TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T09234 XX ID T09234 XX DT 16.08.2006 (created); din. CO Copyright (C), QIAGEN. XX FA HOXB1-isoform1 XX SY homeo box B1; Hox-2.9; HOX2I; HOXB1. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004684 HOXB1; HGNC: HOXB1. XX CL C0006; homeo. XX SZ 301 AA; 32.1 kDa (cDNA) (calc.). XX SQ MDYNRMNSFLEYPLCNRGPSAYSAHSAPTSFPPSSAQAVDSYASEGRYGGGLSSPAFQQN SQ SGYPAQQPPSTLGVPFPSSAPSGYAPAACSPSYGPSQYYPLGQSEGDGGYFHPSSYGAQL SQ GGLSDGYGAGGAGPGPYPPQHPPYGNEQTASFAPAYADLLSEDKETPCPSEPNTPTARTF SQ DWMKVKRNPPKTAKVSEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATL SQ ELNETQVKIWFQNRRMKQKKREREGGRVPPAPPGCPKEAAGDASDQSTCTSPEASPSSVT SQ S XX SC Swiss-Prot#P14653 XX FT 1 155 transactivation domain [10]. FT 201 261 PS50071; HOMEOBOX_2. FT 203 265 SM00389; HOX_1. FT 204 260 PF00046; Homeobox domain. XX IN T00682 Pax-6; zebra fish, Brachydanio rerio. XX BS R15357. BS R14719. BS R09699. BS R12755. BS R32602. BS R32606. XX DR TRANSPATH: MO000085084. DR EMBL: X16666; DR UniProtKB: P14653; XX RN [1]; RE0003886. RX PUBMED: 2576652. RA Boncinelli E., Acampora D., Pannese M., D'Esposito M., Somma R., Gaudino G., Stornaiuolo A., Cafiero M., Faiella A., Simeone A. RT Organization of human class I homeobox genes RL Genome 31:745-756 (1989). RN [2]; RE0003895. RX PUBMED: 2574852. RA Acampora D., D'Esposito M., Faiella A., Pannese M., Migliaccio E., Morelli F., Stornaiuolo A., Nigro V., Simeone A., Boncinelli E. RT The human HOX gene family RL Nucleic Acids Res. 17:10385-10402 (1989). RN [3]; RE0003909. RX PUBMED: 7831296. RA Ogura T., Evans R. M. RT A retinoic acid-triggered cascade of HOXB1 gene activation RL Proc. Natl. Acad. Sci. USA 92:387-391 (1995). RN [4]; RE0003910. RX PUBMED: 7831297. RA Ogura T., Evans R. M. RT Evidence for two distinct retinoic acid response pathways for HOXB1 gene regulation RL Proc. Natl. Acad. Sci. USA 92:392-396 (1995). RN [5]; RE0003920. RX PUBMED: 1712489. RA Magli M. C., Barba P., Celetti A., de Vita G., Cillo C., Boncinelli E. RT Coordinate regulation of HOX genes in human hematopoietic cells RL Proc. Natl. Acad. Sci. USA 88:6348-6352 (1991). RN [6]; RE0003921. RX PUBMED: 1975088. RA Simeone A., Acampora D., Arcioni L., Andrews P. W., Boncinelli E., Mavilio F. RT Sequential activation of HOX2 homeobox genes by retinoic acid in human embryonal carcinoma cells RL Nature 346:763-766 (1990). RN [7]; RE0003924. RX PUBMED: 1360433. RA Safaei R., Prochazka V., Detmer K., Boncinelli E., Lawrence H. J., Largman C. RT Modulation of HOX2 gene expression following differentiation of neural cell lines RL Differentiation 5:39-47 (1992). RN [8]; RE0003925. RX PUBMED: 7911974. RA Care A., Testa U., Bassani A., Tritarelli E., Montesoro E., Samoggia P., Cianetti L., Peschle C. RT Coordinate expression and proliferative role of HOXB genes in activated adult T lymphocytes RL Mol. Cell. Biol. 14:4872-4877 (1994). RN [9]; RE0003926. RX PUBMED: 7911240. RA Faiella A., Zappavigna V., Mavilio F., Boncinelli E. RT Inhibition of retinoic acid-induced activation of 3' human HOXB genes by antisense oligonucleotides affects sequential activation of genes located upstream in the four HOX clusters RL Proc. Natl. Acad. Sci. USA 91:5335-5339 (1994). RN [10]; RE0005973. RX PUBMED: 9218805. RA Rocco di G., Mavilio F., Zappavigna V. RT Functional dissection of a transcripitonally active, target-specific Hox-Pbx complex RL EMBO J. 16:3644-3654 (1997). RN [11]; RE0015483. RX PUBMED: 11091361. RA Ingram J. L., Stodgell C. J., Hyman S. L., Figlewicz D. A., Weitkamp L. R., Rodier P. M. RT Discovery of allelic variants of HOXA1 and HOXB1: Genetic susceptibility to autism spectrum disorders RL Teratology 62:393-405 (2000). RN [12]; RE0015500. RX PUBMED: 9482740. RA Berthelsen J., Zappavigna V., Ferretti E., Mavilio F., Blasi F. RT The novel homeoprotein Prep1 modulates Pbx-Hox protein cooperativity RL EMBO J. 17:1434-1445 (1998). RN [13]; RE0047970. RX PUBMED: 11069920. RA Mikkola I., Bruun J. A., Holm T., Johansen T. RT Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins. RL J. Biol. Chem. 276:4109-4118 (2001). XX //