AC T00824
AS T04130.
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ID T00824
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DT 21.10.1992 (created); ewi.
DT 14.08.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA TFII-I
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SY BAP-135; BAP135; BTKAP1; DIWS; FLJ38776; FLJ56355; general transcription factor II, i; General Transcription Factor II-I; General transcription factor III; GTF2I; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005301 GTF2I; HGNC: GTF2I.
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FF binds to initiator regions (Inr), cooperates with USF;
FF interaction with Phox1 and SRF in vitro and in vivo [2];
FF promotes the formation of Phox1-dependent signal responsive complexes on the SRE [2];
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IN T05220 Evi-1; human, Homo sapiens.
IN T10210 Evi-1; human, Homo sapiens.
IN T08343 HDAC1; human, Homo sapiens.
IN T04110 HDAC3; human, Homo sapiens.
IN T00764 SRF; human, Homo sapiens.
IN T01575 STAT1alpha; mouse, Mus musculus.
IN T01493 STAT3; human, Homo sapiens.
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MX M00706 V$TFIII_Q6.
MX M04636 V$TFIII_Q6_01.
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BS R00992.
BS R02081.
BS R09697.
BS R09698.
BS R31855.
BS R59089.
BS R59237.
BS R59238.
BS R59239.
BS R62013.
BS R69252.
BS R69253.
BS R09690.
BS R09691.
BS R09692.
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DR TRANSPATH: MO000019622.
DR UniProtKB: P78347; GTFI_HUMAN.
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RN [1]; RE0001862.
RX PUBMED: 1961251.
RA Roy A. L., Meisterernst M., Pognonec P., Roeder R. G.
RT Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF
RL Nature 354:245-248 (1991).
RN [2]; RE0015496.
RX PUBMED: 9334314.
RA Grueneberg D. A., Henry R. W., Brauer A., Novina C. D., Cheriyath V., Roy A.L., Gilman M.
RT A multifunctional DNA-binding protein that promotes the formation of serum response factor/homeodomain complexes: identity to TFII-I
RL Genes Dev. 11:2482-2493 (1997).
RN [3]; RE0022659.
RX PUBMED: 11313464.
RA Kim D. W., Cochran B. H.
RT JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase.
RL Mol. Cell. Biol. 21:3387-3397 (2001).
RN [4]; RE0038035.
RX PUBMED: 12393887.
RA Wen Y. D., Cress W. D., Roy A. L., Seto E.
RT Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I
RL J. Biol. Chem. 278:1841-7 (2003).
RN [5]; RE0048045.
RX PUBMED: 14623887.
RA Sacristan C., Tussie-Luna M. I., Logan S. M., Roy A. L.
RT Mechanism of Bruton's tyrosine kinase-mediated recruitment and regulation of TFII-I.
RL J. Biol. Chem. 279:7147-7158 (2004).
RN [6]; RE0070139.
RX PUBMED: 19701889.
RA Sacristan C., Schattgen S. A., Berg L. J., Bunnell S. C., Roy A. L., Rosenstein Y.
RT Characterization of a novel interaction between transcription factor TFII-I and the inducible tyrosine kinase in T cells.
RL Eur. J. Immunol. 39:2584-2595 (2009).
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