AC T25956
XX
ID T25956
XX
DT 12.12.2011 (created); yre.
DT 02.01.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA YAP-isoform2
XX
SY YAP; yAP1; YAP2; YAP65; yes-associated protein 1; Yes-associated protein 1, 65kDa; YKI.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G009620 YAP1; HGNC: yAP1.
XX
SZ 488 AA; 52.7 kDa (cDNA) (calc.).
XX
SQ MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD
SQ SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP
SQ QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA
SQ KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAM
SQ TQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS
SQ NQQQQMRLQQLQMEKERLRLKQQELLRQELALRSQLPTLEQDGGTQNPVSSPGMSQELRT
SQ MTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPS
SQ QQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLD
SQ KESFLTWL
XX
SC Swiss-Prot#P46937-2
XX
IN T02872 beta-catenin; human, Homo sapiens.
IN T14513 beta-catenin; Mammalia.
IN T00806 TEF-1; human, Homo sapiens.
IN T10484 TEF-3-isoform1; human, Homo sapiens.
IN T04951 TEF-3; human, Homo sapiens.
IN T20147 TEF-4; human, Homo sapiens.
IN T04952 TEF-5; human, Homo sapiens.
IN T10474 TEF-5; Mammalia.
XX
DR TRANSPATH: MO000198779.
DR UniProtKB: P46937-2;
XX
RN [1]; RE0071968.
RX PUBMED: 21205866.
RA Zhao B., Li L., Lu Q., Wang L. H., Liu C. Y., Lei Q., Guan K. L.
RT Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.
RL Genes Dev. 25:51-63 (2011).
RN [2]; RE0071974.
RX PUBMED: 21909427.
RA Wang P., Bai Y., Song B., Wang Y., Liu D., Lai Y., Bi X., Yuan Z.
RT PP1A-mediated dephosphorylation positively regulates YAP2 activity.
RL PLoS ONE 6:e24288 (2011).
RN [3]; RE0072017.
RX PUBMED: 20048001.
RA Zhao B., Li L., Tumaneng K., Wang C. Y., Guan K. L.
RT A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).
RL Genes Dev. 24:72-85 (2010).
XX
//