AC T09021
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ID T09021
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DT 07.06.2006 (created); jag.
DT 19.03.2008 (updated); pum.
CO Copyright (C), QIAGEN.
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FA Sin3B-isoform1
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SY Histone deacetylase complex subunit Sin3b; Paired amphipathic helix protein Sin3b; Sin3b; Transcriptional corepressor Sin3b; transcriptional regulator, SIN3B (yeast).
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G013864 Sin3b.
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SZ 954 AA; 109.4 kDa (cDNA) (calc.).
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SQ MAHAGSGGSAGRGFGGSRWGRSGSGGHEKLPVHVEDALTYLDQVKIRFGSDPATYNGFLE
SQ IMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLSSQ
SQ DNSHSHGDCGEDFKQMSYKEDRGQVPLESDSVEFNNAISYVNKIKTRFLDHPEIYRSFLE
SQ ILHTYQKEQLHTKGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLPEAKRSLFTGNGS
SQ CEMNSGQKNEEKSLEHNKKRSRPSLLRPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFS
SQ FFDKVRRVLKSQEVYENFLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVK
SQ ELSFAPPMSDRSGDGISREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKEVLNDTWV
SQ SFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATIRVLESVQKKLSRMAPE
SQ DQEKLRLDDCLGGTSEVIQRRAIHRIYGDKAPEVIESLKRNPATAVPVVLKRLKAKEEEW
SQ REAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLLNEIESVYDEHQEQHSE
SQ GRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQGTIRQLLHRFLPSLFFS
SQ QQCPGTSDDSADERDRDRDSAEPERRRPTDEKPPADASPEPPKVLDDVYSLFFANNNWYF
SQ FLRLHQTLCARLLKIYRQAQKQLLEHRREQEREQLLCEGRREKAADPAMELRLKQPSEVE
SQ LEEYYPAFLDMVRSLLEGSIDPTQYEDTLREMFTIHAYIGFTMDKLVQNIARQLHHLVSD
SQ DVCLKVVELYLNEQQRGAAGGNLSSRCVRAARETSYQWKAERCMADENCFKVMFLQRRGQ
SQ VIMTIELLDTEEAQTEDPVEVQHLARYVEQYVGSEGASSSSTEGFLLKPVFLQR
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SC SPTREMBL #Q62141
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FT 52 98 
PF02671; Paired amphipathic helix repeat.
FT 172 228 
PF02671; Paired amphipathic helix repeat.
FT 312 358 
PF02671; Paired amphipathic helix repeat.
FT 449 944 
PF00478; IMP dehydrogenase / GMP reductase domain.
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IN T09020 Mad4; mouse, Mus musculus.
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DR TRANSPATH: MO000082624.
DR EMBL: L38622;
DR UniProtKB: Q62141-1;
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RN [1]; RE0006786.
RX PUBMED: 8521822.
RA Hurlin P. J., Queva C., Koskinen P. J., Steingrimsson E., Ayer D. E., Copeland N. G., Jenkins N. A., Eisenman R. N.
RT Mad3 and Mad4: novel Max-interacting transcriptional repressors that suppress c-myc dependent transformation and are expressed during neural and epidermal differentiation
RL EMBO J. 14:5646-5659 (1995).
RN [2]; RE0006789.
RX PUBMED: 7889570.
RA Ayer D. E., Lawrence Q. A., Eisenman R. N.
RT Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3
RL Cell 80:767-776 (1995).
RN [3]; RE0038190.
RX PUBMED: 11909966.
RA Alland L., David G., Shen-Li H., Potes J., Muhle R., Lee H. C., Hou H. Jr, Chen K., DePinho R. A.
RT Identification of mammalian Sds3 as an integral component of the Sin3/histone deacetylase corepressor complex
RL Mol. Cell. Biol. 22:2743-50 (2002).
RN [4]; RE0047858.
RX PUBMED: 12198164.
RA Vietor I., Vadivelu S. K., Wick N., Hoffman R., Cotten M., Seiser C., Fialka I., Wunderlich W., Haase A., Korinkova G., Brosch G., Huber L. A.
RT TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells.
RL EMBO J. 21:4621-4631 (2002).
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