AC T10281
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ID T10281
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DT 01.03.2007 (created); ask.
DT 15.04.2015 (updated); pro.
CO Copyright (C), QIAGEN.
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FA Gbx2
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SY gastrulation and brain specific homeobox protein 2; MMoxA; stimulated with RA 7; Stra7.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G002048 Gbx2.
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CL C0006; homeo.
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SZ 348 AA; 37.4 kDa (cDNA) (calc.).
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SQ MSAAFPPSLMMMQRPLGSSTAFSIDSLIGSPPQPSPGHFVYTGYPMFMPYRPVVLPPPPP
SQ PPPALPQAALQPALPPAHPHHQIPSLPTGFCSSLAQGMALTSTLMATLPGGFSASPQHQE
SQ AAAARKFAPQPLPGGGNFDKAEALQADAEDGKAFLAKEGSLLAFSAAEAVQASLVGAVRG
SQ QGKDESKVEDDPKGKEESFSLESDVDYSSDDNLPGQTAHKEEDPGHALEETPQSGGAAGS
SQ TTSTGKNRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRA
SQ KWKRVKAGNANSKTGEPSRNPKIVVPIPVHVSRFAIRSQHQQLEQARP
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SC translated from EMBL #Z48800
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FT 46 348 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 245 305 
PS50071; HOMEOBOX_2.
FT 247 309 
SM00389; HOX_1.
FT 248 304 
PF00046; Homeobox domain.
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IN T09219 Grg4; mouse, Mus musculus.
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MX M01382 V$GBX2_01.
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BS R40794.
BS R40793.
BS R40792.
BS R40790.
BS R40791.
BS R67208.
BS R20636.
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DR TRANSPATH: MO000101721.
DR EMBL: U74300;
DR EMBL: Z48800;
DR UniProtKB: P48031;
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RN [1]; RE0014515.
RX PUBMED: 1720547.
RA Murtha M. T., Leckman J. F., Ruddle F. H.
RT Detection of homeobox genes in development and evolution
RL Proc. Natl. Acad. Sci. USA 88:10711-10715 (1991).
RN [2]; RE0015346.
RX PUBMED: 9417909.
RA Chapman G., Remiszewski J. L., Webb G. C., Schulz T. C., Bottema C. D., Rathjen P. D.
RT The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo
RL Genomics 46:223-233 (1997).
RN [3]; RE0015359.
RA Frohman M. A., Dickinson M. E., Hogan B. L. M., Martin G. R.
RT Mapping of Gbx-1 to mouse chromosome 5 and Gbx-2 to mouse chromosome 1
RL Mouse Genome 91:323-325 (1993).
RN [4]; RE0035288.
RX PUBMED: 15829521.
RA Lin Z., Cantos R., Patente M., Wu D. K.
RT Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling.
RL Development 132:2309-2318 (2005).
RN [5]; RE0054218.
RX PUBMED: 17060451.
RA Heimbucher T., Murko C., Bajoghli B., Aghaallaei N., Huber A., Stebegg R., Eberhard D., Fink M., Simeone A., Czerny T.
RT Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors.
RL Mol. Cell. Biol. 27:340-351 (2007).
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