS R56831. BS R56846. BS R56841. BS R56833. BS R56844. BS R41748. BS R57626. BS R57628. BS R69104. BS R69105. BS R38574. BS R39203. BS R27918. BS R30510. BS R40311. BS R56879. BS R61726. BS R72669. BS R72670. BS R72671. BS R72672. BS R56363. BS R56364. BS R66891. BS R66893. BS R66894. BS R37334. BS R57003. BS R57006. BS R56894. BS R25550. BS R25553. BS R21071. BS R21072. BS R32966. BS R39660. BS R62607. BS R25011. BS R25318. BS R59335. BS R65616. BS R62771. BS R60747. BS R32905. BS R39495. BS R69819. BS R59482. BS R67066. BS R33333. BS R33335. BS R37622. BS R37626. BS R37631. BS R60309. BS R27591. BS R35327. BS R60171. BS R60172. BS R33602. BS R32146. BS R32147. BS R32148. BS R03340. BS R32145. BS R23158. BS R23160. BS R23162. BS R73825. BS R64997. BS R70893. BS R70894. BS R70895. BS R70896. BS R70897. BS R29232. BS R29238. BS R29912. BS R56884. BS R19559. BS R19561. BS R59980. BS R69855. BS R68147. BS R68149. BS R68151. BS R66705. BS R56624. BS R56626. BS R27973. BS R35205. BS R22943. BS R27700. BS R20329. BS R56892. BS R22435. BS R68579. BS R28359. BS R34970. BS R73757. BS R25932. BS R65270. BS R56860. BS R19572. BS R35058. BS R34717. BS R24757. BS R66737. BS R27927. BS R30655. BS R30369. BS R30650. BS R29952. BS R28669. BS R35342. BS R66266. BS R01634. BS R03553. BS R25017. BS R30979. BS R35449. BS R02909. BS R30143. BS R66728. BS R29805. BS R34823. BS R24123. BS R25474. BS R25475. BS R61845. BS R39330. BS R60527. BS R60528. BS R60529. BS R31357. BS R66346. BS R73718. BS R39356. BS R39357. BS R64354. BS R29732. BS R37557. BS R39916. BS R35961. BS R73819. BS R37554. BS R29088. BS R31641. BS R31643. BS R64535. BS R73743. BS R69147. BS R62619. BS R56352. BS R56353. BS R64532. BS R63990. BS R56345. BS R56346. BS R19783. BS R61229. BS R65534. BS R30683. BS R40081. BS R35143. BS R25405. BS R37736. BS R56896. BS R28216. BS R66747. BS R68249. BS R68253. BS R27455. BS R27108. BS R31072. BS R64619. BS R29578. BS R24815. BS R32640. BS R19739. BS R19741. BS R19742. BS R27453. BS R35969. BS R40952. BS R40702. BS R40734. BS R40743. BS R40744. BS R11382. BS R37884. BS R37885. BS R32364. BS R41595. BS R22506. BS R64893. BS R65350. BS R65351. BS R62694. BS R62696. BS R35448. BS R66698. BS R66699. BS R66701. BS R37632. BS R37636. BS R37640. BS R39068. BS R65966. BS R57300. BS R57301. BS R26906. BS R27891. BS R34802. BS R30908. BS R30966. BS R34834. BS R67504. BS R67507. BS R01349. BS R32736. BS R57945. BS R57950. BS R69492. BS R34710. BS R37951. BS R56876. BS R56885. BS R69261. BS R69262. BS R73357. BS R38700. BS R42205. BS R71694. BS R71695. BS R71697. BS R62490. BS R63242. BS R42030. BS R29217. BS R29223. BS R56877. BS R56878. BS R26907. BS R29852. BS R62539. BS R62543. BS R56886. BS R30054. BS R66742. BS R66749. BS R24873. BS R59995. BS R61067. BS R61068. BS R73153. BS R37715. BS R64783. BS R71773. BS R72271. BS R72272. BS R72273. BS R39956. BS R60584. BS R56865. BS R56872. BS R56881. BS R26754. BS R35547. BS R65334. BS R67205. BS R67207. BS R57770. BS R56665. BS R22751. BS R22752. BS R32472. BS R01058. BS R55836. BS R30716. XX DR TRANSPATH: MO000079319. DR TRANSCOMPEL: C00577. DR UniProtKB: Q04206; XX RN [1]; RE0013471. RX PUBMED: 9135156. RA Whiteside S. T., Epinat J. C., Rice N. R., Israel A. RT