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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T25956 XX ID T25956 XX DT 12.12.2011 (created); yre. DT 02.01.2014 (updated); yre. CO Copyright (C), QIAGEN. XX FA YAP-isoform2 XX SY YAP; yAP1; YAP2; YAP65; yes-associated protein 1; Yes-associated protein 1, 65kDa; YKI. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G009620 YAP1; HGNC: yAP1. XX SZ 488 AA; 52.7 kDa (cDNA) (calc.). XX SQ MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGD SQ SETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTP SQ QHVRAHSSPASLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMA SQ KTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAM SQ TQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNS SQ NQQQQMRLQQLQMEKERLRLKQQELLRQELALRSQLPTLEQDGGTQNPVSSPGMSQELRT SQ MTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPS SQ QQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLD SQ KESFLTWL XX SC Swiss-Prot#P46937-2 XX IN T02872 beta-catenin; human, Homo sapiens. IN T14513 beta-catenin; Mammalia. IN T00806 TEF-1; human, Homo sapiens. IN T10484 TEF-3-isoform1; human, Homo sapiens. IN T04951 TEF-3; human, Homo sapiens. IN T20147 TEF-4; human, Homo sapiens. IN T04952 TEF-5; human, Homo sapiens. IN T10474 TEF-5; Mammalia. XX DR TRANSPATH: MO000198779. DR UniProtKB: P46937-2; XX RN [1]; RE0071968. RX PUBMED: 21205866. RA Zhao B., Li L., Lu Q., Wang L. H., Liu C. Y., Lei Q., Guan K. L. RT Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. RL Genes Dev. 25:51-63 (2011). RN [2]; RE0071974. RX PUBMED: 21909427. RA Wang P., Bai Y., Song B., Wang Y., Liu D., Lai Y., Bi X., Yuan Z. RT PP1A-mediated dephosphorylation positively regulates YAP2 activity. RL PLoS ONE 6:e24288 (2011). RN [3]; RE0072017. RX PUBMED: 20048001. RA Zhao B., Li L., Tumaneng K., Wang C. Y., Guan K. L. RT A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). RL Genes Dev. 24:72-85 (2010). XX //