AC T08930
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ID T08930
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DT 16.05.2006 (created); jag.
DT 10.06.2009 (updated); mka.
CO Copyright (C), QIAGEN.
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FA RXR-alpha
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SY NR2B1; retinoid X receptor alpha.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G008908 Rxra.
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CL C0002; CC (rec).
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SZ 467 AA; 51.3 kDa (cDNA) (calc.).
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SQ MDTKHFLPLDFSTQVNSSSLSSPTGRGSMAAPSLHPSLGPGLGSPLGSPGQLHSPISTLS
SQ SPINGMGPPFSVISSPMGPHSMSVPTTPTLGFETGSPQLNSPMNPVSSSEDIKPPLGLNG
SQ VLKVPAHPSGNMSSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNK
SQ DCLIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVEKI
SQ LEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD
SQ DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVS
SQ KMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRF
SQ AKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQTT
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SC translated from EMBL #L06482
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FT 71 464 PF00478; IMP dehydrogenase / GMP reductase domai.
FT 137 208 SM00399; c4gold.
FT 137 212 PS51030; NUCLEAR_REC_DBD_2.
FT 138 213 PF00105; Zinc finger, C4 type (two domains).
FT 275 434 SM00430; holi.
FT 278 459 PF00104; Ligand-binding domain of nuclear hormon.
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IN T25634 ASC-2; mouse, Mus musculus.
IN T05329 PPARgamma; rat, Rattus norvegicus.
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MX M00966 V$DR3_Q4.
MX M00965 V$DR4_Q2.
MX M07280 V$NR1NR2_Q3.
MX M00518 V$PPARA_02.
MX M00963 V$T3R_Q6.
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BS R09934.
BS R09966.
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DR TRANSPATH: MO000081484.
DR EMBL: L06482;
DR UniProtKB: Q05343;
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RN [1]; RE0000789.
RX PUBMED: 1312497.
RA Mangelsdorf D. J., Borgmeyer U., Heyman R. A., Zhou J. Y., Ong E. S., Oro A. E., Kakizuka A., Evans R. M.
RT Characterization of three RXR genes that mediate the action of 9-cis retinoic acid
RL Genes Dev. 6:329-344 (1992).
RN [2]; RE0023349.
RX PUBMED: 10334992.
RA Makishima M., Okamoto A. Y., Repa J. J., Tu H., Learned R. M., Luk A., Hull M. V., Lustig K. D., Mangelsdorf D. J., Shan B.
RT Identification of a nuclear receptor for bile acids.
RL Science 284:1362-1365 (1999).
RN [3]; RE0050597.
RX PUBMED: 10681503.
RA Caira F., Antonson P., Pelto-Huikko M., Treuter E., Gustafsson J. A.
RT Cloning and characterization of RAP250, a novel nuclear receptor coactivator.
RL J. Biol. Chem. 275:5308-5317 (2000).
RN [4]; RE0050623.
RX PUBMED: 9626662.
RA Treuter E., Albrektsen T., Johansson L., Leers J., Gustafsson J. A.
RT A regulatory role for RIP140 in nuclear receptor activation.
RL Mol. Endocrinol. 12:864-881 (1998).
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