I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity. RL EMBO J. 16:1413-1426 (1997). RN [2]; RE0021997. RX PUBMED: 9751059. RA Cohen L., Henzel W. J., Baeuerle P. A. RT IKAP is a scaffold protein of the IkappaB kinase complex RL Nature 395:292-296 (1998). RN [3]; RE0030415. RX PUBMED: 12842894. RA Sakurai H., Suzuki S., Kawasaki N., Nakano H., Okazaki T., Chino A., Doi T., Saiki I. RT Tumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. RL J. Biol. Chem. 278:36916-23 (2003). RN [4]; RE0031419. RX PUBMED: 12972430. RA Viatour P., Legrand-Poels S., van Lint C., Warnier M., Merville M. P., Gielen J., Piette J., Bours V., Chariot A. RT Cytoplasmic IkappaBalpha increases NF-kappaB-independent transcription through binding to histone deacetylase (HDAC) 1 and HDAC3. RL J. Biol. Chem. 278:46541-8 (2003). RN [5]; RE0032702. RX PUBMED: 12419817. RA Jiang X., Takahashi N., Matsui N., Tetsuka T., Okamoto T. RT The NF-kappa B activation in lymphotoxin beta receptor signaling depends on the phosphorylation of p65 at serine 536. RL J. Biol. Chem. 278:919-26 (2003). RN [6]; RE0033324. RX PUBMED: 14976190. RA Catley M. C., Cambridge L. M., Nasuhara Y., Ito K., Chivers J. E., Beaton A., Holden N. S., Bergmann M. W., Barnes P. J., Newton R. RT Inhibitors of protein kinase C (PKC) prevent activated transcription: role of events downstream of NF-kappaB DNA binding. RL J. Biol. Chem. 279:18457-66 (2004). RN [7]; RE0046041. RX PUBMED: 12040027. RA Islam K. N., Mendelson C. R. RT Potential role of nuclear factor kappaB and reactive oxygen species in cAMP and cytokine regulation of surfactant protein-A gene expression in lung type II cells RL Mol. Endocrinol. 16:1428-40 (2002). RN [8]; RE0046561. RX PUBMED: 11468175. RA Ayroldi E., Migliorati G., Bruscoli S., Marchetti C., Zollo O., Cannarile L., D'Adamio F., Riccardi C. RT Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB RL Blood 98:743-53 (2001). RN [9]; RE0047693. RX PUBMED: 15489227. RA Buss H., Dorrie A., Schmitz M. L., Hoffmann E., Resch K., Kracht M. RT Constitutive and interleukin-1-inducible phosphorylation of p65 NF-{kappa}B at serine 536 is mediated by multiple protein kinases including I{kappa}B kinase (IKK)-{alpha}, IKK{beta}, IKK{epsilon}, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. RL J. Biol. Chem. 279:55633-55643 (2004). RN [10]; RE0048086. RX PUBMED: 11526476. RA Heppner C., Bilimoria K. Y., Agarwal S. K., Kester M., Whitty L. J., Guru S. C., Chandrasekharappa S. C., Collins F. S., Spiegel A. M., Marx S. J., Burns A. L. RT The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. RL Oncogene 20:4917-4925 (2001). RN [11]; RE0048186. RX PUBMED: 15383283. RA Wu R. C., Qin J., Yi P., Wong J., Tsai S. Y., Tsai M. J., O'Malley B. W. RT Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. RL Mol. Cell 15:937-949 (2004). RN [12]; RE0048413. RX PUBMED: 16728495. RA Zeold A., Doleschall M., Haffner M. C., Capelo L. P., Menyhert J., Liposits Z., da Silva W. S., Bianco A. C., Kacskovics I., Fekete C., Gereben B. RT Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene. RL Endocrinology 147:4419-4429 (2006). RN [13]; RE0048827. RX PUBMED: 15913553. RA Becker T. M., Rizos H., de la Pena A., Leclercq I. A., Woodruff S., Kefford R. F., Mann G. J. RT Impaired inhibition of NF-kappaB activity by melanoma-associated p16INK4a mutations. RL Biochem. Biophys. Res. Commun. 