AC T28776
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ID T28776
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DT 17.10.2006 (created); sou.
DT 15.07.2011 (updated); pos.
CO Copyright (C), QIAGEN.
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FA TBLR1
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SY F-box-like/WD repeat protein TBL1XR1; IRA1; Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; TBL1XR1; Transducin beta-like 1X-related protein 1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G037559 TBL1XR1; HGNC: TBL1XR1.
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SZ 514 AA; 55.6 kDa (cDNA) (calc.).
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SQ MSISSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGALVPPAALISIIQKGLQYV
SQ EAEVSINEDGTLFDGRPIESLSLIDAVMPDVVQTRQQAYRDKLAQQQAAAAAAAAAAASQ
SQ QGSAKNGENTANGEENGAHTIANNHTDMMEVDGDVEIPPNKAVVLRGHESEVFICAWNPV
SQ SDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKDVTSLDWNSEGTLL
SQ ATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEA
SQ KQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPT
SQ GNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASF
SQ DSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSY
SQ RGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK
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SC Swiss-Prot#Q9BZK7
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FT 4 36 PS50896; LISH.
FT 4 36 SM00667; Lish.
FT 6 32 PF08513; LisH.
FT 158 197 SM00320; WD40_4.
FT 159 197 PF00400; WD40.
FT 165 206 PS50082; WD_REPEATS_2.
FT 165 479 PS50294; WD_REPEATS_REGION.
FT 208 253 SM00320; WD40_4.
FT 216 253 PF00400; WD40.
FT 228 252 PS50082; WD_REPEATS_2.
FT 255 294 SM00320; WD40_4.
FT 256 294 PF00400; WD40.
FT 262 303 PS50082; WD_REPEATS_2.
FT 297 335 SM00320; WD40_4.
FT 298 335 PF00400; WD40.
FT 338 377 SM00320; WD40_4.
FT 339 377 PF00400; WD40.
FT 345 386 PS50082; WD_REPEATS_2.
FT 380 428 SM00320; WD40_4.
FT 381 428 PF00400; WD40.
FT 387 437 PS50082; WD_REPEATS_2.
FT 431 470 SM00320; WD40_4.
FT 432 470 PF00400; WD40.
FT 438 479 PS50082; WD_REPEATS_2.
FT 473 511 SM00320; WD40_4.
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IN T17532 Bcl-3; Mammalia.
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DR TRANSPATH: MO000089299.
DR UniProtKB: Q9BZK7;
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RN [1]; RE0070618.
RX PUBMED: 20547759.
RA Keutgens A., Shostak K., Close P., Zhang X., Hennuy B., Aussems M., Chapelle J. P., Viatour P., Gothot A., Fillet M., Chariot A.
RT The repressing function of the oncoprotein BCL-3 requires CtBP, while its polyubiquitination and degradation involve the E3 ligase TBLR1.
RL Mol. Cell. Biol. 30:4006-4021 (2010).
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