TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05109 XX ID T05109 XX DT 14.05.2002 (created); cch. DT 30.09.2014 (updated); yre. CO Copyright (C), QIAGEN. XX FA 53BP1 XX SY p53 tumor suppressor-binding protein 1; p53-binding protein 1; TPBP. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G009085 TP53BP1; HGNC: TP53BP1. XX IN T02727 cyclinT1; human, Homo sapiens. IN T05220 Evi-1; human, Homo sapiens. IN T10210 Evi-1; human, Homo sapiens. IN T21984 p300; human, Homo sapiens. IN T00671 p53; human, Homo sapiens. IN T01806 p53; mouse, Mus musculus. XX BS R21815. BS R21817. BS R21818. XX DR TRANSPATH: MO000023613. DR UniProtKB: Q12888; P531_HUMAN. XX RN [1]; RE0017778. RX PUBMED: 11877378. RA Joo W. S., Jeffrey P. D., Cantor S. B., Finnin M. S., Livingston D. M., Pavletich N. P. RT Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. RL Genes Dev. 16:583-593 (2002). RN [2]; RE0047817. RX PUBMED: 15364958. RA Sengupta S., Robles A. I., Linke S. P., Sinogeeva N. I., Zhang R., Pedeux R., Ward I. M., Celeste A., Nussenzweig A., Chen J., Halazonetis T. D., Harris C. C. RT Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest. RL J. Cell Biol. 166:801-813 (2004). RN [3]; RE0048799. RX PUBMED: 14690447. RA Surpili M. J., Delben T. M., Kobarg J. RT Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1. RL Biochemistry 42:15369-15376 (2003). RN [4]; RE0049880. RX PUBMED: 14985081. RA Cao Y., Hamada T., Matsui T., Date T., Iwabuchi K. RT Hepatitis C virus core protein interacts with p53-binding protein, 53BP2/Bbp/ASPP2, and inhibits p53-mediated apoptosis. RL Biochem. Biophys. Res. Commun. 315:788-795 (2004). RN [5]; RE0063261. RX PUBMED: 16169070. RA Stelzl U., Worm U., Lalowski M., Haenig C., Brembeck F. H., Goehler H., Stroedicke M., Zenkner M., Schoenherr A., Koeppen S., Timm J., Mintzlaff S., Abraham C., Bock N., Kietzmann S., Goedde A., Toksoz E., Droege A., Krobitsch S., Korn B., Birchmeier W., Lehrach H., Wanker E. E. RT A human protein-protein interaction network: a resource for annotating the proteome. RL Cell 122:957-968 (2005). RN [6]; RE0065929. RX PUBMED: 20016603. RA Galanty Y., Belotserkovskaya R., Coates J., Polo S., Miller K. M., Jackson S. P. RT Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. RL Nature 462:935-939 (2009). RN [7]; RE0069452. RX PUBMED: 21149733. RA Gurvich N., Perna F., Farina A., Voza F., Menendez S., Hurwitz J., Nimer S. D. RT L3MBTL1 polycomb protein, a candidate tumor suppressor in del(20q12) myeloid disorders, is essential for genome stability. RL Proc. Natl. Acad. Sci. USA 107:22552-22557 (2010). RN [8]; RE0021239. RX PUBMED: 11331310. RA Rappold I., Iwabuchi K., Date T., Chen J. RT Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways RL J. Cell Biol. 153:613-620 (2001). XX //