AC T05839
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ID T05839
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DT 04.02.2004 (created); elf.
DT 21.08.2014 (updated); hna.
CO Copyright (C), QIAGEN.
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FA DEC2
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SY basic helix-loop-helix domain containing, class B, 3; Bhlhb3; dec2; Differentially expressed in chondrocytes protein 2; Enhancer-of-split and hairy-related protein 1; SHARP-1; Sharp1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009149 BHLHE41; HGNC: Bhlhe41.
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CL C0010; bHLH; 1.2.4.1.13.
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SF lacks the WRPW motif for interaction with the corepressor Groucho [1];
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IN T01610 HIF-1alpha; human, Homo sapiens.
IN T08711 RelA-p65; human, Homo sapiens.
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MX M01843 V$DEC2_Q2.
MX M08871 V$DEC2_Q3.
MX M00997 V$DEC_Q1.
MX M08872 V$DEC_Q3.
MX M01034 V$EBOX_Q6_01.
MX M08885 V$HAIRYLIKE_Q3.
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BS R63391.
BS R63532.
BS R63440.
BS R63467.
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DR TRANSPATH: MO000039155.
DR UniProtKB: Q9C0J9;
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RN [1]; RE0023788.
RX PUBMED: 11162494.
RA Fujimoto K., Shen M., Noshiro M., Matsubara K., Shingu S., Honda K., Yoshida E., Suardita K., Matsuda Y., Kato Y.
RT Molecular cloning and characterization of DEC2, a new member of basic helix-loop-helix proteins.
RL Biochem. Biophys. Res. Commun. 280:164-171 (2001).
RN [2]; RE0023876.
RX PUBMED: 12397359.
RA Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., Honma K.
RT Dec1 and Dec2 are regulators of the mammalian molecular clock.
RL Nature 419:841-844 (2002).
RN [3]; RE0066549.
RX PUBMED: 18345027.
RA Nakamura H., Tanimoto K., Hiyama K., Yunokawa M., Kawamoto T., Kato Y., Yoshiga K., Poellinger L., Hiyama E., Nishiyama M.
RT Human mismatch repair gene, MLH1, is transcriptionally repressed by the hypoxia-inducible transcription factors, DEC1 and DEC2.
RL Oncogene 27:4200-4209 (2008).
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