AC T09359
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ID T09359
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DT 05.10.2006 (created); tgo.
CO Copyright (C), QIAGEN.
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FA GATA-4-isoform1
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SY GATA-box binding factor 4.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004007 GATA4; HGNC: GATA4.
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CL C0003; CC (g).
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SZ 442 AA; 44.6 kDa (cDNA) (calc.).
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SQ MYQSLAMAANHGPPPGAYQAGGPGPFMHGAGAASSPVYLPTPRVPSSVLGLSYLQGGGAG
SQ SASGGPSGGSPGGAASGAGPGTQQGSPGWSQAGATGAAYTPPPVSPRFSFPGTTGSLAAA
SQ AAAAAAREAAAYSSGGGAAGAGLAGREQYGRAGFAGSYSSPYPAYMADVGASWAAAAAAS
SQ AGPFDSPVLHSLPGRANPAARHPNLDMFDDFSEGRECVNCGAMSTPLWRRDGTGHYLCNA
SQ CGLYHKMNGINRPLIKPQRRLSASRRVGLSCANCQTTTTTLWRRNAEGEPVCNACGLYMK
SQ LHGVPRPLAMRKEGIQTRKRKPKNLNKSKTPAAPSGSESLPPASGASSNSSNATTSSSEE
SQ MRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQT
SQ SSKQDSWNSLVLADSHGDIITA
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SC Swiss-Prot#P43694
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FT 1 208 PF05349; GATA-type transcription activator, N-termina.
FT 211 261 SM00401; ZnF_GATA.
FT 211 265 PS50114; GATA_ZN_FINGER_2.
FT 217 251 PF00320; GATA zinc finger.
FT 265 315 SM00401; ZnF_GATA.
FT 265 318 PS50114; GATA_ZN_FINGER_2.
FT 271 305 PF00320; GATA zinc finger.
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IN T00373 HNF-4alpha1; human, Homo sapiens.
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MX M00632 V$GATA4_Q3.
MX M03549 V$GATA4_Q5_01.
MX M00789 V$GATA_Q6.
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BS R63188.
BS R14541.
BS R61607.
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DR TRANSPATH: MO000088163.
DR EMBL: L34357;
DR UniProtKB: P43694;
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RN [1]; RE0013539.
RX PUBMED: 9566909.
RA Gao X., Sedgwick T., Shi Y.-B., Evans T.
RT Distinct functions are implicated for the GATA-4, -5, and -6 transcription factors in the regulation of intestine epithelial cell differentiation.
RL Mol. Cell. Biol. 18:2901-2911 (1998).
RN [2]; RE0013561.
RX PUBMED: 7721094.
RA Huang W. Y., Cukerman E., Liew C. C.
RT Identification of a GATA motif in the cardiac alpha-myosin heavy-chain-encoding gene and isolation of a human GATA-4 cDNA.
RL Gene 155:219-223 (1995).
RN [3]; RE0025189.
RX PUBMED: 10075728.
RA Shiojima I., Komuro I., Oka T., Hiroi Y., Mizuno T., Takimoto E., Monzen K., Aikawa R., Akazawa H., Yamazaki T., Kudoh S., Yazaki Y.
RT Context-dependent transcriptional cooperation mediated by cardiac transcription factors Csx/Nkx-2.5 and GATA-4.
RL J. Biol. Chem. 274:8231-8239 (1999).
RN [4]; RE0055387.
RX PUBMED: 17403900.
RA Sumi K., Tanaka T., Uchida A., Magoori K., Urashima Y., Ohashi R., Ohguchi H., Okamura M., Kudo H., Daigo K., Maejima T., Kojima N., Sakakibara I., Jiang S., Hasegawa G., Kim I., Osborne T. F., Naito M., Gonzalez F. J., Hamakubo T., Kodama T., Sakai J.
RT Cooperative interaction between hepatocyte nuclear factor 4 alpha and GATA transcription factors regulates ATP-binding cassette sterol transporters ABCG5 and ABCG8.
RL Mol. Cell. Biol. 27:4248-4260 (2007).
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