AC T09522
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ID T09522
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DT 30.10.2006 (created); jul.
DT 22.01.2013 (updated); yre.
CO Copyright (C), QIAGEN.
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FA RelB
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SY I-Rel; IREL; RELB; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (avian).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004623 RELB; HGNC: RELB.
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CL C0020; Rel.
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SZ 579 AA; 62.1 kDa (cDNA) (calc.).
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SQ MLRSGPASGPSVPTGRAMPSRRVARPPAAPELGALGSPDLSSLSLAVSRSTDELEIIDEY
SQ IKENGFGLDGGQPGPGEGLPRLVSRGAASLSTVTLGPVAPPATPPPWGCPLGRLVSPAPG
SQ PGPQPHLVITEQPKQRGMRFRYECEGRSAGSILGESSTEASKTLPAIELRDCGGLREVEV
SQ TACLVWKDWPHRVHPHSLVGKDCTDGICRVRLRPHVSPRHSFNNLGIQCVRKKEIEAAIE
SQ RKIQLGIDPYNAGSLKNHQEVDMNVVRICFQASYRDQQGQMRRMDPVLSEPVYDKKSTNT
SQ SELRICRINKESGPCTGGEELYLLCDKVQKEDISVVFSRASWEGRADFSQADVHRQIAIV
SQ FKTPPYEDLEIVEPVTVNVFLQRLTDGVCSEPLPFTYLPRDHDSYGVDKKRKRGMPDVLG
SQ ELNSSDPHGIESKRRKKKPAILDHFLPNHGSGPFLPPSALLPDPDFFSGTVSLPGLEPPG
SQ GPDLLDDGFAYDPTAPTLFTMLDLLPPAPPHASAVVCSGGAGAVVGETPGPEPLTLDSYQ
SQ APGPGDGGTASLVGSNMFPNHYREAAFGGGLLSPGPEAT
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SC Swiss-Prot#Q01201
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FT 122 299 
PS50254; REL_2.
FT 127 295 
PF00554; Rel homology domain (RHD).
FT 302 398 
SM00429; iptmega2.
FT 303 398 
PF01833; IPT/TIG domain.
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IN T22508 dpf2-isoform1; human, Homo sapiens.
IN T17520 NF-kappaB1; Mammalia.
IN T23075 p100; Mammalia.
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DR TRANSPATH: MO000089782.
DR EMBL: M83221;
DR UniProtKB: Q01201;
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RN [1]; RE0004536.
RX PUBMED: 7925301.
RA Dobrzanski P., Ryseck R.-P., Bravo R.
RT Differential interactions of RelB-NF-kappaB complexes with IkappaBalpha determine pools of constitutive and inducible NF-kappaB activity
RL EMBO J. 13:4608-4616 (1994).
RN [2]; RE0004560.
RX PUBMED: 8441398.
RA Dobrzanski P., Ryseck R. P., Bravo R.
RT Both N- and C- terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif
RL Mol. Cell. Biol. 13:1572-1582 (1993).
RN [3]; RE0004564.
RX PUBMED: 1577270.
RA Ruben S. M., Klement J. F., Maher M., Coleman T. A., Chen C.-M., Rosen C. A.
RT I-Rel: a novel rel-related protein that inhibits NF-kappaB transcriptional activity
RL Genes Dev. 6:745-760 (1992).
RN [4]; RE0054072.
RX PUBMED: 11687592.
RA Solan N. J., Miyoshi H., Carmona E. M., Bren G. D., Paya C. V.
RT RelB cellular regulation and transcriptional activity are regulated by p100.
RL J. Biol. Chem. 277:1405-1418 (2002).
RN [5]; RE0070954.
RX PUBMED: 20460684.
RA Tando T., Ishizaka A., Watanabe H., Ito T., Iida S., Haraguchi T., Mizutani T., Izumi T., Isobe T., Akiyama T., Inoue J., Iba H.
RT Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway.
RL J. Biol. Chem. 285:21951-21960 (2010).
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