AC T09221
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ID T09221
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DT 16.08.2006 (created); din.
DT 30.07.2009 (updated); jag.
CO Copyright (C), QIAGEN.
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FA rax
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SY E130303K03Rik; ey-1; ey1; Mrx; RAX; retina and anterior neural fold homeobox; retina and anterior neural fold homeobox protein; Rx.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006637 Rax.
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CL C0006; homeo.
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SZ 342 AA; 36.3 kDa (cDNA) (calc.).
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SQ MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKEDGILDTFPAERSSRSS
SQ KERDPRLGAQPACPKAPAGGSESSPPAAPGFVPEYEATRPCYPKEQGEARPSPGLSVGPA
SQ AGDSKLSEEEPPKKKHRRNRTTFTTYQLHELERAFEKSHYPDVYSREELAGKVNLPEVRV
SQ QVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSSALAPLGTGPGSGSGPPGSALP
SQ LEPWLGPPLPGGGATALQSLPGFGPPGQGLPASYTPPPPFLNSAPLGPGLQQLGPPPAYP
SQ CAPAFGDKFSLEEAYPRNSSIAALRLKAKEHIQAIGKPWQAL
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SC translated from EMBL #U73177
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FT 33 40 
conserved octapeptide [2].
FT 134 194 
PS50071; HOMEOBOX_2.
FT 136 192 
PS50552; PAX.
FT 136 198 
SM00389; HOX_1.
FT 137 193 
PF00046; Homeobox domain.
FT 314 334 
PF03826; OAR domain.
FT 319 332 
OAR domain [2].
FT 319 332 
PS50803; OAR.
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IN T00682 Pax-6; zebra fish, Brachydanio rerio.
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MX M00623 V$CRX_Q4.
MX M01389 V$RAX_01.
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DR TRANSPATH: MO000085054.
DR EMBL: U73177;
DR UniProtKB: O35602;
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RN [1]; RE0006132.
RX PUBMED: 9177348.
RA Mathers P.H., Ginsberg A., Mahon K. A., Jamrich M.
RT The Rx homeobox gene is essential for vertebrate eye development
RL Nature 387:603-607 (1997).
RN [2]; RE0014693.
RX PUBMED: 9096350.
RA Furukawa T., Kozak C. A., Cepko C. L.
RT rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina
RL Proc. Natl. Acad. Sci. USA 94:3088-3093 (1997).
RN [3]; RE0017886.
RX PUBMED: 10625658.
RA Kimura A., Singh D., Wawrousek E. F., Kikuchi M., Nakamura M., Shinohara T.
RT Both PCE-1/RX and OTX/CRX interactions are necessary for photoreceptor-specific gene expression.
RL J. Biol. Chem. 275:1152-1160 (2000).
RN [4]; RE0047970.
RX PUBMED: 11069920.
RA Mikkola I., Bruun J. A., Holm T., Johansen T.
RT Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins.
RL J. Biol. Chem. 276:4109-4118 (2001).
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