AC T33762
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ID T33762
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DT 20.11.2002 (created); cch.
DT 30.07.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA DRIP205
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SY Activator-recruited cofactor 205 kDa component; ARC205; CRSP1; CRSP200; DRIP205; DRIP230; p53 regulatory protein RB18A; PBP; peroxisome proliferator-activated receptor binding protein; Peroxisome proliferator-activated receptor-binding protein; PPAR binding protein; PPAR-binding protein; PPARBP; PPARGBP; RB18A; thyroid hormone receptor interactor 2; Thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; Thyroid receptor-interacting protein 2; TRAP220; TRIP-2; TRIP2; vitamin D receptor-interacting protein complex component DRIP205.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004939 MED1; HGNC: MED1.
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IN T08487 AR-isoform1; human, Homo sapiens.
IN T00040 AR; human, Homo sapiens.
IN T01488 Cdk2; human, Homo sapiens.
IN T17935 FXR:RXR-alpha; Mammalia.
IN T09632 FXR; human, Homo sapiens.
IN T02368 HMGIY; human, Homo sapiens.
IN T04453 LXR-beta; human, Homo sapiens.
IN T05351 PPARgamma; human, Homo sapiens.
IN T08711 RelA-p65; human, Homo sapiens.
IN T08433 RXR-alpha; human, Homo sapiens.
IN T05368 SRB7; human, Homo sapiens.
IN T01152 T3R-alpha1; human, Homo sapiens.
IN T00853 T3R-beta1; rat, Rattus norvegicus.
IN T04995 ZBP99; human, Homo sapiens.
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BS R72634.
BS R72639.
BS R72644.
BS R72648.
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DR TRANSPATH: MO000033692.
DR UniProtKB: Q15648;
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RN [1]; RE0018254.
RX PUBMED: 12037571.
RA Ge K., Guermah M., Yuan C. X., Ito M., Wallberg A. E., Spiegelman B. M., Roeder R. G.
RT Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.
RL Nature 417:563-567 (2002).
RN [2]; RE0025974.
RX PUBMED: 9653119.
RA Yuan C. X., Ito M., Fondell J. D., Fu Z. Y., Roeder R. G.
RT The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
RL Proc. Natl. Acad. Sci. USA 95:7939-44 (1998).
RN [3]; RE0029988.
RX PUBMED: 12218053.
RA Wang Q., Sharma D., Ren Y., Fondell J. D.
RT A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression.
RL J. Biol. Chem. 277:42852-8 (2002).
RN [4]; RE0030588.
RX PUBMED: 14636573.
RA Wallberg A. E., Yamamura S., Malik S., Spiegelman B. M., Roeder R. G.
RT Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.
RL Mol. Cell 12:1137-49 (2003).
RN [5]; RE0047744.
RX PUBMED: 7776974.
RA Lee J. W., Choi H. S., Gyuris J., Brent R., Moore D. D.
RT Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.
RL Mol. Endocrinol. 9:243-254 (1995).
RN [6]; RE0050526.
RX PUBMED: 11027271.
RA Yang W., Rachez C., Freedman L. P.
RT Discrete roles for peroxisome proliferator-activated receptor gamma and retinoid X receptor in recruiting nuclear receptor coactivators.
RL Mol. Cell. Biol. 20:8008-8017 (2000).
RN [7]; RE0051051.
RX PUBMED: 15187081.
RA Pineda Torra I., Freedman L. P., Garabedian M. J.
RT Identification of DRIP205 as a coactivator for the Farnesoid X receptor.
RL J. Biol. Chem. 279:36184-36191 (2004).
RN [8]; RE0054989.
RX PUBMED: 15604093.
RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M.
RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
RL Mol. Cell. Proteomics 4:205-213 (2005).
RN [9]; RE0073074.
RX PUBMED: 22102282.
RA Jin F., Claessens F., Fondell J. D.
RT Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif.
RL J. Biol. Chem. 287:858-870 (2012).
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