AC T10006
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ID T10006
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DT 11.12.2006 (created); kau.
DT 11.10.2010 (updated); jig.
CO Copyright (C), QIAGEN.
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FA Myf-5
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SY Myf-5.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003932 MYF5; HGNC: MYF5.
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CL C0010; bHLH.
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SZ 255 AA; 28.4 kDa (cDNA) (calc.).
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SQ MDVMDGCQFSPSEYFYDGSCIPSPEGEFGDEFVPRVAAFGAHKAELQGSDEDEHVRAPTG
SQ HHQAGHCLMWACKACKRKSTTMDRRKAATMRERRRLKKVNQAFETLKRCTTTNPNQRLPK
SQ VEILRNAIRYIESLQELLREQVENYYSLPGQSCSEPTSPTSNCSDGMPECNSPVWSRKSS
SQ TFDSIYCPDVSNVYATDKNSLSSLDCLSNIVDRITSSEQPGLPLQDLASLSPVASTDSQP
SQ RTPGASSSRLIYHVL
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SC Swiss-Prot#P13349
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FT 1 83 
PF01586; Myogenic Basic domain.
FT 1 88 
SM00520; BASIC.
FT 83 135 
PS50888; HLH.
FT 84 135 
PF00010; Helix-loop-helix DNA-binding domain.
FT 89 140 
SM00353; finulus.
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IN T00403 Id1; mouse, Mus musculus.
IN T10004 Id2; mouse, Mus musculus.
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MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M03880 V$MYF5_Q6.
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BS R02418.
BS R02419.
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DR TRANSPATH: MO000094579.
DR EMBL: X14894;
DR UniProtKB: P13349;
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RN [1]; RE0000475.
RX PUBMED: 2583111.
RA Braun T., Bober E., Buschhausen-Denker G., Kotz S., Grzeschik K., Arnold H. H.
RT Differential expression of myogenic determination genes in muscle cells: possible autoactivation by the Myf gene products
RL EMBO J. 8:3617-3625 (1989).
RN [2]; RE0000476.
RX PUBMED: 2721498.
RA Braun T., Buschhausen-Denker G., Bober E., Tannich E., Arnold H. H.
RT A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts
RL EMBO J. 8:701-709 (1989).
RN [3]; RE0001863.
RX PUBMED: 2385294.
RA Braun T., Winter B., Bober E., Arnold H. H.
RT Transcriptional activation domain of the muscle-specific gene-regulatory protein myf5
RL Nature 346:663-665 (1990).
RN [4]; RE0002108.
RX PUBMED: 1945842.
RA Braun T., Arnold H. H.
RT The four helix-loop-helix proteins Myf3-Myf6 exhibit similar hetero-dimerization and DNA binding properties
RL Nucleic Acids Res. 19:5645-5651 (1991).
RN [5]; RE0003234.
RX PUBMED: 8387507.
RA Winter B., Braun T., Arnold H. H.
RT cAMP-dependent protein kinase represses myogenic differentiation and the activity of the muscle-specific helix-loop-helix transcription factors Myf-5 and MyoD
RL J. Biol. Chem. 13:9869-9878 (1993).
RN [6]; RE0003260.
RX PUBMED: 1315706.
RA Braun T., Bober E., Arnold H. H.
RT Inhibition of muscle differentiation by the adenovirus E1a protein: Repression of the transcriptional activating function of the HLH protein Myf-5
RL Genes Dev. 6:888-902 (1992).
RN [7]; RE0003261.
RX PUBMED: 1582413.
RA Winter B., Braun T., Arnold H.-H.
RT Co-operativity of functional domains in the muscle-specific transcription factor Myf-5
RL EMBO J. 11:1843-1855 (1992).
RN [8]; RE0048980.
RX PUBMED: 9242638.
RA Langlands K., Yin X., Anand G., Prochownik E. V.
RT Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.
RL J. Biol. Chem. 272:19785-19793 (1997).
RN [9]; RE0067513.
RX PUBMED: 16980408.
RA Wu Z., Huang X., Feng Y., Handschin C., Feng Y., Gullicksen P. S., Bare O., Labow M., Spiegelman B., Stevenson S. C.
RT Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.
RL Proc. Natl. Acad. Sci. USA 103:14379-14384 (2006).
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