AC T10210
XX
ID T10210
XX
DT 02.02.2007 (created); man.
DT 01.09.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA Evi-1
XX
SY AML1-EVI-1; ecotropic viral integration site 1; ecotropic virus integration 1 site protein; ectropic viral integration site-1; EVI1; hCG_1640438; MDS1; MDS1 and EVI1 complex locus; MDS1-EVI1; MECOM; MGC163392; MGC97004; oncogene EVI1; PRDM3.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G004729 MECOM; HGNC: MECOM.
XX
CL C0001; CH; 2.3.4.14.1.1.
XX
SZ 1051 AA; 118.3 kDa (calc.).
XX
SQ MKSEDYPHETMAPDIHEERQYRCEDCDQLFESKAELADHQKFPCSTPHSAFSMVEEDFQQ
SQ KLESENDLQEIHTIQECKECDQVFPDLQSLEKHMLSHTEEREYKCDQCPKAFNWKSNLIR
SQ HQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFATSSGLKQHKH
SQ IHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTSSLNKHRRFCE
SQ GKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGANRHPAGLTFPTAPGFS
SQ FSVPGLFPSGLYHRPPLIPASSPVKGLSSTEQTNKSQSPLMTHPQILPATQDILKALSKH
SQ PSVGDNKPVELQPERSSEERPFEKISDQSESSDLDDVSTPSGSDLETTSGSDLESDIESD
SQ KEKFKENGKMFKDKVSPLQNLASINNKKEYSNHSIFSPSLEEQTAVSGAVNDSIKAIASI
SQ AEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSLPLKMEPQSPG
SQ EVKKLQKGSSESPFDLTTKRKDEKPLTPVPSKPPVTPATSQDQPLDLSMGSRSRASGTKL
SQ TEPRKNHVFGGKKGSNVESRPASDGSLQHARPTPFFMDPIYRVEKRKLTDPLEALKEKYL
SQ RPSPGFLFHPQFQLPDQRTWMSAIENMAEKLESFSALKPEASELLQSVPSMFNFRAPPNA
SQ LPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRHV
SQ RNIHNKEKPFKCHLCYRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESTGAILDDKE
SQ DAYFTEIRNFIGNSNHGSQSPRNVEERMNGSHFKEEKALVPSQNSDLLDDEEVEDEVLLD
SQ EEDEDYDITGKTGKEPVTSNLHEGNPEDDYEETSALEMSCKTSPVRYKEEEYKSGLSALD
SQ HIRHFTDSLKMRKMEDNQYSEAELSSFSTSHVPEELKQPLHRKSKSQAYAMMLSLSDKES
SQ LHSTSHSSSNVWHSMARAAAESSAIQSISHV
XX
SC translated from EMBL #X54989
XX
FT 21 41 
SM00355; c2h2final6.
FT 21 44 
PF00096; zf-C2H2.
FT 21 49 
PS50157; ZINC_FINGER_C2H2_2.
FT 75 97 
PF00096; zf-C2H2.
FT 75 97 
SM00355; c2h2final6.
FT 75 102 
PS50157; ZINC_FINGER_C2H2_2.
FT 103 125 
PF00096; zf-C2H2.
FT 103 125 
SM00355; c2h2final6.
FT 103 130 
PS50157; ZINC_FINGER_C2H2_2.
FT 131 154 
PF00096; zf-C2H2.
FT 131 154 SM00355; c2h2final6.
FT 131 159 PS50157; ZINC_FINGER_C2H2_2.
FT 160 182 PF00096; zf-C2H2.
FT 160 182 SM00355; c2h2final6.
FT 160 187 PS50157; ZINC_FINGER_C2H2_2.
FT 188 210 PF00096; zf-C2H2.
FT 188 210 SM00355; c2h2final6.
FT 188 215 PS50157; ZINC_FINGER_C2H2_2.
FT 217 239 PF00096; zf-C2H2.
FT 217 244 PS50157; ZINC_FINGER_C2H2_2.
