AC T09169
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ID T09169
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DT 01.08.2006 (created); ran.
DT 13.03.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA mtTFA-isoform1
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SY mitochondrial transcription factor A; mtTF1; mtTFA; TCF6; TCF6L2; transcription factor 6-like 2; transcription factor A, mitochondrial.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004971 TFAM; HGNC: TFAM.
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CL C0015; HMG.
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SZ 246 AA; 29.1 kDa (cDNA) (calc.).
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SQ MAFLRSMWGVLSALGRSGAELCTGCGSRLRSPFSFVYLPRWFSSVLASCPKKPVSSYLRF
SQ SKEQLPIFKAQNPDAKTTELIRRIAQRWRELPDSKKKIYQDAYRAEWQVYKEEISRFKEQ
SQ LTPSQIMSLEKEIMDKHLKRKAMTKKKELTLLGKPKRPRSAYNVYVAERFQEAKGDSPQE
SQ KLKTVKENWKNLSDSEKELYIQHAKEDETRYHNEMKSWEEQMIEVGRKDLLRRTIKKQRK
SQ YGAEEC
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SC Swiss-Prot#Q00059
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FT 49 119 
SM00398; hmgende2.
FT 50 118 
PF00505; HMG (high mobility group) box.
FT 50 118 
PS50118; HMG_BOX_2.
FT 154 220 
SM00398; hmgende2.
FT 155 219 
PF00505; HMG (high mobility group) box.
FT 155 219 
PS50118; HMG_BOX_2.
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IN T08321 p53-isoform1; human, Homo sapiens.
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DR TRANSPATH: MO000084022.
DR EMBL: M62810;
DR EMBL: X64269;
DR UniProtKB: Q00059;
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RN [1]; RE0002651.
RX PUBMED: 2035027.
RA Parisi M. A., Clayton D. A.
RT Similarity of human mitochondrial transcription factor 1 to high mobility group proteins
RL Science 252:965-969 (1991).
RN [2]; RE0048017.
RX PUBMED: 12839966.
RA Yoshida Y., Izumi H., Torigoe T., Ishiguchi H., Itoh H., Kang D., Kohno K.
RT P53 physically interacts with mitochondrial transcription factor A and differentially regulates binding to damaged DNA.
RL Cancer Res. 63:3729-3734 (2003).
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