AC T17026
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ID T17026
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DT 13.02.2006 (created); sbr.
DT 23.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA RNF96
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SY FLJ29029; Hs.433612; KAP-1; KAP1; PPP1R157; RNF96; TF1B; TIF1B; TRIM28; tripartite motif containing 28; tripartite motif-containing 28.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G019861 TRIM28; HGNC: TRIM28.
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IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T00149 COUP-TF1; human, Homo sapiens.
IN T08505 COUP-TF1; human, Homo sapiens.
IN T18011 ESET; human, Homo sapiens.
IN T34364 G9A; human, Homo sapiens.
IN T04106 HDAC1; human, Homo sapiens.
IN T34365 Hp1-alpha; human, Homo sapiens.
IN T28743 Hp1-gamma; human, Homo sapiens.
IN T09395 IRF-7; human, Homo sapiens.
IN T04674 IRF-7A; human, Homo sapiens.
IN T00862 LBP-1; human, Homo sapiens.
IN T18835 Mi2-alpha; human, Homo sapiens.
IN T09162 Pax-3; mouse, Mus musculus.
IN T08711 RelA-p65; human, Homo sapiens.
IN T30231 SIRT1-isoform1; human, Homo sapiens.
IN T00811 TFEA; human, Homo sapiens.
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MX M01199 V$RNF96_01.
MX M04925 V$TRIM28_02.
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DR TRANSPATH: MO000069886.
DR UniProtKB: Q13263; TIF1B_HUMAN.
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RN [1]; RE0038639.
RX PUBMED: 11959841.
RA Schultz D. C., Ayyanathan K., Negorev D., Maul G. G., Rauscher F. J. 3rd.
RT SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
RL Genes Dev. 16:919-32 (2002).
RN [2]; RE0048806.
RX PUBMED: 17079232.
RA Lee Y. K., Thomas S. N., Yang A. J., Ann D. K.
RT Doxorubicin downregulates KAP1 SUMOylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells.
RL J. Biol. Chem. 282:1595-1606 (2006).
RN [3]; RE0049039.
RX PUBMED: 16107876.
RA Wang C., Ivanov A., Chen L., Fredericks W. J., Seto E., Rauscher FJ 3. r. d., Chen J.
RT MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation.
RL EMBO J. 24:3279-3290 (2005).
RN [4]; RE0063261.
RX PUBMED: 16169070.
RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E.
RT A human protein-protein interaction network: a resource for annotating the proteome.
RL Cell 122:957-968 (2005).
RN [5]; RE0065167.
RX PUBMED: 19377469.
RA Tian C., Xing G., Xie P., Lu K., Nie J., Wang J., Li L., Gao M., Zhang L., He F.
RT KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.
RL Nat. Cell Biol. 11:580-591 (2009).
RN [6]; RE0066950.
RX PUBMED: 16945326.
RA Hsieh M. J., Yao Y. L., Lai I. L., Yang W. M.
RT Transcriptional repression activity of PAX3 is modulated by competition between corepressor KAP1 and heterochromatin protein 1.
RL Biochem. Biophys. Res. Commun. 349:573-581 (2006).
RN [7]; RE0072499.
RX PUBMED: 18675275.
RA Okazaki N., Ikeda S., Ohara R., Shimada K., Yanagawa T., Nagase T., Ohara O., Koga H.
RT The novel protein complex with SMARCAD1/KIAA1122 binds to the vicinity of TSS.
RL J. Mol. Biol. 382:257-265 (2008).
RN [8]; RE0072566.
RX PUBMED: 21549307.
RA Rowbotham S. P., Barki L., Neves-Costa A., Santos F., Dean W., Hawkes N., Choudhary P., Will W. R., Webster J., Oxley D., Green C. M., Varga-Weisz P., Mermoud J. E.
RT Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.
RL Mol. Cell 42:285-296 (2011).
RN [9]; RE0074383.
RX PUBMED: 19112178.
RA Zhang L. J., Liu X., Gafken P. R., Kioussi C., Leid M.
RT A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).
RL J. Biol. Chem. 284:6156-6168 (2009).
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