332:873-879 (2005). RN [14]; RE0049054. RX PUBMED: 10671503. RA Chapman N. R., Perkins N. D. RT Inhibition of the RelA(p65) NF-kappaB subunit by Egr-1. RL J. Biol. Chem. 275:4719-4725 (2000). RN [15]; RE0049372. RX PUBMED: 11336543. RA Zhu N., Ware C. F., Lai M. M. RT Hepatitis C virus core protein enhances FADD-mediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor. RL Virology 283:178-187 (2001). RN [16]; RE0049828. RX PUBMED: 16204234. RA Hassa P. O., Haenni S. S., Buerki C., Meier N. I., Lane W. S., Owen H., Gersbach M., Imhof R., Hottiger M. O. RT Acetylation of poly(ADP-ribose) polymerase-1 by p300/CREB-binding protein regulates coactivation of NF-kappaB-dependent transcription. RL J. Biol. Chem. 280:40450-40464 (2005). RN [17]; RE0049976. RX PUBMED: 17434128. RA Huang W. C., Ju T. K., Hung M. C., Chen C. C. RT Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. RL Mol. Cell 26:75-87 (2007). RN [18]; RE0050028. RX PUBMED: 14690596. RA Ryo A., Suizu F., Yoshida Y., Perrem K., Liou Y. C., Wulf G., Rottapel R., Yamaoka S., Lu K. P. RT Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. RL Mol. Cell 12:1413-1426 (2003). RN [19]; RE0050192. RX PUBMED: 15592525. RA Jun J. I., Chung C. W., Lee H. J., Pyo J. O., Lee K. N., Kim N. S., Kim Y. S., Yoo H. S., Lee T. H., Kim E., Jung Y. K. RT Role of FLASH in caspase-8-mediated activation of NF-kappaB: dominant-negative function of FLASH mutant in NF-kappaB signaling pathway. RL Oncogene 24:688-696 (2005). RN [20]; RE0050802. RX PUBMED: 12700228. RA Benezra M., Chevallier N., Morrison D. J., MacLachlan T. K., El-Deiry W. S., Licht J. D. RT BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit. RL J. Biol. Chem. 278:26333-26341 (2003). RN [21]; RE0051619. RX PUBMED: 15951441. RA Hu W. H., Pendergast J. S., Mo X. M., Brambilla R., Bracchi-Ricard V., Li F., Walters W. M., Blits B., He L., Schaal S. M., Bethea J. R. RT NIBP, a novel NIK and IKK(beta)-binding protein that enhances NF-(kappa)B activation. RL J. Biol. Chem. 280:29233-29241 (2005). RN [22]; RE0051628. RX PUBMED: 15640523. RA Arinze I. J., Kawai Y. RT Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements. RL J. Biol. Chem. 280:9786-9795 (2005). RN [23]; RE0051641. RX PUBMED: 15208311. RA Hu W. H., Mo X. M., Walters W. M., Brambilla R., Bethea J. R. RT TNAP, a novel repressor of NF-kappaB-inducing kinase, suppresses NF-kappaB activation. RL J. Biol. Chem. 279:35975-35983 (2004). RN [24]; RE0051660. RX PUBMED: 16046471. RA Schwabe R. F., Sakurai H. RT IKKbeta phosphorylates p65 at S468 in transactivaton domain 2. RL FASEB J. 19:1758-1760 (2005). RN [25]; RE0051716. RX PUBMED: 12748188. RA Asamitsu K., Tetsuka T., Kanazawa S., Okamoto T. RT RING finger protein AO7 supports NF-kappaB-mediated transcription by interacting with the transactivation domain of the p65 subunit. RL J. Biol. Chem. 278:26879-26887 (2003). RN [26]; RE0051818. RX PUBMED: 18178962. RA Gao N., Asamitsu K., Hibi Y., Ueno T., Okamoto T. RT AKIP1 augments NF-kappa B-dependent gene expression by promoting the nuclear retention and phosphorylation of p65. RL J. Biol. Chem. 283:7834-7843 (2008). RN [27]; RE0051828. RX PUBMED: 18035048. RA Kwon O., Kim K. A., He L., Jung M., Jeong S. J., Ahn J. S., Kim B. Y. RT Complex formation of p65/RelA with nuclear Akt1 for enhanced transcriptional activation of NF-kappaB. RL Biochem. Biophys. Res. Commun. 