FT 217 244 SM00355; c2h2final6.
FT 309 1050 PF00478; IMP dehydrogenase / GMP reductase domain.
FT 733 755 PF00096; zf-C2H2.
FT 733 755 SM00355; c2h2final6.
FT 733 760 PS50157; ZINC_FINGER_C2H2_2.
FT 761 784 PF00096; zf-C2H2.
FT 761 784 SM00355; c2h2final6.
FT 761 789 PS50157; ZINC_FINGER_C2H2_2.
FT 790 812 PF00096; zf-C2H2.
FT 790 812 SM00355; c2h2final6.
FT 790 817 PS50157; ZINC_FINGER_C2H2_2.
XX
IN T05109 53BP1; human, Homo sapiens.
IN T19734 ADNP; human, Homo sapiens.
IN T18770 ARID1B; human, Homo sapiens.
IN T22426 BAF170; human, Homo sapiens.
IN T22424 BAF57; human, Homo sapiens.
IN T15118 CBP; Mammalia.
IN T09585 CREM; human, Homo sapiens.
IN T05222 CtBP1; human, Homo sapiens.
IN T10784 CtBP1; Mammalia.
IN T06040 CtBP2; human, Homo sapiens.
IN T03238 DDB1; human, Homo sapiens.
IN T01991 Fra-2; human, Homo sapiens.
IN T27167 GATAD2B; human, Homo sapiens.
IN T25630 HCF1; human, Homo sapiens.
IN T04106 HDAC1; human, Homo sapiens.
IN T21852 HDAC1; Mammalia.
IN T25625 hdac2; human, Homo sapiens.
IN T01977 JunB; human, Homo sapiens.
IN T05110 Ku70; human, Homo sapiens.
IN T05111 Ku80; human, Homo sapiens.
IN T34374 Mi2-BETA; human, Homo sapiens.
IN T06148 p/CAF; human, Homo sapiens.
IN T14055 PARP; human, Homo sapiens.
IN T17041 PEBP2beta; human, Homo sapiens.
IN T03214 Pontin52; human, Homo sapiens.
IN T34267 ptrf; human, Homo sapiens.
IN T10397 RelA-p65; Mammalia.
IN T28756 SMC-3; human, Homo sapiens.
IN T28176 SMC1; human, Homo sapiens.
IN T22463 SNF2H; human, Homo sapiens.
IN T28757 TBLR1; human, Homo sapiens.
IN T00824 TFII-I; human, Homo sapiens.
IN T17430 TRPS1; human, Homo sapiens.
IN T08660 YY1; human, Homo sapiens.
IN T10300 ZBP89; human, Homo sapiens.
IN T04995 ZBP99; human, Homo sapiens.
IN T20709 ZNF516; human, Homo sapiens.
XX
MX M00078 V$EVI1_01.
MX M00079 V$EVI1_02.
MX M00080 V$EVI1_03.
MX M00081 V$EVI1_04.
MX M00082 V$EVI1_05.
MX M00011 V$EVI1_06.
MX M02002 V$EVI1_Q3.
MX M07604 V$EVI_Q6.
XX
BS R31847.
XX
DR TRANSPATH: MO000098026.
DR EMBL: S69002; S69002.
DR EMBL: S82592; S82592.
DR EMBL: X54989; MMEVI1A.
DR UniProtKB: Q03112-1;
XX
RN [1]; RE0021458.
RX PUBMED: 10856240.
RA Kurokawa M., Mitani K., Yamagata T., Takahashi T., Izutsu K., Ogawa S., Moriguchi T., Nishida E., Yazaki Y., Hirai H.
RT The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death
RL EMBO J. 19:2958-2968 (2000).
RN [2]; RE0029363.
RX PUBMED: 11568182.
RA Chakraborty S., Senyuk V., Sitailo S., Chi Y., Nucifora G.
RT Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles.
RL J. Biol. Chem. 276:44936-43 (2001).
XX
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