AC T28757
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ID T28757
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DT 17.10.2006 (created); sou.
DT 22.12.2014 (updated); sup.
CO Copyright (C), QIAGEN.
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FA TBLR1
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SY F-box-like/WD repeat protein TBL1XR1; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; TBL1XR1; Transducin beta-like 1X-related protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G037559 TBL1XR1; HGNC: TBL1XR1.
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IN T01928 Bcl-3; human, Homo sapiens.
IN T17532 Bcl-3; Mammalia.
IN T22468 BCL11A-isoform1; human, Homo sapiens.
IN T08505 COUP-TF1; human, Homo sapiens.
IN T05220 Evi-1; human, Homo sapiens.
IN T10210 Evi-1; human, Homo sapiens.
IN T34374 Mi2-BETA; human, Homo sapiens.
IN T04687 NCOR1; human, Homo sapiens.
IN T04689 SMRT; human, Homo sapiens.
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BS R65368.
BS R65369.
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DR TRANSPATH: MO000089301.
DR UniProtKB: Q9BZK7;
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RN [1]; RE0036641.
RX PUBMED: 12628926.
RA Yoon H. G., Chan D. W., Huang Z. Q., Li J., Fondell J. D., Qin J., Wong J.
RT Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
RL EMBO J. 22:1336-1346 (2003).
RN [2]; RE0048529.
RX PUBMED: 14527417.
RA Yoon H. G., Chan D. W., Reynolds A. B., Qin J., Wong J.
RT N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.
RL Mol. Cell 12:723-734 (2003).
RN [3]; RE0048630.
RX PUBMED: 15601853.
RA Yoon H. G., Choi Y., Cole P. A., Wong J.
RT Reading and function of a histone code involved in targeting corepressor complexes for repression.
RL Mol. Cell. Biol. 25:324-35 (2005).
RN [4]; RE0070618.
RX PUBMED: 20547759.
RA Keutgens A., Shostak K., Close P., Zhang X., Hennuy B., Aussems M., Chapelle J. P., Viatour P., Gothot A., Fillet M., Chariot A.
RT The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.
RL Mol. Cell. Biol. 30:4006-4021 (2010).
RN [5]; RE0074383.
RX PUBMED: 19112178.
RA Zhang L. J., Liu X., Gafken P. R., Kioussi C., Leid M.
RT A chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) complex represses expression of the gene encoding tumor necrosis factor alpha-induced protein 8 (TNFAIP8).
RL J. Biol. Chem. 284:6156-6168 (2009).
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