AC T14002
XX
ID T14002
XX
DT 01.02.2008 (created); nta.
DT 23.06.2015 (updated); pro.
CO Copyright (C), QIAGEN.
XX
FA GKLF
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SY epithelial zinc-finger protein; EZF; gut-enriched Krueppel-like factor; KLF4; Krueppel-like factor 4; ZIE.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G006344 Klf4.
XX
CL C0001; CH; 2.3.1.2.4.2.
XX
SZ 483 AA; 51.9 kDa (cDNA) (calc.).
XX
SQ MRQPPGESDMAVSDALLPSFSTFASGPAGREKTLRPAGAPTNRWREELSHMKRLPPLPGR
SQ PYDLAATVATDLESGGAGAACSSNNPALLARRETEEFNDLLDLDFILSNSLTHQESVAAT
SQ VTTSASASSSSSPASSGPASAPSTCSFSYPIRAGGDPGVAASNTGGGLLYSRESAPPPTA
SQ PFNLADINDVSPSGGFVAELLRPELDPVYIPPQQPQPPGGGLMGKFVLKASLTTPGSEYS
SQ SPSVISVSKGSPDGSHPVVVAPYSGGPPRMCPKIKQEAVPSCTVSRSLEAHLSAGPQLSN
SQ GHRPNTHDFPLGRQLPTRTTPTLSPEELLNSRDCHPGLPLPPGFHPHPGPNYPPFLPDQM
SQ QSQVPSLHYQELMPPGSCLPEEPKPKRGRRSWPRKRTATHTCDYAGCGKTYTKSSHLKAH
SQ LRTHTGEKPYHCDWDGCGWKFARSDELTRHYRKHTGHRPFQCQKCDRAFSRSDHLALHMK
SQ RHF
XX
SC SPTREMBL #Q60793
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FT 1 9 missing in sequence of [2].
FT 400 424 PF00096; zf-C2H2.
FT 400 424 SM00355; c2h2final6.
FT 400 429 PS50157; ZINC_FINGER_C2H2_2.
FT 430 454 PF00096; zf-C2H2.
FT 430 454 SM00355; c2h2final6.
FT 430 459 PS50157; ZINC_FINGER_C2H2_2.
FT 460 482 PF00096; zf-C2H2.
FT 460 482 SM00355; c2h2final6.
FT 460 483 PS50157; ZINC_FINGER_C2H2_2.
XX
IN T02872 beta-catenin; human, Homo sapiens.
IN T14513 beta-catenin; Mammalia.
IN T23091 p300; Mammalia.
IN T05329 PPARgamma; rat, Rattus norvegicus.
IN T00754 Sp1; rat, Rattus norvegicus.
XX
MX M01588 V$GKLF_02.
MX M07040 V$GKLF_Q3.
MX M07289 V$GKLF_Q3_01.
MX M01835 V$GKLF_Q4.
MX M07461 V$KLF_Q3.
XX
BS R05008.
BS R10746.
BS R10747.
BS R10748.
BS R10749.
BS R10750.
BS R10751.
BS R10752.
BS R10753.
BS R10754.
BS R10755.
BS R10756.
BS R10757.
BS R10758.
BS R10759.
BS R10760.
BS R10761.
BS R10762.
BS R10763.
BS R10764.
BS R10765.
BS R10766.
BS R10767.
BS R10768.
BS R10769.
BS R10770.
BS R10771.
BS R10772.
BS R10773.
BS R10774.
BS R10775.
BS R10776.
BS R10777.
BS R10778.
BS R10779.
BS R10780.
BS R10781.
BS R10782.
BS R10783.
BS R10784.
BS R10785.
BS R10786.
BS R10787.
BS R10788.
BS R10789.
BS R10790.
BS R10791.
BS R10792.
BS R10793.
BS R10794.
BS R15645.
BS R15646.
BS R15647.
BS R15648.
BS R33526.
BS R33527.
BS R33528.
BS R35472.
BS R35475.
BS R23052.
BS R68502.
BS R33487.
BS R35496.
BS R35497.
BS R67035.
BS R67036.
BS R67037.
BS R67039.
BS R67040.
BS R67041.
BS R67042.
BS R67043.
BS R66629.
BS R15644.
XX
DR TRANSPATH: MO000121833.
DR EMBL: U20344;
DR EMBL: U70662;
DR UniProtKB: Q60793;
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RN [1]; RE0006854.
RX PUBMED: 8702718.
RA Shields J. M., Christy R. J., Yang V. W.
RT Identification and characterization of a gene encoding a gut-enriched Kruppel-like factor expressed during growth arrest
RL J. Biol. Chem. 271:20009-20017 (1996).
RN [2]; RE0006856.
RX PUBMED: 8940147.
RA Garrett-Sinha L. A., Eberspaecher H., Seldin M. F., Crombrugghe B.
RT A gene for a novel zinc-finger protein expressed in differentiated epithelial cells and transiently in certain mesenchymal cells
RL J. Biol. Chem. 271:31384-31390 (1996).
RN [3]; RE0006857.
RX PUBMED: 9443972.
RA Shields J. M., Yang V. W.
RT Identification of the DNA sequence that interacts with the gut-enriched Krueppel-like factor
RL Nucleic Acids Res. 26:796-802 (1998).
RN [4]; RE0006858.
RX PUBMED: 9428642.
RA Ton-That H., Kaestner K. H., Shields J. M., Mahatanankoon C. S., Yang V. W.
RT Expression of the gut-enriched Krueppel-like factor gene during development and intestinal tumorigenesis
RL FEBS Lett. 419:239-243 (1997).
RN [5]; RE0024733.
RX PUBMED: 9651398.
RA Zhang W., Shields J. M., Sogawa K., Fujii-Kuriyama Y., Yang V. W.
RT The gut-enriched Kruppel-like factor suppresses the activity of the CYP1A1 promoter in an Sp1-dependent fashion.
RL J. Biol. Chem. 273:17917-17925 (1998).
RN [6]; RE0063372.
RX PUBMED: 17908689.
RA Evans P. M., Zhang W., Chen X., Yang J., Bhakat K. K., Liu C.
RT Kruppel-like factor 4 is acetylated by p300 and regulates gene transcription via modulation of histone acetylation.
RL J. Biol. Chem. 282:33994-34002 (2007).
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