AC T08703
XX
ID T08703
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DT 16.03.2006 (created); din.
DT 07.06.2012 (updated); pos.
CO Copyright (C), QIAGEN.
XX
FA Ku80
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SY 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase II, 80 kDa subunit; CTC box binding factor 85 kDa subunit; CTC85; CTCBF; DNA-repair protein XRCC5; G22P2; KU80; KU86; NF IV; nuclear factor IV; thyroid-lupus autoantigen; TLAA; XRCC5.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G014446 XRCC5; HGNC: XRCC5.
XX
SZ 732 AA; 82.7 kDa (cDNA) (calc.).
XX
SQ MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG
SQ TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH
SQ ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD
SQ GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI
SQ ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD
SQ DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ
SQ VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV
SQ YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT
SQ KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI
SQ EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV
SQ LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK
SQ ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE
SQ EGGDVDDLLDMI
XX
SC translated from EMBL #J04977
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FT 7 249 
SM00327; VWA_4.
FT 9 244 
PF03731; Ku70/Ku80 N-terminal alpha/beta domain.
FT 75 457 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 251 460 
PF02735; Ku70/Ku80 beta-barrel domain.
FT 302 441 
SM00559; Ku78.
FT 475 571 
PF03730; Ku70/Ku80 C-terminal arm.
XX
IN T05110 Ku70; human, Homo sapiens.
IN T22463 SNF2H; human, Homo sapiens.
XX
DR TRANSPATH: MO000079248.
DR EMBL: J04977; HSKUANT.
DR EMBL: M30938; HSKUP.
DR EMBL: X57500; HSNFIV.
DR UniProtKB: P13010; KU86_HUMAN.
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RN [1]; RE0044046.
RX PUBMED: 12171929.
RA Ohta S., Shiomi Y., Sugimoto K., Obuse C., Tsurimoto T.
RT A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein
RL J. Biol. Chem. 277:40362-7 (2002).
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