AC T28176
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ID T28176
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DT 13.09.2004 (created); mkl.
DT 16.12.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA SMC1
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SY CDLS2; DKFZp686L19178; DXS423E; KIAA0178; MGC138332; RP6-29D12.1; SB1.8; SMC1; SMC1 structural maintenance of chromosomes 1-like 1 (yeast); Smc1a; SMC1alpha; SMC1L1; SMCB; structural maintenance of chromosomes 1A.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009973 SMC1A; HGNC: Smc1a.
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IN T05220 Evi-1; human, Homo sapiens.
IN T10210 Evi-1; human, Homo sapiens.
IN T34277 mcm7; human, Homo sapiens.
IN T18009 Rad21; human, Homo sapiens.
IN T22425 RCOR1; human, Homo sapiens.
IN T28756 SMC-3; human, Homo sapiens.
IN T09133 YY1; Mammalia.
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BS R56236.
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DR TRANSPATH: MO000043750.
DR UniProtKB: Q14683;
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RN [1]; RE0027287.
RX PUBMED: 11076961.
RA Sumara I., Vorlaufer E., Gieffers C., Peters B. H., Peters J. M.
RT Characterization of Vertebrate Cohesin Complexes and Their Regulation in Prophase.
RL J. Cell Biol. 151:749-762 (2000).
RN [2]; RE0029444.
RX PUBMED: 11590136.
RA Gregson H. C., Schmiesing J. A., Kim J. S., Kobayashi T., Zhou S., Yokomori K.
RT A potential role for human cohesin in mitotic spindle aster assembly.
RL J. Biol. Chem. 276:47575-82 (2001).
RN [3]; RE0048218.
RX PUBMED: 16226712.
RA Niture S. K., Doneanu C. E., Velu C. S., Bailey N. I., Srivenugopal K. S.
RT Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry.
RL Biochem. Biophys. Res. Commun. 337:1176-1184 (2005).
RN [4]; RE0049499.
RX PUBMED: 17113138.
RA Kueng S., Hegemann B., Peters B. H., Lipp J. J., Schleiffer A., Mechtler K., Peters J. M.
RT Wapl controls the dynamic association of cohesin with chromatin.
RL Cell 127:955-967 (2006).
RN [5]; RE0050410.
RX PUBMED: 17349791.
RA Schmitz J., Watrin E., Lenart P., Mechtler K., Peters J. M.
RT Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
RL Curr. Biol. 17:630-636 (2007).
RN [6]; RE0050412.
RX PUBMED: 15837422.
RA Rankin S., Ayad N. G., Kirschner M. W.
RT Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.
RL Mol. Cell 18:185-200 (2005).
RN [7]; RE0050985.
RX PUBMED: 15737063.
RA Hauf S., Roitinger E., Koch B., Dittrich C. M., Mechtler K., Peters J. M.
RT Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.
RL PLoS Biol. 3:e69 (2005).
RN [8]; RE0051072.
RX PUBMED: 16159877.
RA McCracken S., Longman D., Marcon E., Moens P., Downey M., Nickerson J. A., Jessberger R., Wilde A., Caceres J. F., Emili A., Blencowe B. J.
RT Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin.
RL J. Biol. Chem. 280:42227-42236 (2005).
RN [9]; RE0053727.
RX PUBMED: 16377563.
RA Stucki M., Clapperton J. A., Mohammad D., Yaffe M. B., Smerdon S. J., Jackson S. P.
RT MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks.
RL Cell 123:1213-1226 (2005).
RN [10]; RE0070169.
RX PUBMED: 20123963.
RA Kodama M., Otsubo C., Hirota T., Yokota J., Enari M., Taya Y.
RT Requirement of ATM for rapid p53 phosphorylation at Ser46 without Ser/Thr-Gln sequences.
RL Mol. Cell. Biol. 30:1620-1633 (2010).
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