AC T09428
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ID T09428
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DT 10.10.2006 (created); sri.
DT 15.06.2012 (updated); jtr.
CO Copyright (C), QIAGEN.
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FA COUP-TF1
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SY chicken ovalbumin upstream promoter transcription factor; COUP-TF; COUP-TF1; COUP-TFI; COUPTFA; EAR3; ERBAL3; NR2F1; nuclear receptor subfamily 2, group F, member 1; SVP44; TCFCOUP1.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G014472 Nr2f1.
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CL C0002; CC (rec).
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SZ 422 AA; 46.1 kDa (cDNA) (calc.).
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SQ MAMVVSSWRDPQDDVAGGNPGGPNPAAQAARGGGGGAGEQQQAGSGAPHTPQTPGQPGAP
SQ ATPGTQGDKGQGPPGSGQSQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYT
SQ CRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPNPGQYALTNGDPLNG
SQ HCYLSGYISLLLRAEPYPTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFP
SQ DLQITDQVSLLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRI
SQ FQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYP
SQ NQPSRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMSIQ
SQ CS
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SC translated from EMBL #U07625
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FT 82 153 
SM00399; c4gold.
FT 82 157 
PS51030; NUCLEAR_REC_DBD_2.
FT 83 158 
PF00105; Zinc finger, C4 type (two domains).
FT 93 364 
PF00478; IMP dehydrogenase / GMP reductase domai.
FT 220 380 
SM00430; holi.
FT 223 405 
PF00104; Ligand-binding domain of nuclear hormon.
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IN T27831 BCL-11A; mouse, Mus musculus.
IN T04689 SMRT; human, Homo sapiens.
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MX M00765 V$COUPDR1_Q6.
MX M03542 V$COUPTF1_Q6_01.
MX M01036 V$COUPTF_Q6.
MX M00158 V$COUP_01.
MX M00762 V$DR1_Q3.
MX M00965 V$DR4_Q2.
MX M00967 V$HNF4_Q6.
MX M07280 V$NR1NR2_Q3.
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BS R16112.
BS R39145.
BS R16109.
BS R36199.
BS R16929.
BS R35917.
BS R12982.
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DR TRANSPATH: MO000088718.
DR EMBL: U07625; U07625.
DR UniProtKB: Q60632; COT1_MOUSE.
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RN [1]; RE0001755.
RX PUBMED: 1584212.
RA Liu Y., Teng C. T.
RT Estrogen response module of the mouse lactoferrin gene contains overlapping chicken ovalbumin up-stream promoter transcription factor and estrogen receptor-binding elements
RL Mol. Endocrinol. 6:355-364 (1992).
RN [2]; RE0024770.
RX PUBMED: 7947324.
RA Jonk L. J., de Jonge M. E., Pals C. E., Wissink S., Vervaart J. M., Schoorlemmer J., Kruijer W.
RT Cloning and expression during development of three murine members of the COUP family of nuclear orphan receptors.
RL Mech. Dev. 47:81-97 (1994).
RN [3]; RE0025190.
RX PUBMED: 11106640.
RA Guo L., Lynch J., Nakamura K., Fliegel L., Kasahara H., Izumo S., Komuro I., Agellon L. B., Michalak M.
RT COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development.
RL J. Biol. Chem. 276:2797-2801 (2001).
RN [4]; RE0048421.
RX PUBMED: 16219912.
RA Johnson D. R., Li C. W., Chen L. Y., Ghosh J. C., Chen J. D.
RT Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT).
RL Mol. Pharmacol. 69:99-108 (2006).
RN [5]; RE0052267.
RX PUBMED: 10744719.
RA Avram D., Fields A., Pretty On Top K., Nevrivy D. J., Ishmael J. E., Leid M.
RT Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.
RL J. Biol. Chem. 275:10315-10322 (2000).
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