AC T15014
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ID T15014
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DT 21.08.2008 (created); pum.
DT 30.12.2014 (updated); ros.
CO Copyright (C), QIAGEN.
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FA SNA
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SY dJ710H13.1; SLUGH2; Sna; SNAH; SNAI1; Snail; snail homolog 1 (Drosophila).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G010170 SNAI1; HGNC: SNAI1.
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CL C0001; CH.
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SZ 264 AA; 29.1 kDa (cDNA) (calc.).
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SQ MPRSFLVRKPSDPNRKPNYSELQDSNPEFTFQQPYDQAHLLAAIPPPEILNPTASLPMLI
SQ WDSVLAPQAQPIAWASLRLQESPRVAELTSLSDEDSGKGSQPPSPPSPAPSSFSSTSVSS
SQ LEAEAYAAFPGLGQVPKQLAQLSEAKDLQARKAFNCKYCNKEYLSLGALKMHIRSHTLPC
SQ VCGTCGKAFSRPWLLQGHVRTHTGEKPFSCPHCSRAFADRSNLRAHLQTHSDVKKYQCQA
SQ CARTFSRMSLLHKHQESGCSGCPR
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SC Swiss-Prot#O95863
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FT 95 100 
beta-TrCP destruction motif [1].
FT 96 104 
GSK3beta phosphorylation motif [1].
FT 107 119 
GSK3beta phosphorylation motif [1].
FT 154 176 
PF00096; zf-C2H2.
FT 154 176 
SM00355; c2h2final6.
FT 154 177 
PS50157; ZINC_FINGER_C2H2_2.
FT 180 202 
PF00096; zf-C2H2.
FT 180 202 
SM00355; c2h2final6.
FT 180 207 
PS50157; ZINC_FINGER_C2H2_2.
FT 208 230 
PF00096; zf-C2H2.
FT 208 230 SM00355; c2h2final6.
FT 208 235 PS50157; ZINC_FINGER_C2H2_2.
FT 236 256 SM00355; c2h2final6.
FT 236 259 PF00096; zf-C2H2.
FT 236 263 PS50157; ZINC_FINGER_C2H2_2.
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IN T02872 beta-catenin; human, Homo sapiens.
IN T14513 beta-catenin; Mammalia.
IN T06570 Dnmt1; human, Homo sapiens.
IN T17209 ERK2; Mammalia.
IN T34686 G9A-isoform1; human, Homo sapiens.
IN T25617 sin3a; mouse, Mus musculus.
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MX M03566 V$SNA_Q4.
MX M07430 V$SNA_Q6.
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BS R37778.
BS R34757.
BS R39810.
BS R36727.
BS R35390.
BS R37828.
BS R37829.
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DR TRANSPATH: MO000133252.
DR EMBL: AF125377;
DR UniProtKB: O95863;
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RN [1]; RE0025033.
RX PUBMED: 15448698.
RA Zhou B. P., Deng J., Xia W., Xu J., Li Y. M., Gunduz M., Hung M. C.
RT Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition.
RL Nat. Cell Biol. 6:931-940 (2004).
RN [2]; RE0070143.
RX PUBMED: 19923321.
RA MacPherson M. R., Molina P., Souchelnytskyi S., Wernstedt C., Martin-Perez J., Portillo F., Cano A.
RT Phosphorylation of serine 11 and serine 92 as new positive regulators of human Snail1 function: potential involvement of casein kinase-2 and the cAMP-activated kinase protein kinase A.
RL Mol. Biol. Cell 21:244-253 (2010).
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