AC T10071
XX
ID T10071
XX
DT 04.01.2007 (created); tgo.
DT 17.12.2010 (updated); pro.
CO Copyright (C), QIAGEN.
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FA sp4
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SY HF-1b (rat); SP-4; SPR-1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003999 SP4; HGNC: SP4.
XX
CL C0001; CH.
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SZ 784 AA; 82.0 kDa (cDNA) (calc.).
XX
SQ MSDQKKEEEEEAAAAAAMATEGGKTSEPENNNKKPKTSGSQDSQPSPLALLAATCSKIGT
SQ PGENQATGQQQIIIDPSQGLVQLQNQPQQLELVTTQLAGNAWQLVASTPPASKENNVSQP
SQ ASSSSSSSSSNNGSASPTKTKSGNSSTPGQFQVIQVQNPSGSVQYQVIPQLQTVEGQQIQ
SQ INPTSSSSLQDLQGQIKLISAGNNQAILTAANRTASGNILAQNLANQTVPVQIRPGVSIP
SQ LQLQTLPGTQAQVVTTLPINIGGVTLALPVINNVAAGGGTGQVGQPAATADSGTSNGNQL
SQ VSTPTNTTTSASTMPESPSSSTTCTTTASTSLTSSDTLVSSADTGQYASTSASSSERTIE
SQ ESQTPAATESEAQSSSQLHANGMQNQQDQSNSLQQVQIVGQPILQQIQIQQPQQQIIQAI
SQ PPQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLTPSGQISWQTVQVQNIQSL
SQ SNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQLASVPNLQTVSVAN
SQ LGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIGAVSPDQLTQ
SQ VHLQQGQQTSDQEVQPGKRLRRVACSCPNCREGEGRGSNEPGKKKQHICHIEGCGKVYGK
SQ TSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSD
SQ HLSKHVKTHQNKKGGGTALAIVTSGELDSSVTEVLGSPRIVTVAAISQDSNPATPNVSTN
SQ MEEF
XX
SC Swiss-Prot#Q02446
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FT 172 615 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 647 671 
PF00096; zf-C2H2.
FT 647 671 
SM00355; c2h2final6.
FT 647 676 
PS50157; ZINC_FINGER_C2H2_2.
FT 677 701 
PF00096; zf-C2H2.
FT 677 701 
SM00355; c2h2final6.
FT 677 706 
PS50157; ZINC_FINGER_C2H2_2.
FT 707 729 
PF00096; zf-C2H2.
FT 707 729 
SM00355; c2h2final6.
FT 707 734 
PS50157; ZINC_FINGER_C2H2_2.
XX
IN T03489 Crx; cattle, Bos taurus.
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MX M01273 V$SP4_Q5.
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DR TRANSPATH: MO000095624.
DR EMBL: X68561; HSSPR1.
DR UniProtKB: Q02446; SP4_HUMAN.
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RN [1]; RE0006538.
RX PUBMED: 1454515.
RA Hagen G., Muller S., Beato M., Suske G.
RT Cloning by recognition site screening of two novel GT box binding proteins: a familiy of Sp1 related genes
RL Nucleic Acids Res. 20:5519-5525 (1992).
RN [2]; RE0006539.
RX PUBMED: 7759528.
RA Dennig J., Hagen G., Beato M., Suske G.
RT Members of the Sp transcription factor family control transcription from the uteroglobin promoter
RL J. Biol. Chem. 270:12737-12744 (1995).
RN [3]; RE0006654.
RX PUBMED: 7800480.
RA Majello B., de Luca P., Hagen G., Suske G., Lania L.
RT Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1
RL Nucleic Acids Res. 22:4914-4921 (1994).
RN [4]; RE0060035.
RX PUBMED: 15781457.
RA Lerner L. E., Peng G. H., Gribanova Y. E., Chen S., Farber D. B.
RT Sp4 is expressed in retinal neurons, activates transcription of photoreceptor-specific genes, and synergizes with Crx.
RL J. Biol. Chem. 280:20642-20650 (2005).
XX
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