AC T08893
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ID T08893
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DT 08.05.2006 (created); man.
DT 25.03.2010 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA hdac2
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SY HD2; histone deacetylase 2; reduced potassium dependency 3; RPD3; YY1 transcription factor-binding protein.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006194 Hdac2.
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SZ 488 AA; 55.3 kDa (cDNA) (calc.).
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SQ MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKA
SQ TAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVA
SQ GAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHH
SQ GDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQ
SQ IFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVAKTFNLPLLMLG
SQ GGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYM
SQ EKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEE
SQ FSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDPKGA
SQ KSEQLSNP
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SC translated from EMBL #U31758
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FT 11 322 
PF00850; Histone deacetylase domain.
FT 32 391 
PF00478; IMP dehydrogenase / GMP reductase domai.
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IN T17631 HDAC1; mouse, Mus musculus.
IN T06148 p/CAF; human, Homo sapiens.
IN T10184 T3R-alpha1; Mammalia.
IN T00851 T3R-beta1; human, Homo sapiens.
IN T22092 T3R-beta2; Mammalia.
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DR TRANSPATH: MO000081078.
DR UniProtKB: P70288; HDA2_MOUSE.
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RN [1]; RE0028350.
RX PUBMED: 11302704.
RA Taplick J., Kurtev V., Kroboth K., Posch M., Lechner T., Seiser C.
RT Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1.
RL J. Mol. Biol. 308:27-38 (2001).
RN [2]; RE0047707.
RX PUBMED: 10508171.
RA Sasaki S., Lesoon-Wood L. A., Dey A., Kuwata T., Weintraub B. D., Humphrey G., Yang W. M., Seto E., Yen P. M., Howard B. H., Ozato K.
RT Ligand-induced recruitment of a histone deacetylase in the negative-feedback regulation of the thyrotropin beta gene.
RL EMBO J. 18:5389-5398 (1999).
RN [3]; RE0048072.
RX PUBMED: 12529406.
RA Yamagoe S., Kanno T., Kanno Y., Sasaki S., Siegel R. M., Lenardo M. J., Humphrey G., Wang Y., Nakatani Y., Howard B. H., Ozato K.
RT Interaction of histone acetylases and deacetylases in vivo.
RL Mol. Cell. Biol. 23:1025-1033 (2003).
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