365:771-776 (2008). RN [28]; RE0051862. RX PUBMED: 17196614. RA Owen H. R., Elser M., Cheung E., Gersbach M., Kraus W. L., Hottiger M. O. RT MYBBP1a is a novel repressor of NF-kappaB. RL J. Mol. Biol. 366:725-736 (2007). RN [29]; RE0051864. RX PUBMED: 17000776. RA Liu Y., Smith P. W., Jones D. R. RT Breast cancer metastasis suppressor 1 functions as a corepressor by enhancing histone deacetylase 1-mediated deacetylation of RelA/p65 and promoting apoptosis. RL Mol. Cell. Biol. 26:8683-8696 (2006). RN [30]; RE0051899. RX PUBMED: 18056395. RA Lakshmanan U., Porter A. G. RT Caspase-4 interacts with TNF receptor-associated factor 6 and mediates lipopolysaccharide-induced NF-kappaB-dependent production of IL-8 and CC chemokine ligand 4 (macrophage-inflammatory protein-1 ). RL J. Immunol. 179:8480-8490 (2007). RN [31]; RE0051930. RX PUBMED: 17644309. RA Yamaguchi T., Miki Y., Yoshida K. RT Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress. RL Cell. Signal. 19:2088-2097 (2007). RN [32]; RE0051949. RX PUBMED: 16382138. RA Hoberg J. E., Popko A. E., Ramsey C. S., Mayo M. W. RT IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300. RL Mol. Cell. Biol. 26:457-471 (2006). RN [33]; RE0051974. RX PUBMED: 15494311. RA Hoberg J. E., Yeung F., Mayo M. W. RT SMRT derepression by the IkappaB kinase alpha: a prerequisite to NF-kappaB transcription and survival. RL Mol. Cell 16:245-255 (2004). RN [34]; RE0052155. RX PUBMED: 15152190. RA Yeung F., Hoberg J. E., Ramsey C. S., Keller M. D., Jones D. R., Frye R. A., Mayo M. W. RT Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. RL EMBO J. 23:2369-2380 (2004). RN [35]; RE0052363. RX PUBMED: 15625114. RA Lau D., Mollnau H., Eiserich J. P., Freeman B. A., Daiber A., Gehling U. M., Brummer J., Rudolph V., Munzel T., Heitzer T., Meinertz T., Baldus S. RT Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. RL Proc. Natl. Acad. Sci. USA 102:431-436 (2005). RN [36]; RE0052381. RX PUBMED: 17595324. RA Choudhary S., Lu M., Cui R., Brasier A. R. RT Involvement of a novel Rac/RhoA guanosine triphosphatase-nuclear factor-kappaB inducing kinase signaling pathway mediating angiotensin II-induced RelA transactivation. RL Mol. Endocrinol. 21:2203-2217 (2007). RN [37]; RE0053061. RX PUBMED: 17296604. RA Johnson J., Albarani V., Nguyen M., Goldman M., Willems F., Aksoy E. RT Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis. RL J. Biol. Chem. 282:15022-15032 (2007). RN [38]; RE0053154. RX PUBMED: 17991436. RA Hochrainer K., Racchumi G., Anrather J. RT Hypo-phosphorylation leads to nuclear retention of NF-kappaB p65 due to impaired IkappaBalpha gene synthesis. RL FEBS Lett. 581:5493-5499 (2007). RN [39]; RE0053206. RX PUBMED: 17183367. RA Maine G. N., Mao X., Komarck C. M., Burstein E. RT COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. RL EMBO J. 26:436-447 (2007). RN [40]; RE0053386. RX PUBMED: 18383035. RA Gregory D. J., Godbout M., Contreras I., Forget G., Olivier M. RT A novel form of NF-kappaB is induced by Leishmania infection: involvement in macrophage gene expression. RL Eur. J. Immunol. 