AC T09461
XX
ID T09461
XX
DT 11.10.2006 (created); tgo.
DT 24.04.2013 (updated); asv.
CO Copyright (C), QIAGEN.
XX
FA Smad4
XX
SY SMAD-4.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G006379 Smad4.
XX
CL C0041; SMAD.
XX
SZ 551 AA; 60.4 kDa (cDNA) (calc.).
XX
SQ MDNMSITNTPTSNDACLSIVHSLMCHRQGGESETFAKRAIESLVKKLKEKKDELDSLITA
SQ ITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKYCQYAFD
SQ LKCDSVCVNPYHYERVVSPGIDLSGLTLQSNAPSMLVKDEYVHDFEGQPSLPTEGHSIQT
SQ IQHPPSNRASTETYSAPALLAPAESNATSTTNFPNIPVASTSQPASILAGSHSEGLLQIA
SQ SGPQPGQQQNGFTAQPSTYHHNSTTTWTGSRTAPYTPNLPHHQNGHLQHHPRMPPHPGHY
SQ WPVHNELAFQPPISNHPAPEYWCSIAYFEMDVQVGETFKVPSSCPVVTVDGYVDPSGGDR
SQ FCLGQLSNVHRTEAIERARLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRA
SQ PGDAVHKIYPSAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPA
SQ ISLSAAAGIGVDDLRRLCILRMSFVKGWGPDYPRQSIKETPCWIEIHLHRALQLLDEVLH
SQ TMPIADPQPLD
XX
SC translated from EMBL #U79748
XX
FT 18 142 
PS51075; MH1.
FT 31 140 
SM00523; dwAneu5.
FT 33 137 
PF03165; MH1 domain.
FT 192 518 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 316 531 
PF03166; MH2 domain.
FT 320 529 
SM00524; DWB.
FT 322 551 
PS51076; MH2.
XX
IN T09086 Smad2; mouse, Mus musculus.
XX
MX M07368 V$SMAD4_Q4.
MX M00733 V$SMAD4_Q6.
MX M01889 V$SMAD4_Q6_01.
MX M08897 V$SMAD_Q4.
MX M00792 V$SMAD_Q6.
MX M00974 V$SMAD_Q6_01.
XX
BS R16509.
BS R16510.
BS R13582.
BS R31514.
BS R55729.
BS R37792.
XX
DR TRANSPATH: MO000088883.
DR TRANSCOMPEL: C00557.
DR TRANSCOMPEL: C00574.
DR EMBL: U79748;
DR UniProtKB: P97471;
XX
RN [1]; RE0016380.
RX PUBMED: 11074002.
RA Pierreux C. E., Nicolas F. J., Hill C. S.
RT Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.
RL Mol. Cell. Biol. 20:9041-9054 (2000).
RN [2]; RE0072535.
RX PUBMED: 18568018.
RA Varelas X., Sakuma R., Samavarchi-Tehrani P., Peerani R., Rao B. M., Dembowy J., Yaffe M. B., Zandstra P. W., Wrana J. L.
RT TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
RL Nat. Cell Biol. 10:837-848 (2008).
XX
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