TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05222 XX ID T05222 XX DT 16.09.2002 (created); cch. DT 04.09.2014 (updated); pos. CO Copyright (C), QIAGEN. XX FA CtBP1 XX SY C-terminal binding protein; C-terminal binding protein 1. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004732 CTBP1; HGNC: CTBP1. XX IN T17532 Bcl-3; Mammalia. IN T05222 CtBP1; human, Homo sapiens. IN T06040 CtBP2; human, Homo sapiens. IN T05220 Evi-1; human, Homo sapiens. IN T10210 Evi-1; human, Homo sapiens. IN T10390 FKLF-isoform1; human, Homo sapiens. IN T14726 FOG; mouse, Mus musculus. IN T06429 HIC-1-isoform2; human, Homo sapiens. IN T10980 KLF3; mouse, Mus musculus. IN T04220 Smad6; human, Homo sapiens. IN T15704 SNA; Mammalia. IN T02918 TCF-4; human, Homo sapiens. IN T03915 ZEB; mouse, Mus musculus. XX MX M07317 V$CTBP1_Q3. XX BS R63533. BS R63436. BS R63459. XX DR TRANSPATH: MO000033257. DR UniProtKB: Q13363; CTB1_HUMAN. XX RN [1]; RE0031933. RX PUBMED: 14645520. RA Lin X., Liang Y. Y., Sun B., Liang M., Shi Y., Brunicardi F. C., Shi Y., Feng X. H. RT Smad6 recruits transcription corepressor CtBP to repress bone morphogenetic protein-induced transcription. RL Mol. Cell. Biol. 23:9081-93 (2003). RN [2]; RE0044524. RX PUBMED: 12679040. RA Kagey M. H., Melhuish T. A., Wotton D. RT The polycomb protein Pc2 is a SUMO E3 RL Cell 113:127-37 (2003). RN [3]; RE0049097. RX PUBMED: 16508011. RA Paliwal S., Pande S., Kovi R. C., Sharpless N. E., Bardeesy N., Grossman S. R. RT Targeting of C-terminal binding protein (CtBP) by ARF results in p53-independent apoptosis. RL Mol. Cell. Biol. 26:2360-2372 (2006). RN [4]; RE0067182. RX PUBMED: 20547755. RA Van Rechem C., Boulay G., Pinte S., Stankovic-Valentin N., Guerardel C., Leprince D. RT Differential regulation of HIC1 target genes by CtBP and NuRD, via an Acetylation/SUMOylation switch, in quiescent versus proliferating cells. RL Mol. Cell. Biol. 30:4045-4059 (2010). RN [5]; RE0070618. RX PUBMED: 20547759. RA Keutgens A., Shostak K., Close P., Zhang X., Hennuy B., Aussems M., Chapelle J. P., Viatour P., Gothot A., Fillet M., Chariot A. RT The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1. RL Mol. Cell. Biol. 30:4006-4021 (2010). XX //