38:1071-1081 (2008). RN [41]; RE0053436. RX PUBMED: 16483679. RA Cao W., Ma S. L., Tang J., Shi J., Lu Y. RT A combined treatment TNF-alpha/doxorubicin alleviates the resistance of MCF-7/Adr cells to cytotoxic treatment. RL Biochim. Biophys. Acta 1763:182-187 (2006). RN [42]; RE0053439. RX PUBMED: 17468759. RA Tanaka T., Grusby M. J., Kaisho T. RT PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. RL Nat. Immunol. 8:584-591 (2007). RN [43]; RE0053454. RX PUBMED: 17675290. RA Wang J., Mahmud S. A., Bitterman P. B., Huo Y., Slungaard A. RT Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. RL J. Biol. Chem. 282:28408-28418 (2007). RN [44]; RE0053529. RX PUBMED: 10655476. RA Huang T. T., Kudo N., Yoshida M., Miyamoto S. RT A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes. RL Proc. Natl. Acad. Sci. USA 97:1014-1019 (2000). RN [45]; RE0053645. RX PUBMED: 18045535. RA Wan F., Anderson D. E., Barnitz R. A., Snow A., Bidere N., Zheng L., Hegde V., Lam L. T., Staudt L. M., Levens D., Deutsch W. A., Lenardo M. J. RT Ribosomal protein S3: a KH domain subunit in NF-kappaB complexes that mediates selective gene regulation. RL Cell 131:927-939 (2007). RN [46]; RE0053748. RX PUBMED: 12871932. RA Demarchi F., Bertoli C., Sandy P., Schneider C. RT Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability. RL J. Biol. Chem. 278:39583-39590 (2003). RN [47]; RE0053839. RX PUBMED: 16407239. RA Mattioli I., Geng H., Sebald A., Hodel M., Bucher C., Kracht M., Schmitz M. L. RT Inducible phosphorylation of NF-kappa B p65 at serine 468 by T cell costimulation is mediated by IKK epsilon. RL J. Biol. Chem. 281:6175-6183 (2006). RN [48]; RE0053894. RX PUBMED: 17307160. RA Lin C. C., Chiang L. L., Lin C. H., Shih C. H., Liao Y. T., Hsu M. J., Chen B. C. RT Transforming growth factor-beta1 stimulates heme oxygenase-1 expression via the PI3K/Akt and NF-kappaB pathways in human lung epithelial cells. RL Eur. J. Pharmacol. 560:101-109 (2007). RN [49]; RE0053911. RX PUBMED: 18424438. RA Joo J. H., Jetten A. M. RT NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway. RL J. Biol. Chem. 283:16391-16399 (2008). RN [50]; RE0053976. RX PUBMED: 15708970. RA Hauer J., Puschner S., Ramakrishnan P., Simon U., Bongers M., Federle C., Engelmann H. RT TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs. RL Proc. Natl. Acad. Sci. USA 102:2874-2879 (2005). RN [51]; RE0054060. RX PUBMED: 12789342. RA Yamamoto Y., Verma U. N., Prajapati S., Kwak Y. T., Gaynor R. B. RT Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression. RL Nature 423:655-659 (2003). RN [52]; RE0054072. RX PUBMED: 11687592. RA Solan N. J., Miyoshi H., Carmona E. M., Bren G. D., Paya C. V. RT RelB cellular regulation and transcriptional activity are regulated by p100. RL J. Biol. Chem. 277:1405-1418 (2002). RN [53]; RE0054190. RX PUBMED: 12820969. RA Saccani S., Pantano S., Natoli G. RT Modulation of NF-kappaB activity by exchange of dimers. RL Mol. Cell 11:1563-1574 (2003). RN [54]; RE0054529. RX PUBMED: 17785851. RA Liu G., Tsuruta Y., Gao Z., Park Y. J., Abraham E. 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